(Q21140224)

http://www.ebi.ac.uk/interpro/protein/Q99081

Myc-type, basic helix-loop-helix (bHLH) domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

protein dimerization activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

protein homodimerization activity

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

DNA-binding transcription factor activity

IBA

1 reference

27 March 2018

Human Hand1 basic helix-loop-helix (bHLH) protein: extra-embryonic expression pattern, interaction partners and identification of its transcriptional repressor domains

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99081&geneProductId=UniProtKB:Q99081

HMG box domain binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

DNA-binding transcription activator activity, RNA polymerase II-specific

2 references

10 September 2018

Human Hand1 basic helix-loop-helix (bHLH) protein: extra-embryonic expression pattern, interaction partners and identification of its transcriptional repressor domains

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99081&geneProductId=UniProtKB:Q99081

8 April 2019

Human Hand1 basic helix-loop-helix (bHLH) protein: extra-embryonic expression pattern, interaction partners and identification of its transcriptional repressor domains

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

transcription factor binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

RNA polymerase II cis-regulatory region sequence-specific DNA binding

IPI

1 reference

27 March 2018

Human Hand1 basic helix-loop-helix (bHLH) protein: extra-embryonic expression pattern, interaction partners and identification of its transcriptional repressor domains

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99081&geneProductId=UniProtKB:Q99081

bHLH transcription factor binding

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99081&geneProductId=UniProtKB:Q99081

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

10 references

8 April 2019

Mutations affecting the BHLHA9 DNA-binding domain cause MSSD, mesoaxial synostotic syndactyly with phalangeal reduction, Malik-Percin type

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

8 April 2019

The protein ENH is a cytoplasmic sequestration factor for Id2 in normal and tumor cells from the nervous system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

8 April 2019

Differential genomic targeting of the transcription factor TAL1 in alternate haematopoietic lineages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

8 April 2019

Next-generation sequencing to generate interactome datasets

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

8 April 2019

A proteome-scale map of the human interactome network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

8 April 2019

Gene deregulation and spatial genome reorganization near breakpoints prior to formation of translocations in anaplastic large cell lymphoma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

8 April 2019

SCL binds the human homologue of DRG in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

8 April 2019

LSD1-mediated epigenetic modification is required for TAL1 function and hematopoiesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

8 April 2019

Human Hand1 basic helix-loop-helix (bHLH) protein: extra-embryonic expression pattern, interaction partners and identification of its transcriptional repressor domains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

cAMP response element binding

IPI

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

DNA-binding transcription factor activity, RNA polymerase II-specific

3 references

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

8 April 2019

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

RNA polymerase II cis-regulatory region sequence-specific DNA binding

ISA

IBA

DNA-binding transcription factor activity

2 references

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

transcription regulator complex

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99081&geneProductId=UniProtKB:Q99081

RNA polymerase II transcription regulator complex

1 reference

8 April 2019

Human Hand1 basic helix-loop-helix (bHLH) protein: extra-embryonic expression pattern, interaction partners and identification of its transcriptional repressor domains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

4 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99081&geneProductId=UniProtKB:Q99081

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99081&geneProductId=UniProtKB:Q99081

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99081&geneProductId=UniProtKB:Q99081

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99081&geneProductId=UniProtKB:Q99081

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

intracellular membrane-bounded organelle

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

regulation of transcription, DNA-templated

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99081&geneProductId=UniProtKB:Q99081

regulation of transcription by RNA polymerase II

1 reference

8 April 2019

Distinguishable patterns of protein-DNA interactions involving complexes of basic helix-loop-helix proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

HEB, a Helix-Loop-Helix Protein Related to E2A and ITF2 That Can Modulate the DNA-Binding Ability of Myogenic Regulatory Factors

muscle organ development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

transcription, DNA-templated

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99081&geneProductId=UniProtKB:Q99081

nervous system development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

multicellular organism development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

positive regulation of transcription, DNA-templated

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

positive regulation of gene expression

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

1 reference

8 April 2019

HEB, a Helix-Loop-Helix Protein Related to E2A and ITF2 That Can Modulate the DNA-Binding Ability of Myogenic Regulatory Factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

positive regulation of transcription by RNA polymerase II

2 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99081&geneProductId=UniProtKB:Q99081

27 March 2018

Human Hand1 basic helix-loop-helix (bHLH) protein: extra-embryonic expression pattern, interaction partners and identification of its transcriptional repressor domains

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99081&geneProductId=UniProtKB:Q99081

transcription by RNA polymerase II

1 reference

27 March 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q99081&geneProductId=UniProtKB:Q99081

regulation of hematopoietic stem cell differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

positive regulation of transcription by RNA polymerase II

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

8 April 2019

Human Hand1 basic helix-loop-helix (bHLH) protein: extra-embryonic expression pattern, interaction partners and identification of its transcriptional repressor domains

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99081

physically interacts with

IBA

1 reference

https://thebiogrid.org/news/227

retrieved

19 April 2020

stated in

BioGRID

A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing

has part(s)

Myc-type, basic helix-loop-helix (bHLH) domain

1 reference

stated in

InterPro Release 71.0