(Q21132016)

Short-chain dehydrogenase/reductase SDR

1 reference

WW domain superfamily

1 reference

WW domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

transcription coactivator activity

4 references

27 February 2018

Transforming growth factor beta1 signaling via interaction with cell surface Hyal-2 and recruitment of WWOX/WOX1

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NZC7&geneProductId=UniProtKB:Q9NZC7

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NZC7&geneProductId=UniProtKB:Q9NZC7

8 April 2019

Transforming growth factor beta1 signaling via interaction with cell surface Hyal-2 and recruitment of WWOX/WOX1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZC7

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZC7

protein dimerization activity

1 reference

8 April 2019

WWOX, a novel WW domain-containing protein mapping to human chromosome 16q23.3-24.1, a region frequently affected in breast cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZC7

7 references

8 April 2019

WWOX binds the specific proline-rich ligand PPXY: identification of candidate interacting proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZC7

8 April 2019

Inhibition of the Wnt/beta-catenin pathway by the WWOX tumor suppressor protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZC7

8 April 2019

A WWOX-binding molecule, transmembrane protein 207, is related to the invasiveness of gastric signet-ring cell carcinoma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZC7

8 April 2019

The Tumor-Suppressor WWOX and HDAC3 Inhibit the Transcriptional Activity of the β-Catenin Coactivator BCL9-2 in Breast Cancer Cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZC7

8 April 2019

17beta-Estradiol upregulates and activates WOX1/WWOXv1 and WOX2/WWOXv2 in vitro: potential role in cancerous progression of breast and prostate to a premetastatic state in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZC7

8 April 2019

WWOX binds the specific proline-rich ligand PPXY: identification of candidate interacting proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZC7

8 April 2019

WW domain-containing proteins, WWOX and YAP, compete for interaction with ErbB-4 and modulate its transcriptional function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZC7

WWOX, a novel WW domain-containing protein mapping to human chromosome 16q23.3-24.1, a region frequently affected in breast cancer

IPI

oxidoreductase activity

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZC7

8 April 2019

Common chromosomal fragile site FRA16D sequence: identification of the FOR gene spanning FRA16D and homozygous deletions and translocation breakpoints in cancer cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZC7

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZC7

3 references

8 April 2019

WWOX, a novel WW domain-containing protein mapping to human chromosome 16q23.3-24.1, a region frequently affected in breast cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZC7

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZC7

8 April 2019

Inhibition of the Wnt/beta-catenin pathway by the WWOX tumor suppressor protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZC7

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZC7

8 April 2019

WWOX binds the specific proline-rich ligand PPXY: identification of candidate interacting proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZC7

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZC7

1 reference

8 April 2019

Transforming growth factor beta1 signaling via interaction with cell surface Hyal-2 and recruitment of WWOX/WOX1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZC7

1 reference

8 April 2019

Transforming growth factor beta1 signaling via interaction with cell surface Hyal-2 and recruitment of WWOX/WOX1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZC7

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZC7

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZC7

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZC7

8 April 2019

Transforming growth factor beta1 signaling via interaction with cell surface Hyal-2 and recruitment of WWOX/WOX1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZC7

steroid metabolic process

IDA

biological process

1 reference

8 April 2019

WWOX, a novel WW domain-containing protein mapping to human chromosome 16q23.3-24.1, a region frequently affected in breast cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZC7

extrinsic apoptotic signaling pathway

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZC7

negative regulation of Wnt signaling pathway

1 reference

8 April 2019

Inhibition of the Wnt/beta-catenin pathway by the WWOX tumor suppressor protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZC7

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZC7

IDA

Wnt signaling pathway

1 reference

8 April 2019

positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZC7

osteoblast differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZC7

intrinsic apoptotic signaling pathway by p53 class mediator

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZC7

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZC7

negative regulation of transcription by RNA polymerase II

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NZC7

transcription by RNA polymerase II

TAS

1 reference

27 February 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NZC7&geneProductId=UniProtKB:Q9NZC7

1 reference

D08.811.682.047.820.900.500

Identifiers

MeSH descriptor ID

D000074584

subject named as

WW Domain-Containing Oxidoreductase

0 references

MeSH tree code

0 references

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

language of work or name

1 reference

inferred by common MeSH mappings on source and on Wikidata