(Q21154919)

http://www.ebi.ac.uk/interpro/protein/P34947

Protein kinase-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P34947

RGS domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P34947

membrane protein

1 reference

inferred from GOA cell component → membrane

regulator of G protein signalling

1 reference

AGC-kinase, C-terminal domain, protein family

1 reference

Protein kinase domain, protein family

1 reference

Protein kinase, ATP binding site, protein family

1 reference

1 reference

13 November 2019

1 reference

13 November 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947

1 reference

8 April 2019

nucleotide binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947

1 reference

8 April 2019

protein kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947

1 reference

8 April 2019

kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947

1 reference

8 April 2019

protein serine/threonine kinase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947

8 April 2019

8 April 2019

G-protein-coupled receptor kinase 5 phosphorylates p53 and inhibits DNA damage-induced apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947

protein binding

4 references

8 April 2019

G-protein-coupled receptor kinase 5 phosphorylates p53 and inhibits DNA damage-induced apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947

8 April 2019

The G-protein-coupled receptor kinase 5 inhibits NFkappaB transcriptional activity by inducing nuclear accumulation of IkappaB alpha

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947

8 April 2019

Beta-arrestin1 phosphorylation by GRK5 regulates G protein-independent 5-HT4 receptor signalling

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947

8 April 2019

Characterization of G-protein coupled receptor kinase interaction with the neurokinin-1 receptor using bioluminescence resonance energy transfer

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947

phospholipid binding

1 reference

8 April 2019

Structure-function analysis of G protein-coupled receptor kinase-5. Role of the carboxyl terminus in kinase regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947

protein kinase C binding

1 reference

8 April 2019

Structure-function analysis of G protein-coupled receptor kinase-5. Role of the carboxyl terminus in kinase regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947

lipid binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947

1 reference

8 April 2019

cell component

nuclear membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947

1 reference

8 April 2019

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947

1 reference

8 April 2019

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947

8 April 2019

8 April 2019

A predicted amphipathic helix mediates plasma membrane localization of GRK5

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947

8 April 2019

8 April 2019

Characterization of G-protein coupled receptor kinase interaction with the neurokinin-1 receptor using bioluminescence resonance energy transfer

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947

1 reference

8 April 2019

cytosol

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947

1 reference

8 April 2019

nuclear speck

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947

1 reference

8 April 2019

biological process

phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947

1 reference

8 April 2019

adenylate cyclase-modulating G protein-coupled receptor signaling pathway

1 reference

8 April 2019

Involvement of G protein-coupled receptor kinase 5 in homologous desensitization of the thyrotropin receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947

negative regulation of apoptotic process

1 reference

8 April 2019

G-protein-coupled receptor kinase 5 phosphorylates p53 and inhibits DNA damage-induced apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947

Wnt signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947

1 reference

8 April 2019

tachykinin receptor signaling pathway

1 reference

8 April 2019

Characterization of G-protein coupled receptor kinase interaction with the neurokinin-1 receptor using bioluminescence resonance energy transfer

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947

regulation of cell cycle

1 reference

8 April 2019

G-protein coupled receptor kinase 5 regulates prostate tumor growth

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947

protein phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947

1 reference

8 April 2019

positive regulation of cell population proliferation

1 reference

8 April 2019

G-protein coupled receptor kinase 5 regulates prostate tumor growth

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947

protein autophosphorylation

1 reference

8 April 2019

A predicted amphipathic helix mediates plasma membrane localization of GRK5

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947

fat cell differentiation

Ensembl genome database project

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947

signal transduction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947

1 reference

8 April 2019

apoptotic process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947

1 reference

8 April 2019

regulation of G protein-coupled receptor signaling pathway

1 reference

8 April 2019

Expression, purification, and characterization of the G protein-coupled receptor kinase GRK5

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947

G protein-coupled receptor signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34947

1 reference

8 April 2019

D08.811.913.696.620.682.700.364.775

Identifiers

MeSH descriptor ID

D054774

subject named as

G-Protein-Coupled Receptor Kinase 5

0 references

MeSH tree code

0 references

D12.776.476.563.364.775

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

9 August 2016

language of work or name

1 reference

9 August 2016

language of work or name

1 reference

inferred by common MeSH mappings on source and on Wikidata

UMLS 2023