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(Q21156265)
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Docking protein 2
mammalian protein found in Homo sapiens
docking protein 2, 56kDa
docking protein 2
downstream of tyrosine kinase 2
p56(dok-2)
DOK2
docking protein 2, 56kD
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
O60496
subclass of
protein
1 reference
stated in
UniProt
retrieved
1 December 2016
UniProt protein ID
O60496
part of
PH-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O60496
pleckstrin homology domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Dok1/2/3, PTB domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
IRS-type PTB domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
O60496
encoded by
DOK2
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
O60496
molecular function
protein binding
determination method
IPI
1 reference
retrieved
8 April 2019
stated in
Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60496
determination method
IPI
transmembrane receptor protein tyrosine kinase adaptor activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60496
determination method
IEA
cell component
cytosol
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60496
determination method
TAS
biological process
cell surface receptor signaling pathway
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
Evidence that Llck-mediated phosphorylation of p56dok and p62dok may play a role in CD2 signaling
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60496
determination method
TAS
Ras protein signal transduction
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60496
determination method
IEA
leukocyte migration
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60496
determination method
TAS
signal transduction
determination method
TAS
2 references
retrieved
8 April 2019
stated in
Evidence that Llck-mediated phosphorylation of p56dok and p62dok may play a role in CD2 signaling
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60496
determination method
TAS
retrieved
8 April 2019
stated in
Molecular cloning and characterization of p56dok-2 defines a new family of RasGAP-binding proteins
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60496
determination method
TAS
transmembrane receptor protein tyrosine kinase signaling pathway
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60496
determination method
IEA
axon guidance
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60496
determination method
TAS
has part(s)
pleckstrin homology domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O60496
IRS-type PTB domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O60496
Dok1/2/3, PTB domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O60496
Identifiers
RefSeq protein ID
NP_001304729
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
9046
NP_003965
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
9046
NP_958728
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
9046
XP_005273737
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
9046
UniProt protein ID
O60496
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
O60496
Ensembl protein ID
ENSP00000276420
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000276420
ENSP00000429224
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000429224
ENSP00000429508
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000429508
ENSP00000430729
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000430729
PDB structure ID
2D9W
1 reference
stated in
UniProt
UniProt protein ID
O60496
retrieved
9 August 2016
language of work or name
English
2DLW
1 reference
stated in
UniProt
UniProt protein ID
O60496
retrieved
9 August 2016
language of work or name
English
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