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Telomerase associated protein 1
mammalian protein found in Homo sapiens
Telomerase-associated protein 1
TEP1
telomerase protein component 1
p240
telomerase protein 1
TROVE domain family, member 1
p80 telomerase homolog
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q99973
part of
WD40/YVTN repeat-like-containing domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q99973
WD40-repeat-containing domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q99973
TROVE domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q99973
P-loop containing nucleoside triphosphate hydrolase
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q99973
TROVE domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
NACHT nucleoside triphosphatase family
1 reference
based on heuristic
inferred from protein domain or family
Domain of unknown function DUF4062, protein family
1 reference
based on heuristic
inferred from protein domain or family
WD40 repeat, protein family
1 reference
based on heuristic
inferred from protein domain or family
WD40 repeat, conserved site, protein family
1 reference
based on heuristic
inferred from protein domain or family
TEP1, N-terminal domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q99973
encoded by
TEP1
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q99973
molecular function
ATP binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q99973
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99973
determination method
IEA
p53 binding
determination method
IPI
1 reference
retrieved
8 April 2019
stated in
Molecular interactions between telomerase and the tumor suppressor protein p53 in vitro
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99973
determination method
IPI
nucleotide binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q99973
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99973
determination method
IEA
enzyme binding
determination method
IPI
1 reference
retrieved
8 April 2019
stated in
Vault poly(ADP-ribose) polymerase is associated with mammalian telomerase and is dispensable for telomerase function and vault structure in vivo
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99973
determination method
IPI
telomerase RNA binding
determination method
ISS
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99973
determination method
ISS
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99973
determination method
IEA
telomerase activity
determination method
IDA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99973
determination method
IEA
retrieved
8 April 2019
stated in
Differential regulation of telomerase activity by six telomerase subunits
GOA
curator
UniProt
UniProt protein ID
Q99973
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99973
determination method
IDA
RNA binding
determination method
IBA
IEA
ISS
5 references
retrieved
27 March 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q99973
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99973&geneProductId=UniProtKB:Q99973
determination method
ISS
retrieved
27 March 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q99973
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99973&geneProductId=UniProtKB:Q99973
determination method
IEA
retrieved
27 March 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99973&geneProductId=UniProtKB:Q99973
determination method
IEA
retrieved
27 March 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99973&geneProductId=UniProtKB:Q99973
determination method
IEA
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99973&geneProductId=UniProtKB:Q99973
determination method
IBA
RNA binding
determination method
IEA
ISS
4 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q99973
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99973
determination method
ISS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q99973
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99973
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99973
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99973
determination method
IEA
cell component
telomere
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q99973
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99973
determination method
IEA
telomerase holoenzyme complex
determination method
IDA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99973
determination method
IEA
retrieved
8 April 2019
stated in
Differential regulation of telomerase activity by six telomerase subunits
GOA
curator
UniProt
UniProt protein ID
Q99973
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99973
determination method
IDA
nucleus
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q99973
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99973
determination method
IEA
cytoplasm
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
TRiC-P5, a novel TCP1-related protein, is localized in the cytoplasm and in the nuclear matrix
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99973
determination method
IDA
nuclear matrix
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
TRiC-P5, a novel TCP1-related protein, is localized in the cytoplasm and in the nuclear matrix
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99973
determination method
IDA
chromosome
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q99973
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99973
determination method
IEA
U5 snRNP
determination method
IBA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99973&geneProductId=UniProtKB:Q99973
determination method
IBA
precatalytic spliceosome
determination method
IBA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99973&geneProductId=UniProtKB:Q99973
determination method
IBA
catalytic step 2 spliceosome
determination method
IBA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99973&geneProductId=UniProtKB:Q99973
determination method
IBA
ribonucleoprotein complex
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
The p80 homology region of TEP1 is sufficient for its association with the telomerase and vault RNAs, and the vault particle
GOA
curator
UniProt
UniProt protein ID
Q99973
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99973
determination method
TAS
biological process
telomere maintenance via recombination
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Telomerase activity is down regulated via decreases in hTERT mRNA but not TEP1 mRNA or hTERC during the differentiation of leukemic cells
GOA
curator
UniProt
UniProt protein ID
Q99973
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99973
determination method
IDA
RNA-dependent DNA biosynthetic process
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99973
determination method
IEA
RNA splicing
determination method
IBA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99973&geneProductId=UniProtKB:Q99973
determination method
IBA
has part(s)
WD40 repeat
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q99973
Domain of unknown function DUF4062
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q99973
WD40 repeat, conserved site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q99973
TROVE domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q99973
TEP1, N-terminal
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q99973
NACHT nucleoside triphosphatase domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q99973
Identifiers
RefSeq protein ID
NP_001305964
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
7011
NP_009041
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
7011
XP_005268084
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
7011
XP_011535412
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
7011
UniProt protein ID
Q99973
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q99973
Ensembl protein ID
ENSP00000262715
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000262715
ENSP00000450475
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000450475
ENSP00000450508
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000450508
ENSP00000450541
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000450541
ENSP00000450830
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000450830
ENSP00000451409
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000451409
ENSP00000451634
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000451634
ENSP00000451919
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000451919
ENSP00000452240
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000452240
ENSP00000452574
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000452574
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