(Q21135635)

English

Structural maintenance of chromosomes flexible hinge domain containing 1

mammalian protein found in Homo sapiens

SMCHD1
SMC hinge domain-containing protein 1
structural maintenance of chromosomes flexible hinge domain-containing protein 1

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Statements

1 reference

13 November 2019

1 reference

1 December 2016

SMCs flexible hinge superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/A6NHR9

Histidine kinase/HSP90-like ATPase superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/A6NHR9

Structural maintenance of chromosomes flexible hinge domain-containing protein 1

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/A6NHR9

SMCs flexible hinge, protein family

1 reference

based on heuristic

inferred from protein domain or family

Histidine kinase/HSP90-like ATPase family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A6NHR9

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A6NHR9

1 reference

8 April 2019

Human inactive X chromosome is compacted through a PRC2-independent SMCHD1-HBiX1 pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A6NHR9

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A6NHR9

2 references

1 reference

5 June 2018

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=A6NHR9&geneProductId=UniProtKB:A6NHR9

determination method

IEA

site of double-strand break

determination method

IDA

biological process

dosage compensation by inactivation of X chromosome

1 reference

5 June 2018

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=A6NHR9&geneProductId=UniProtKB:A6NHR9

determination method

IEA

chromosome organization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A6NHR9

double-strand break repair

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A6NHR9

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A6NHR9

determination method

IEA

chromatin organization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A6NHR9

determination method

IEA

cellular response to DNA damage stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A6NHR9

determination method

IEA

positive regulation of DNA repair

1 reference

8 April 2019

SMCHD1 accumulates at DNA damage sites and facilitates the repair of DNA double-strand breaks

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A6NHR9

determination method

IMP

negative regulation of double-strand break repair via homologous recombination

1 reference

8 April 2019

Structural maintenance of chromosomes flexible hinge domain containing 1 (SMCHD1) promotes non-homologous end joining and inhibits homologous recombination repair upon DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A6NHR9

determination method

IMP

positive regulation of double-strand break repair via nonhomologous end joining

1 reference

8 April 2019

Structural maintenance of chromosomes flexible hinge domain containing 1 (SMCHD1) promotes non-homologous end joining and inhibits homologous recombination repair upon DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A6NHR9

1 reference

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/A6NHR9

Histidine kinase/HSP90-like ATPase domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/A6NHR9

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

(Q21135635)

Structural maintenance of chromosomes flexible hinge domain containing 1

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