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(Q21136592)
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English
WD repeat domain 59
mammalian protein found in Homo sapiens
CDw12 antigen
WDR59
GATOR complex protein WDR59
WD repeat-containing protein 59
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q6PJI9
part of
membrane protein
1 reference
based on heuristic
inferred from GOA cell component → membrane
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q6PJI9
encoded by
WDR59
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q6PJI9
molecular function
protein binding
determination method
IPI
3 references
retrieved
8 April 2019
stated in
The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway
GOA
curator
UniProt
UniProt protein ID
Q6PJI9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PJI9
determination method
IPI
retrieved
8 April 2019
stated in
SZT2 dictates GATOR control of mTORC1 signalling.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PJI9
determination method
IPI
retrieved
8 April 2019
stated in
The Sestrins interact with GATOR2 to negatively regulate the amino-acid-sensing pathway upstream of mTORC1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PJI9
determination method
IPI
cell component
lysosome
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q6PJI9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PJI9
determination method
IEA
lysosomal membrane
determination method
IDA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q6PJI9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PJI9
determination method
IEA
retrieved
8 April 2019
stated in
KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1
GOA
curator
UniProt
UniProt protein ID
Q6PJI9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PJI9
determination method
IDA
membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q6PJI9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PJI9
determination method
IEA
GATOR2 complex
determination method
IDA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PJI9
determination method
IEA
retrieved
8 April 2019
stated in
A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PJI9
determination method
IDA
biological process
cellular response to amino acid starvation
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1
GOA
curator
UniProt
UniProt protein ID
Q6PJI9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PJI9
determination method
IMP
positive regulation of TOR signaling
determination method
IEA
IMP
2 references
retrieved
8 April 2019
stated in
A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PJI9
determination method
IMP
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6PJI9
determination method
IEA
Identifiers
RefSeq protein ID
NP_001311100
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
79726
NP_001311101
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
79726
NP_085058
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
79726
XP_005256203
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
79726
XP_011521634
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
79726
XP_016879156
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
79726
XP_016879157
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
79726
XP_016879158
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
79726
XP_016879159
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
79726
XP_024306213
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
79726
XP_024306214
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
79726
UniProt protein ID
Q6PJI9
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q6PJI9
Ensembl protein ID
ENSP00000262144
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000262144
ENSP00000482446
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000482446
ENSP00000454382
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000454382
ENSP00000455060
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000455060
ENSP00000456139
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000456139
ENSP00000457605
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000457605
ENSP00000457978
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000457978
ENSP00000481730
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000481730
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