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SOS Ras/Rho guanine nucleotide exchange factor 2
mammalian protein found in Homo sapiens
son of sevenless homolog 2
SOS2
guanine nucleotide releasing factor
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q07890
subclass of
protein
1 reference
stated in
UniProt
retrieved
1 December 2016
UniProt protein ID
Q07890
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q07890
encoded by
SOS2
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q07890
molecular function
protein heterodimerization activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07890
determination method
IEA
DNA binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07890
determination method
IEA
protein binding
determination method
IPI
7 references
retrieved
8 April 2019
stated in
Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07890
determination method
IPI
retrieved
8 April 2019
stated in
Differential interactions of human Sos1 and Sos2 with Grb2
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07890
determination method
IPI
retrieved
8 April 2019
stated in
A novel proteomic screen for peptide-protein interactions
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07890
determination method
IPI
retrieved
8 April 2019
stated in
Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07890
determination method
IPI
retrieved
8 April 2019
stated in
A human MAP kinase interactome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07890
determination method
IPI
retrieved
8 April 2019
stated in
Toward an understanding of the protein interaction network of the human liver
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07890
determination method
IPI
retrieved
8 April 2019
stated in
Charting the molecular network of the drug target Bcr-Abl
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07890
determination method
IPI
guanyl-nucleotide exchange factor activity
determination method
IEA
TAS
3 references
retrieved
7 November 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07890&geneProductId=UniProtKB:Q07890
determination method
TAS
retrieved
7 November 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q07890
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07890&geneProductId=UniProtKB:Q07890
determination method
IEA
retrieved
7 November 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07890&geneProductId=UniProtKB:Q07890
determination method
IEA
guanyl-nucleotide exchange factor activity
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q07890
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07890
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07890
determination method
IEA
cell component
cytosol
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07890
determination method
TAS
nucleosome
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07890
determination method
IEA
biological process
positive regulation of small GTPase mediated signal transduction
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07890
determination method
IEA
regulation of Rho protein signal transduction
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07890
determination method
IEA
regulation of small GTPase mediated signal transduction
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07890
determination method
TAS
positive regulation of apoptotic process
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07890
determination method
TAS
small GTPase mediated signal transduction
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07890
determination method
IEA
G protein-coupled receptor signaling pathway
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07890
determination method
TAS
Identifiers
RefSeq protein ID
NP_008870
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
6655
UniProt protein ID
Q07890
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q07890
Ensembl protein ID
ENSP00000216373
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000216373
ENSP00000445328
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000445328
ENSP00000452553
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000452553
ENSP00000484766
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000484766
PDB structure ID
1GBR
1 reference
stated in
Swiss-Prot
UniProt
retrieved
9 November 2015
reference URL
http://www.uniprot.org/uniprot/Q02384.txt?version=129
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