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G protein-coupled receptor kinase 4
mammalian protein found in Homo sapiens
GRK4
G protein-coupled receptor kinase 2-like
ITI1
G protein-coupled receptor kinase GRK4
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P32298
part of
GPCR kinase
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P32298
Protein kinase-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P32298
RGS domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P32298
Regulator of G protein signalling
1 reference
based on heuristic
inferred from protein domain or family
AGC-kinase, C-terminal domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Protein kinase domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Protein kinase, ATP binding site, protein family
1 reference
based on heuristic
inferred from protein domain or family
Serine/threonine-protein kinase, active site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P32298
encoded by
GRK4
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P32298
molecular function
transferase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P32298
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32298
determination method
IEA
nucleotide binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P32298
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32298
determination method
IEA
protein kinase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32298
determination method
IEA
G protein-coupled receptor kinase activity
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P32298
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32298
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32298
determination method
IEA
kinase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P32298
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32298
determination method
IEA
protein serine/threonine kinase activity
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P32298
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32298
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32298
determination method
IEA
ATP binding
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P32298
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32298
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32298
determination method
IEA
rhodopsin kinase activity
determination method
IEA
TAS
2 references
retrieved
7 November 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P32298&geneProductId=UniProtKB:P32298
determination method
TAS
retrieved
7 November 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P32298&geneProductId=UniProtKB:P32298
determination method
IEA
rhodopsin kinase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32298
determination method
IEA
cell component
cytoplasm
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P32298
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32298
determination method
IEA
cytosol
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32298
determination method
IEA
neuronal cell body
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32298
determination method
IEA
dendrite
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32298
determination method
IEA
cell cortex
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P32298
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32298
determination method
IEA
photoreceptor disc membrane
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32298
determination method
TAS
biological process
G protein-coupled receptor internalization
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32298
determination method
IEA
regulation of G protein-coupled receptor signaling pathway
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
A novel G protein-coupled receptor kinase gene cloned from 4p16.3
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32298
determination method
TAS
phosphorylation
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P32298
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32298
determination method
IEA
regulation of rhodopsin mediated signaling pathway
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32298
determination method
TAS
receptor internalization
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Function of the cytoplasmic tail of human calcitonin receptor-like receptor in complex with receptor activity-modifying protein 2
GOA
curator
UniProt
UniProt protein ID
P32298
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32298
determination method
IDA
protein phosphorylation
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32298
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32298
determination method
IEA
desensitization of G protein-coupled receptor signaling pathway
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32298
determination method
IEA
signal transduction
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32298
determination method
IEA
physically interacts with
balanol
has use
enzyme inhibitor
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
8142
language of work or name
English
retrieved
17 August 2016
has part(s)
RGS domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P32298
AGC-kinase, C-terminal
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P32298
protein kinase, ATP binding site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P32298
protein kinase domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P32298
serine/threonine-protein kinase, active site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P32298
Identifiers
MeSH descriptor ID
D054771
subject named as
G-Protein-Coupled Receptor Kinase 4
0 references
MeSH tree code
D08.811.913.696.620.682.700.364.550
0 references
D12.776.476.563.364.550
0 references
RefSeq protein ID
NP_001004056
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2868
NP_001004057
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2868
NP_005298
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2868
NP_892027
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2868
XP_005248019
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2868
XP_006713943
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2868
XP_011511749
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2868
XP_011511750
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2868
XP_011511751
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2868
XP_011511752
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2868
XP_011511753
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2868
XP_011511754
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2868
XP_011511755
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2868
XP_011511756
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2868
XP_011511757
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2868
XP_011511758
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2868
XP_011511759
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2868
XP_016863541
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2868
XP_016863542
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2868
XP_016863543
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2868
XP_016863544
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2868
XP_016863545
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2868
XP_016863546
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2868
XP_016863547
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2868
XP_016863548
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2868
XP_016863551
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2868
XP_016863552
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2868
XP_016863553
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2868
XP_016863554
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2868
XP_016863555
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2868
NP_001337102
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2868
XP_024309783
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2868
UniProt protein ID
P32298
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P32298
Ensembl protein ID
ENSP00000264764
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000264764
ENSP00000381128
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000381128
ENSP00000381129
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000381129
ENSP00000427445
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000427445
ENSP00000421650
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000421650
PDB structure ID
4YHJ
1 reference
stated in
UniProt
UniProt protein ID
P32298
retrieved
9 August 2016
language of work or name
English
UMLS CUI
C0252901
1 reference
based on heuristic
inferred by common MeSH mappings on source and on Wikidata
stated in
UMLS 2023
retrieved
25 May 2023
Sitelinks
Wikipedia
(0 entries)
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Wikibooks
(0 entries)
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Wikinews
(0 entries)
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Wikiquote
(0 entries)
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Wikisource
(0 entries)
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Wikiversity
(0 entries)
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Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
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Multilingual sites
(0 entries)
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