(Q21133134)

http://www.ebi.ac.uk/interpro/protein/P26583

High mobility group box domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

HMG box A DNA-binding domain, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

3 references

8 April 2019

HMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

protein domain specific binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

DNA-binding transcription factor activity

1 reference

26 September 2017

HMGB1 and HMGB2 proteins up-regulate cellular expression of human topoisomerase IIalpha

http://www.ebi.ac.uk/QuickGO/annotations?protein=P26583&geneProductId=UniProtKB:P26583

non-sequence-specific DNA binding, bending

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

1 reference

8 April 2019

Localization of the binding region of high mobility group protein 2 to cisplatin-damaged DNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

3 references

8 April 2019

HMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

8 April 2019

A proteome-scale map of the human interactome network

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

8 April 2019

Chromatin components as part of a putative transcriptional repressing complex

GOA

curator

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

four-way junction DNA binding

IPI

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

High mobility group B2 is secreted by myeloid cells and has mitogenic and chemoattractant activities similar to high mobility group B1

RAGE receptor binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

High mobility group B2 is secreted by myeloid cells and has mitogenic and chemoattractant activities similar to high mobility group B1

IGI

chemoattractant activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

supercoiled DNA binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

transcription coactivator activity

1 reference

8 April 2019

HMGB1 and HMGB2 proteins up-regulate cellular expression of human topoisomerase IIalpha

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

transcription factor binding

3 references

8 April 2019

The nonspecific DNA-binding and -bending proteins HMG1 and HMG2 promote the assembly of complex nucleoprotein structures

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

8 April 2019

HMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

3 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P26583&geneProductId=UniProtKB:P26583

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P26583&geneProductId=UniProtKB:P26583

26 September 2017

HMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A

http://www.ebi.ac.uk/QuickGO/annotations?protein=P26583&geneProductId=UniProtKB:P26583

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

perinuclear region of cytoplasm

1 reference

8 April 2019

Association of chromatin proteins high mobility group box (HMGB) 1 and HMGB2 with mitotic chromosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

6 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

8 April 2019

The nonspecific DNA-binding and -bending proteins HMG1 and HMG2 promote the assembly of complex nucleoprotein structures

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

8 April 2019

HMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

8 April 2019

HMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

protein-containing complex

1 reference

8 April 2019

HMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

positive regulation of interferon-beta production

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

1 reference

8 April 2019

HMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P26583&geneProductId=UniProtKB:P26583

apoptotic DNA fragmentation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

TAS

male gonad development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

regulation of transcription, DNA-templated

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P26583&geneProductId=UniProtKB:P26583

positive regulation of endothelial cell proliferation

1 reference

8 April 2019

High mobility group B2 is secreted by myeloid cells and has mitogenic and chemoattractant activities similar to high mobility group B1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

positive regulation of erythrocyte differentiation

1 reference

8 April 2019

High-mobility group protein HMGB2 regulates human erythroid differentiation through trans-activation of GFI1B transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

IMP

immune system process

1 reference

8 April 2019

response to steroid hormone

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

HMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A

chromatin organization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

negative regulation of gene expression

NAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

transcription, DNA-templated

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P26583&geneProductId=UniProtKB:P26583

positive regulation of transcription, DNA-templated

1 reference

8 April 2019

High-mobility group protein HMGB2 regulates human erythroid differentiation through trans-activation of GFI1B transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

positive regulation of gene expression

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

positive regulation of nuclease activity

1 reference

8 April 2019

Pharmaceutical applications of solid dispersion systems: dissolution of griseofulvin-succinic acid eutectic mixture

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

defense response to Gram-negative bacterium

1 reference

8 April 2019

Antimicrobial activity of high-mobility-group box 2: a new function to a well-known protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

positive regulation of innate immune response

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P26583&geneProductId=UniProtKB:P26583

1 reference

8 April 2019

High mobility group B2 is secreted by myeloid cells and has mitogenic and chemoattractant activities similar to high mobility group B1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

DNA ligation involved in DNA repair

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

spermatid nucleus differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

innate immune response

1 reference

8 April 2019

negative regulation of transcription, DNA-templated

1 reference

8 April 2019

Chromatin components as part of a putative transcriptional repressing complex

GOA

curator

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

cellular response to lipopolysaccharide

1 reference

8 April 2019

High mobility group B2 is secreted by myeloid cells and has mitogenic and chemoattractant activities similar to high mobility group B1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

IEP

inflammatory response

1 reference

8 April 2019

positive regulation of megakaryocyte differentiation

1 reference

8 April 2019

High-mobility group protein HMGB2 regulates human erythroid differentiation through trans-activation of GFI1B transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

positive regulation of transcription by RNA polymerase II

IMP

3 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P26583&geneProductId=UniProtKB:P26583

26 September 2017

High-mobility group protein HMGB2 regulates human erythroid differentiation through trans-activation of GFI1B transcription

http://www.ebi.ac.uk/QuickGO/annotations?protein=P26583&geneProductId=UniProtKB:P26583

26 September 2017

HMGB1 and HMGB2 proteins up-regulate cellular expression of human topoisomerase IIalpha

http://www.ebi.ac.uk/QuickGO/annotations?protein=P26583&geneProductId=UniProtKB:P26583

defense response to Gram-positive bacterium

1 reference

8 April 2019

Antimicrobial activity of high-mobility-group box 2: a new function to a well-known protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

regulation of transcription by RNA polymerase II

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

8 April 2019

Activation of the TFIID-TFIIA complex with HMG-2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

positive regulation of transcription by RNA polymerase II

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

8 April 2019

HMGB1 and HMGB2 proteins up-regulate cellular expression of human topoisomerase IIalpha

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

8 April 2019

High-mobility group protein HMGB2 regulates human erythroid differentiation through trans-activation of GFI1B transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P26583

High mobility group box domain

has part(s)

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P26583

HMG box A DNA-binding domain, conserved site

1 reference

stated in

InterPro Release 71.0