(Q21135641)

http://www.ebi.ac.uk/interpro/protein/Q8IY18

P-loop containing nucleoside triphosphate hydrolase

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8IY18

RecF/RecN/SMC, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IY18

5 references

8 April 2019

Characterization of a novel human SMC heterodimer homologous to the Schizosaccharomyces pombe Rad18/Spr18 complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IY18

8 April 2019

DNA repair. Proteomics reveals dynamic assembly of repair complexes during bypass of DNA cross-links

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IY18

8 April 2019

Identification of the proteins, including MAGEG1, that make up the human SMC5-6 protein complex

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IY18

8 April 2019

Composition and architecture of the Schizosaccharomyces pombe Rad18 (Smc5-6) complex

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IY18

8 April 2019

A human interactome in three quantitative dimensions organized by stoichiometries and abundances

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IY18

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IY18

site of double-strand break

cell component

1 reference

8 April 2019

DNA repair. Proteomics reveals dynamic assembly of repair complexes during bypass of DNA cross-links

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IY18

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IY18

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IY18

8 April 2019

The SMC5/6 complex maintains telomere length in ALT cancer cells through SUMOylation of telomere-binding proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IY18

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IY18

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IY18

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IY18

8 April 2019

The SMC5/6 complex maintains telomere length in ALT cancer cells through SUMOylation of telomere-binding proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IY18

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IY18

Characterization of a novel human SMC heterodimer homologous to the Schizosaccharomyces pombe Rad18/Spr18 complex

IDA

interchromatin granule

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IY18

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IY18

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IY18

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IY18

8 April 2019

Characterization of a novel human SMC heterodimer homologous to the Schizosaccharomyces pombe Rad18/Spr18 complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IY18

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IY18

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IY18

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IY18

positive regulation of maintenance of mitotic sister chromatid cohesion

1 reference

8 April 2019

SMC5 and MMS21 are required for chromosome cohesion and mitotic progression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IY18

cellular response to DNA damage stimulus

IMP

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IY18

8 April 2019

Characterization of a novel human SMC heterodimer homologous to the Schizosaccharomyces pombe Rad18/Spr18 complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IY18

8 April 2019

DNA repair. Proteomics reveals dynamic assembly of repair complexes during bypass of DNA cross-links

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IY18

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IY18

telomere maintenance via recombination

1 reference

8 April 2019

The SMC5/6 complex maintains telomere length in ALT cancer cells through SUMOylation of telomere-binding proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IY18

1 reference

8 April 2019

The SMC5/6 complex maintains telomere length in ALT cancer cells through SUMOylation of telomere-binding proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IY18

positive regulation of chromosome segregation

IMP

1 reference

8 April 2019

DNA repair. Proteomics reveals dynamic assembly of repair complexes during bypass of DNA cross-links

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IY18

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IY18

double-strand break repair via nonhomologous end joining

1 reference

8 April 2019

Human SMC5/6 complex promotes sister chromatid homologous recombination by recruiting the SMC1/3 cohesin complex to double-strand breaks

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IY18

2 references

sister chromatid cohesion

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IY18

RecF/RecN/SMC, N-terminal

has part(s)

1 reference

stated in

InterPro Release 71.0