(Q21130783)

http://www.ebi.ac.uk/interpro/protein/Q9NZ42

1 reference

13 November 2019

1 reference

13 November 2019

3 references

8 April 2019

TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ42

8 April 2019

Ferritin light chain interacts with PEN-2 and affects γ-secretase activity

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ42

8 April 2019

Cellular localization of Nicastrin affects amyloid beta species production

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ42

endoplasmic reticulum membrane

IPI

cell component

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ42

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ42

integral component of plasma membrane

1 reference

8 April 2019

Purification and characterization of the human gamma-secretase complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ42

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ42

Golgi cisterna membrane

1 reference

8 April 2019

integral component of membrane

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ42

8 April 2019

Three-dimensional structure of human γ-secretase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ42

8 April 2019

An atomic structure of human γ-secretase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ42

2 references

gamma-secretase complex

3 references

8 April 2019

Three-dimensional structure of human γ-secretase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ42

8 April 2019

An atomic structure of human γ-secretase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ42

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ42

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ42

1 reference

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ42

integral component of presynaptic membrane

1 reference

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ42

1 reference

8 April 2019

Purification and characterization of the human gamma-secretase complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ42

positive regulation of catalytic activity

1 reference

8 April 2019

Purification and characterization of the human gamma-secretase complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ42

membrane protein ectodomain proteolysis

1 reference

8 April 2019

Purification and characterization of the human gamma-secretase complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ42

amyloid precursor protein catabolic process

1 reference

8 April 2019

Purification and characterization of the human gamma-secretase complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ42

Notch receptor processing, ligand-dependent

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ42

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ42

Notch signaling pathway

1 reference

8 April 2019

Notch receptor processing

3 references

1 January 2018

Purification and characterization of the human gamma-secretase complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ42

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ42

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ42

membrane protein intracellular domain proteolysis

IBA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ42

positive regulation of apoptotic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ42

ephrin receptor signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZ42

physically interacts with

1 reference

Open Targets Platform

retrieved

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1090771

1 reference

Open Targets Platform

retrieved

14 August 2023

https://platform.opentargets.org/drug/CHEMBL463981

1 reference

Open Targets Platform

retrieved

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1770916

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016