(Q21131645)

English

ER lipid raft associated 1

mammalian protein found in Homo sapiens

stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1
SPFH domain-containing protein 1
Band_7 23-211 Keo4 (Interim) similar to C.elegans protein C42C1.9
ERLIN1
Protein KE04
endoplasmic reticulum lipid raft-associated protein 1
SPFH domain family, member 1
erlin-1

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Statements

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

27 March 2018

Erlins restrict SREBP activation in the ER and regulate cellular cholesterol homeostasis

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75477&geneProductId=UniProtKB:O75477

4 references

8 April 2019

An endoplasmic reticulum (ER) membrane complex composed of SPFH1 and SPFH2 mediates the ER-associated degradation of inositol 1,4,5-trisphosphate receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75477

8 April 2019

Membrane-associated ubiquitin ligase complex containing gp78 mediates sterol-accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75477

8 April 2019

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75477

8 April 2019

A proteome-scale map of the human interactome network

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75477

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75477

determination method

IEA

ubiquitin protein ligase binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75477

determination method

IEA

cell component

integral component of membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75477

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75477

determination method

IEA

endoplasmic reticulum membrane

4 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75477&geneProductId=UniProtKB:O75477

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75477&geneProductId=UniProtKB:O75477

27 March 2018

Erlin-1 and erlin-2 are novel members of the prohibitin family of proteins that define lipid-raft-like domains of the ER

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75477&geneProductId=UniProtKB:O75477

27 March 2018

An endoplasmic reticulum (ER) membrane complex composed of SPFH1 and SPFH2 mediates the ER-associated degradation of inositol 1,4,5-trisphosphate receptors

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75477&geneProductId=UniProtKB:O75477

determination method

IDA

protein-containing complex

1 reference

8 April 2019

Blood pressure is regulated by an alpha1D-adrenergic receptor/dystrophin signalosome

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75477

determination method

IDA

endoplasmic reticulum membrane

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75477

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75477

8 April 2019

Erlin-1 and erlin-2 are novel members of the prohibitin family of proteins that define lipid-raft-like domains of the ER

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75477

8 April 2019

An endoplasmic reticulum (ER) membrane complex composed of SPFH1 and SPFH2 mediates the ER-associated degradation of inositol 1,4,5-trisphosphate receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75477

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75477

determination method

IBA

biological process

SREBP signaling pathway

1 reference

27 March 2018

Erlins restrict SREBP activation in the ER and regulate cellular cholesterol homeostasis

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75477&geneProductId=UniProtKB:O75477

determination method

IMP

steroid metabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75477

determination method

IEA

cholesterol metabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75477

determination method

IEA

negative regulation of cholesterol biosynthetic process

1 reference

8 April 2019

Erlins restrict SREBP activation in the ER and regulate cellular cholesterol homeostasis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75477

determination method

IMP

negative regulation of fatty acid biosynthetic process

1 reference

8 April 2019

Erlins restrict SREBP activation in the ER and regulate cellular cholesterol homeostasis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75477

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75477

determination method

IEA

transmembrane transport

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75477

1 reference

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O75477

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

Transporter Classification Database ID

1.P.1.1.1

2 references

stated in

Transporter Classification database

retrieved

13 March 2020

stated in

Transporter Classification database

retrieved

29 April 2020

(Q21131645)

ER lipid raft associated 1

Statements

Identifiers

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