(Q21133932)

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Slow receptor dissociation kinetics differentiate macitentan from other endothelin receptor antagonists in pulmonary arterial smooth muscle cells

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scholarly article

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Slow receptor dissociation kinetics differentiate macitentan from other endothelin receptor antagonists in pulmonary arterial smooth muscle cells (English)

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1 reference

ChEBI release 2020-05-28

author name string

John Gatfield

1

author given names

John

author last names

Gatfield

1 reference

PubMed publication ID

17 August 2022

Celia Mueller Grandjean

2

author given names

Celia

author last names

Mueller Grandjean

1 reference

PubMed publication ID

17 August 2022

Thomas Sasse

3

author given names

Thomas

author last names

Sasse

1 reference

PubMed publication ID

17 August 2022

Martine Clozel

4

author given names

Martine

author last names

Clozel

1 reference

PubMed publication ID

17 August 2022

Oliver Nayler

5

author given names

Oliver

author last names

Nayler

1 reference

PubMed publication ID

17 August 2022

language of work or name

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publication date

2012

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7

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10

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e47662

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copyright license

Creative Commons Attribution 4.0 International

15 October 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Long-lasting target binding and rebinding as mechanisms to prolong in vivo drug action

1 reference

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19 March 2017

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

1 reference

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19 March 2017

P2Y12, a new platelet ADP receptor, target of clopidogrel

1 reference

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19 March 2017

Inositol trisphosphate and calcium signalling

1 reference

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19 March 2017

Cloning and expression of human endothelin-1 receptor cDNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471877

19 March 2017

Molecular cloning of a non-isopeptide-selective human endothelin receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471877

19 March 2017

Smooth muscle cell hypertrophy, proliferation, migration and apoptosis in pulmonary hypertension

1 reference

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12 September 2017

New mechanisms of pulmonary arterial hypertension: role of Ca²⁺ signaling.

1 reference

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12 September 2017

The role of endothelin-1 in the pathogenesis of pulmonary arterial hypertension

1 reference

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12 September 2017

Functional and biochemical rationales for the 24-hour-long duration of action of olodaterol

1 reference

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12 September 2017

The role of endothelin-1 signaling in the fibrosis observed in systemic sclerosis

1 reference

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12 September 2017

Basic science of pulmonary arterial hypertension for clinicians: new concepts and experimental therapies

1 reference

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12 September 2017

Guidelines for the diagnosis and treatment of pulmonary hypertension: the Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the In

1 reference

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12 September 2017

Cellular and molecular basis of pulmonary arterial hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471877

12 September 2017

Endothelin receptor antagonists for pulmonary arterial hypertension: rationale and place in therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471877

12 September 2017

Mechanisms of ET-1-induced endothelial dysfunction

1 reference

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12 September 2017

Biochemical mechanisms of New Molecular Entities (NMEs) approved by United States FDA during 2001-2004: mechanisms leading to optimal efficacy and safety

1 reference

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12 September 2017

Biochemical characterization of desloratadine, a potent antagonist of the human histamine H(1) receptor

1 reference

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12 September 2017

AT(1)-receptor blockers: differences that matter

1 reference

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12 September 2017

The pathobiology of pulmonary hypertension. Endothelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471877

12 September 2017

Molecular regulation of the endothelin-1 gene by hypoxia. Contributions of hypoxia-inducible factor-1, activator protein-1, GATA-2, AND p300/CBP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471877

12 September 2017

Upregulated TRP and enhanced capacitative Ca(2+) entry in human pulmonary artery myocytes during proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471877

12 September 2017

Secretory pathways in endothelin synthesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471877

12 September 2017

Vascular biology of endothelin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471877

12 September 2017

Evidence using immunoelectron microscopy for regulated and constitutive pathways in the transport and release of endothelin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471877

12 September 2017

Distinct functions of nuclear and cytoplasmic calcium in the control of gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471877

12 September 2017

Regulation of endothelin 1 gene by fluid shear stress is transcriptionally mediated and independent of protein kinase C and cAMP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471877

12 September 2017

Rapid degradation of endothelin-1 by an enzyme released by the rat isolated perfused mesentery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471877

12 September 2017

ETA-receptor antagonists or allosteric modulators?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471877

27 September 2017

Pharmacology of macitentan, an orally active tissue-targeting dual endothelin receptor antagonist

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471877

27 September 2017

Determining the potency and molecular mechanism of action of insurmountable antagonists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471877

27 September 2017

Endothelin receptors and calcium signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471877

27 September 2017

Polar secretion of endothelin-1 by cultured endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471877

27 September 2017

Molecular characterisation of the interactions between olmesartan and telmisartan and the human angiotensin II AT1 receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471877

30 May 2018

Endothelin as a regulator of cardiovascular function in health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471877

30 May 2018

Vascular A10 cell membranes contain an endothelin metabolizing neutral endopeptidase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471877

30 May 2018

Survival in patients with idiopathic, familial, and anorexigen-associated pulmonary arterial hypertension in the modern management era.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471877

29 November 2018

ET(A) and ET(B) receptors modulate the proliferation of human pulmonary artery smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471877

29 November 2018

Endothelin-1 induces an angiogenic phenotype in cultured endothelial cells and stimulates neovascularization in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471877

29 November 2018

Sustained membrane depolarization and pulmonary artery smooth muscle cell proliferation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471877

29 November 2018

Expression of endothelin-1 in the lungs of patients with pulmonary hypertension.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471877

29 November 2018

Selective proteolitic activation and degradation of ETs and big ETs in parenchymal strips of the guinea-pig lung

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471877

29 November 2018

Endothelin-mediated calcium signaling in preglomerular smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23077657

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelin stimulates c-fos and c-myc expression and proliferation of vascular smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23077657

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucocorticoids induce endothelin release from vascular smooth muscle cells but not endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23077657

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelin-1 stimulates DNA synthesis and proliferation of pulmonary artery smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23077657

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and characterization of endothelin-1 degradation activity from porcine kidney

1 reference

https://pubmed.ncbi.nlm.nih.gov/23077657

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dysfunctional voltage-gated K+ channels in pulmonary artery smooth muscle cells of patients with primary pulmonary hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/23077657

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelin-1 gene suppression by shear stress: pharmacological evaluation of the role of tyrosine kinase, intracellular calcium, cytoskeleton, and mechanosensitive channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/23077657

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelin-1 is induced by cytokines in human vascular smooth muscle cells: evidence for intracellular endothelin-converting enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/23077657

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transforming growth factor-beta induces endothelin-1 expression through activation of the Smad signaling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/23077657

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelin-1-induced signaling pathways in vascular smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23077657

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mobilization of intracellular Ca(2+) by endothelin-1 in rat intrapulmonary arterial smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23077657

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0047662

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2012PLoSO...747662G

0 references

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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