(Q21135600)

Homeobox protein SIX3

1 reference

Homeobox domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Homeobox protein SIX1, N-terminal SD domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

RNA polymerase II cis-regulatory region sequence-specific DNA binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95343

sequence-specific DNA binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95343

histone deacetylase binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95343

2 references

8 April 2019

The homeotic protein Six3 is a coactivator of the nuclear receptor NOR-1 and a corepressor of the fusion protein EWS/NOR-1 in human extraskeletal myxoid chondrosarcomas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95343

8 April 2019

The homeotic protein Six3 is a coactivator of the nuclear receptor NOR-1 and a corepressor of the fusion protein EWS/NOR-1 in human extraskeletal myxoid chondrosarcomas

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95343

transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding

IPI

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95343&geneProductId=UniProtKB:O95343

transcription corepressor binding

3 references

8 April 2019

Six3 and Six6 activity is modulated by members of the groucho family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95343

8 April 2019

Direct interaction of geminin and Six3 in eye development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95343

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95343

signaling receptor binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95343

DNA-binding transcription factor activity, RNA polymerase II-specific

5 references

7 November 2018

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95343&geneProductId=UniProtKB:O95343

7 November 2018

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95343&geneProductId=UniProtKB:O95343

7 November 2018

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95343&geneProductId=UniProtKB:O95343

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95343&geneProductId=UniProtKB:O95343

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95343&geneProductId=UniProtKB:O95343

transcription cis-regulatory region binding

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95343

DNA-binding transcription activator activity, RNA polymerase II-specific

4 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95343&geneProductId=UniProtKB:O95343

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95343&geneProductId=UniProtKB:O95343

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95343&geneProductId=UniProtKB:O95343

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95343&geneProductId=UniProtKB:O95343

DNA-binding transcription factor activity, RNA polymerase II-specific

6 references

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95343

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95343

8 April 2019

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95343

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95343

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95343

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95343

3 references

transcription regulator complex

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95343

3 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95343&geneProductId=UniProtKB:O95343

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95343&geneProductId=UniProtKB:O95343

27 March 2018

Mutations in the human SIX3 gene in holoprosencephaly are loss of function

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95343&geneProductId=UniProtKB:O95343

forebrain anterior/posterior pattern specification

IDA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95343

regulation of transcription, DNA-templated

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95343

protein import into nucleus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95343

forebrain dorsal/ventral pattern formation

1 reference

8 April 2019

Mutations in the human SIX3 gene in holoprosencephaly are loss of function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95343

negative regulation of Wnt signaling pathway

IDA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95343

transcription by RNA polymerase II

1 reference

27 March 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95343&geneProductId=UniProtKB:O95343

transcription, DNA-templated

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95343&geneProductId=UniProtKB:O95343

multicellular organism development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95343

diencephalon development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95343

3 references

lens induction in camera-type eye

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95343

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95343

camera-type eye development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95343

positive regulation of transcription by RNA polymerase II

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95343

1 reference

8 April 2019

Mutations in the homeodomain of the human SIX3 gene cause holoprosencephaly

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95343

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95343

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95343

8 April 2019

Mutations in the human SIX3 gene in holoprosencephaly are loss of function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95343

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95343

4 references

8 April 2019

Mutations in the homeodomain of the human SIX3 gene cause holoprosencephaly

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95343

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95343

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95343

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95343

negative regulation of transcription, DNA-templated

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95343

8 April 2019

Mutations in the human SIX3 gene in holoprosencephaly are loss of function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95343

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95343

anatomical structure development

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95343

Homeobox protein SIX1, N-terminal SD domain

has part(s)

1 reference

Homeobox domain

1 reference