(Q21134367)

P-loop containing nucleoside triphosphate hydrolase

1 reference

Rad51/DMC1/RadA, protein family

1 reference

based on heuristic

inferred from protein domain or family

DNA recombination and repair protein RecA-like, ATP-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

DNA recombination and repair protein Rad51-like, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

crossover junction endodeoxyribonuclease activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43542

2 references

DNA strand exchange activity

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43542&geneProductId=UniProtKB:O43542

single-stranded DNA binding

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43542&geneProductId=UniProtKB:O43542

8 references

8 April 2019

Identification and purification of two distinct complexes containing the five RAD51 paralogs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43542

8 April 2019

hSWS1·SWSAP1 is an evolutionarily conserved complex required for efficient homologous recombination repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43542

8 April 2019

Isolation and characterization of RAD51C, a new human member of the RAD51 family of related genes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43542

8 April 2019

Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43542

8 April 2019

A human interactome in three quantitative dimensions organized by stoichiometries and abundances

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43542

8 April 2019

XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43542

8 April 2019

HELQ promotes RAD51 paralogue-dependent repair to avert germ cell loss and tumorigenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43542

8 April 2019

Involvement of Rad51C in two distinct protein complexes of Rad51 paralogs in human cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43542

four-way junction DNA binding

IPI

1 reference

24 April 2018

Ring-shaped Rad51 paralog protein complexes bind Holliday junctions and replication forks as visualized by electron microscopy

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43542&geneProductId=UniProtKB:O43542

double-stranded DNA binding

IDA

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43542&geneProductId=UniProtKB:O43542

2 references

ATP-dependent activity, acting on DNA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43542

crossover junction endodeoxyribonuclease activity

IEA

3 references

8 April 2019

The RAD51 paralogs ensure cellular protection against mitotic defects and aneuploidy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43542

8 April 2019

RAD51C is required for Holliday junction processing in mammalian cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43542

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43542

1 reference

24 April 2018

Ring-shaped Rad51 paralog protein complexes bind Holliday junctions and replication forks as visualized by electron microscopy

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43542&geneProductId=UniProtKB:O43542

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43542

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43542

1 reference

24 April 2018

Identification and purification of two distinct complexes containing the five RAD51 paralogs

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43542&geneProductId=UniProtKB:O43542

Rad51B-Rad51C-Rad51D-XRCC2 complex

IDA

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43542&geneProductId=UniProtKB:O43542

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43542

8 April 2019

Cellular localization of human Rad51C and regulation of ubiquitin-mediated proteolysis of Rad51

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43542

8 April 2019

NUCKS1 is a novel RAD51AP1 paralog important for homologous recombination and genome stability

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43542

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43542

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43542

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43542&geneProductId=UniProtKB:O43542

response to ionizing radiation

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43542&geneProductId=UniProtKB:O43542

positive regulation of mitotic cell cycle spindle assembly checkpoint

1 reference

8 April 2019

The RAD51 paralogs ensure cellular protection against mitotic defects and aneuploidy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43542

reciprocal meiotic recombination

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43542&geneProductId=UniProtKB:O43542

regulation of centrosome duplication

1 reference

8 April 2019

The RAD51 paralogs ensure cellular protection against mitotic defects and aneuploidy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43542

resolution of mitotic recombination intermediates

1 reference

24 April 2018

The RAD51 paralogs ensure cellular protection against mitotic defects and aneuploidy

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43542&geneProductId=UniProtKB:O43542

response to organic substance

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43542

telomere maintenance via recombination

IEA

1 reference

24 April 2018

Homologous recombination generates T-loop-sized deletions at human telomeres

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43542&geneProductId=UniProtKB:O43542

4 references

8 April 2019

XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43542

8 April 2019

The XRCC2 and XRCC3 repair genes are required for chromosome stability in mammalian cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43542

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43542

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43542

meiotic DNA recombinase assembly

IEA

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43542&geneProductId=UniProtKB:O43542

interstrand cross-link repair

1 reference

8 April 2019

NUCKS1 is a novel RAD51AP1 paralog important for homologous recombination and genome stability

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43542

double-strand break repair via homologous recombination

1 reference

8 April 2019

Rad51 paralog complexes BCDX2 and CX3 act at different stages in the BRCA1-BRCA2-dependent homologous recombination pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43542

telomeric loop disassembly

1 reference

8 April 2019

A balance between elongation and trimming regulates telomere stability in stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43542

telomere maintenance via telomere trimming

TAS

1 reference

8 April 2019

A balance between elongation and trimming regulates telomere stability in stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43542

double-strand break repair via synthesis-dependent strand annealing

IGI

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43542

DNA recombination and repair protein Rad51-like, C-terminal

has part(s)

1 reference

DNA recombination and repair protein RecA-like, ATP-binding domain

1 reference

Rad51/DMC1/RadA

1 reference