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(Q21124897)
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NADPH oxidase 5
mammalian protein found in Homo sapiens
NADPH oxidase, EF-hand calcium binding domain 5
NOX5
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q96PH1
part of
transmembrane 1-electron transfer carrier
1 reference
Transporter Classification Database ID
5.B.1.1.5
retrieved
2 October 2019
based on heuristic
hierarchical database ID heuristic
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q96PH1
encoded by
NOX5
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q96PH1
molecular function
metal ion binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q96PH1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PH1
determination method
IEA
proton channel activity
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
A Ca(2+)-activated NADPH oxidase in testis, spleen, and lymph nodes
GOA
curator
UniProt
UniProt protein ID
Q96PH1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PH1
determination method
IDA
calcium ion binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PH1
determination method
IEA
heme binding
determination method
NAS
1 reference
retrieved
8 April 2019
stated in
A Ca(2+)-activated NADPH oxidase in testis, spleen, and lymph nodes
GOA
curator
UniProt
UniProt protein ID
Q96PH1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PH1
determination method
NAS
oxidoreductase activity
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q96PH1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PH1
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PH1
determination method
IEA
flavin adenine dinucleotide binding
determination method
NAS
1 reference
retrieved
8 April 2019
stated in
A Ca(2+)-activated NADPH oxidase in testis, spleen, and lymph nodes
GOA
curator
UniProt
UniProt protein ID
Q96PH1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PH1
determination method
NAS
NADP binding
determination method
NAS
1 reference
retrieved
8 April 2019
stated in
A Ca(2+)-activated NADPH oxidase in testis, spleen, and lymph nodes
GOA
curator
UniProt
UniProt protein ID
Q96PH1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PH1
determination method
NAS
protein binding
determination method
IPI
1 reference
retrieved
31 January 2018
stated in
NADPH oxidase 5 (NOX5) interacts with and is regulated by calmodulin
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96PH1&geneProductId=UniProtKB:Q96PH1
determination method
IPI
superoxide-generating NAD(P)H oxidase activity
determination method
IEA
IDA
TAS
3 references
retrieved
1 January 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96PH1&geneProductId=UniProtKB:Q96PH1
determination method
TAS
retrieved
1 January 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96PH1&geneProductId=UniProtKB:Q96PH1
determination method
IEA
retrieved
1 January 2018
stated in
A Ca(2+)-activated NADPH oxidase in testis, spleen, and lymph nodes
GOA
curator
UniProt
UniProt protein ID
Q96PH1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96PH1&geneProductId=UniProtKB:Q96PH1
determination method
IDA
superoxide-generating NAD(P)H oxidase activity
determination method
IBA
IDA
IEA
3 references
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PH1
determination method
IEA
retrieved
8 April 2019
stated in
A Ca(2+)-activated NADPH oxidase in testis, spleen, and lymph nodes
GOA
curator
UniProt
UniProt protein ID
Q96PH1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PH1
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PH1
determination method
IBA
cell component
integral component of membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q96PH1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PH1
determination method
IEA
membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q96PH1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PH1
determination method
IEA
endoplasmic reticulum
determination method
IDA
IEA
2 references
retrieved
31 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q96PH1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96PH1&geneProductId=UniProtKB:Q96PH1
determination method
IEA
retrieved
31 January 2018
stated in
NOX5 variants are functionally active in endothelial cells
GOA
curator
UniProt
UniProt protein ID
Q96PH1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96PH1&geneProductId=UniProtKB:Q96PH1
determination method
IDA
endoplasmic reticulum membrane
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PH1
determination method
TAS
endoplasmic reticulum
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q96PH1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PH1
determination method
IEA
plasma membrane
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PH1
determination method
IBA
NADPH oxidase complex
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PH1
determination method
IBA
biological process
angiogenesis
determination method
IDA
IEA
2 references
retrieved
31 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q96PH1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96PH1&geneProductId=UniProtKB:Q96PH1
determination method
IEA
retrieved
31 January 2018
stated in
NOX5 variants are functionally active in endothelial cells
GOA
curator
UniProt
UniProt protein ID
Q96PH1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96PH1&geneProductId=UniProtKB:Q96PH1
determination method
IDA
superoxide anion generation
determination method
IDA
IEA
2 references
retrieved
1 January 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96PH1&geneProductId=UniProtKB:Q96PH1
determination method
IEA
retrieved
1 January 2018
stated in
A Ca(2+)-activated NADPH oxidase in testis, spleen, and lymph nodes
GOA
curator
UniProt
UniProt protein ID
Q96PH1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96PH1&geneProductId=UniProtKB:Q96PH1
determination method
IDA
positive regulation of reactive oxygen species metabolic process
determination method
IDA
1 reference
retrieved
31 January 2018
stated in
NOX5 variants are functionally active in endothelial cells
GOA
curator
UniProt
UniProt protein ID
Q96PH1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96PH1&geneProductId=UniProtKB:Q96PH1
determination method
IDA
regulation of fusion of sperm to egg plasma membrane
determination method
NAS
1 reference
retrieved
8 April 2019
stated in
A Ca(2+)-activated NADPH oxidase in testis, spleen, and lymph nodes
GOA
curator
UniProt
UniProt protein ID
Q96PH1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PH1
determination method
NAS
apoptotic process
determination method
NAS
1 reference
retrieved
8 April 2019
stated in
A Ca(2+)-activated NADPH oxidase in testis, spleen, and lymph nodes
GOA
curator
UniProt
UniProt protein ID
Q96PH1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PH1
determination method
NAS
ion transport
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q96PH1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PH1
determination method
IEA
regulation of proton transport
determination method
NAS
1 reference
retrieved
8 April 2019
stated in
A Ca(2+)-activated NADPH oxidase in testis, spleen, and lymph nodes
GOA
curator
UniProt
UniProt protein ID
Q96PH1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PH1
determination method
NAS
cell population proliferation
determination method
NAS
1 reference
retrieved
8 April 2019
stated in
A Ca(2+)-activated NADPH oxidase in testis, spleen, and lymph nodes
GOA
curator
UniProt
UniProt protein ID
Q96PH1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PH1
determination method
NAS
endothelial cell proliferation
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
NOX5 variants are functionally active in endothelial cells
GOA
curator
UniProt
UniProt protein ID
Q96PH1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PH1
determination method
IDA
cellular response to oxidative stress
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PH1
determination method
TAS
proton transmembrane transport
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PH1
determination method
IEA
cytoskeleton-dependent cytokinesis
determination method
NAS
1 reference
retrieved
8 April 2019
stated in
A Ca(2+)-activated NADPH oxidase in testis, spleen, and lymph nodes
GOA
curator
UniProt
UniProt protein ID
Q96PH1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PH1
determination method
NAS
angiogenesis
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q96PH1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PH1
determination method
IEA
defense response
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PH1
determination method
IBA
superoxide anion generation
determination method
IBA
IDA
IEA
3 references
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PH1
determination method
IEA
retrieved
8 April 2019
stated in
A Ca(2+)-activated NADPH oxidase in testis, spleen, and lymph nodes
GOA
curator
UniProt
UniProt protein ID
Q96PH1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PH1
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96PH1
determination method
IBA
Identifiers
MeSH descriptor ID
C431571
subject named as
NOX5 protein, human
0 references
RefSeq protein ID
NP_001171708
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
79400
NP_001171709
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
79400
NP_078781
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
79400
UniProt protein ID
Q96PH1
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q96PH1
Ensembl protein ID
ENSP00000373518
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000373518
ENSP00000410887
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000410887
ENSP00000416828
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000416828
ENSP00000432440
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000432440
ENSP00000454143
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000454143
ENSP00000455703
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000455703
Transporter Classification Database ID
5.B.1.1.5
2 references
stated in
Transporter Classification database
retrieved
13 March 2020
stated in
Transporter Classification database
retrieved
29 April 2020
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