(Q21131683)

http://www.ebi.ac.uk/interpro/protein/Q96RU7

Protein kinase-like domain superfamily

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q96RU7

Protein kinase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

ubiquitin-protein transferase regulator activity

1 reference

8 April 2019

Differential ability of Tribbles family members to promote degradation of C/EBPalpha and induce acute myelogenous leukemia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RU7

protein kinase inhibitor activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RU7

1 reference

8 April 2019

SKIP3, a novel Drosophila tribbles ortholog, is overexpressed in human tumors and is regulated by hypoxia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RU7

8 references

8 April 2019

Critical and functional regulation of CHOP (C/EBP homologous protein) through the N-terminal portion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RU7

8 April 2019

SKIP3, a novel Drosophila tribbles ortholog, is overexpressed in human tumors and is regulated by hypoxia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RU7

8 April 2019

TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RU7

8 April 2019

A proteome-scale map of the human interactome network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RU7

8 April 2019

Analysis of BCL6-interacting proteins by tandem mass spectrometry

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RU7

8 April 2019

Widespread macromolecular interaction perturbations in human genetic disorders

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RU7

8 April 2019

A Y2H-seq approach defines the human protein methyltransferase interactome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RU7

8 April 2019

SKIP3, a novel Drosophila tribbles ortholog, is overexpressed in human tumors and is regulated by hypoxia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RU7

mitogen-activated protein kinase kinase binding

IPI

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RU7

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RU7

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RU7

protein kinase binding

3 references

8 April 2019

8 April 2019

Human tribbles, a protein family controlling mitogen-activated protein kinase cascades

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RU7

8 April 2019

TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RU7

ubiquitin protein ligase binding

IPI

1 reference

8 April 2019

TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RU7

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RU7

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RU7

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RU7

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RU7

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RU7

negative regulation of fat cell differentiation

IBA

biological process

1 reference

8 April 2019

TRB2, a mouse Tribbles ortholog, suppresses adipocyte differentiation by inhibiting AKT and C/EBPbeta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RU7

regulation of transcription, DNA-templated

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96RU7&geneProductId=UniProtKB:Q96RU7

negative regulation of fatty acid biosynthetic process

1 reference

8 April 2019

TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RU7

negative regulation of protein kinase activity

1 reference

8 April 2019

TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RU7

negative regulation of transcription by RNA polymerase II

1 reference

8 April 2019

TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RU7

transcription, DNA-templated

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96RU7&geneProductId=UniProtKB:Q96RU7

response to endoplasmic reticulum stress

1 reference

8 April 2019

TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RU7

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RU7

protein phosphorylation

1 reference

8 April 2019

intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

positive regulation of ubiquitin-protein transferase activity

TAS

1 reference

8 April 2019

TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RU7

cellular response to insulin stimulus

1 reference

8 April 2019

TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RU7

regulation of MAP kinase activity

1 reference

5 June 2018

Human tribbles, a protein family controlling mitogen-activated protein kinase cascades

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96RU7&geneProductId=UniProtKB:Q96RU7

positive regulation of protein binding

1 reference

8 April 2019

TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RU7

negative regulation of transcription, DNA-templated

1 reference

8 April 2019

TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RU7

regulation of glucose transmembrane transport

IMP

1 reference

8 April 2019

TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RU7

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RU7

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RU7

regulation of lipid metabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RU7

negative regulation of protein kinase B signaling

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RU7

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96RU7

TAS

regulation of autophagy

1 reference

8 April 2019

has part(s)

protein kinase domain

1 reference

stated in

InterPro Release 71.0