(Q21156571)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P63027

synaptosomal vesicle fusion pore

1 reference

Transporter Classification Database ID

1.F.1.1.1

hierarchical database ID heuristic

2 October 2019

based on heuristic

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Synaptobrevin

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

SNAP receptor activity

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63027&geneProductId=UniProtKB:P63027

The synaptic vesicle cycle

IBA

protein self-association

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

11 references

8 April 2019

SUMOylation of Syntaxin1A regulates presynaptic endocytosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

8 April 2019

WD-repeat-propeller-FYVE protein, ProF, binds VAMP2 and protein kinase Czeta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

8 April 2019

A role for the CHC22 clathrin heavy-chain isoform in human glucose metabolism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

8 April 2019

Molecular cloning and characterization of mammalian homologues of vesicle-associated membrane protein-associated (VAMP-associated) proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

8 April 2019

The molecular basis for the endocytosis of small R-SNAREs by the clathrin adaptor CALM

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

8 April 2019

Mode of VAMP substrate recognition and inhibition of Clostridium botulinum neurotoxin F

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

8 April 2019

Protein kinase D 3 is localized in vesicular structures and interacts with vesicle-associated membrane protein 2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

8 April 2019

A proteome-scale map of the human interactome network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

8 April 2019

Discovery of a novel enzymatic cleavage site for botulinum neurotoxin F5

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

8 April 2019

The molecular basis for the endocytosis of small R-SNAREs by the clathrin adaptor CALM

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

8 April 2019

NMR analysis of the structure of synaptobrevin and of its interaction with syntaxin

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

calcium-dependent protein binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

1 January 2018

Syntaxin 4 and Synip (syntaxin 4 interacting protein) regulate insulin secretion in the pancreatic beta HC-9 cell

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

clathrin-sculpted monoamine transport vesicle membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

8 April 2019

A critical role for vesicle-associated membrane protein-7 in exocytosis from human eosinophils and neutrophils

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

8 April 2019

Different effects of Sec61α, Sec62 and Sec63 depletion on transport of polypeptides into the endoplasmic reticulum of mammalian cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

integral component of plasma membrane

1 reference

8 April 2019

Structures and chromosomal localizations of two human genes encoding synaptobrevins 1 and 2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

synaptic vesicle membrane

zymogen granule membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

A role for the CHC22 clathrin heavy-chain isoform in human glucose metabolism

IEA

clathrin-coated vesicle

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

clathrin-sculpted glutamate transport vesicle membrane

IDA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

intracellular membrane-bounded organelle

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

synaptobrevin 2-SNAP-25-syntaxin-1a complex

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

4 references

8 April 2019

Genetics of synaptic vesicle function: toward the complete functional anatomy of an organelle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

8 April 2019

Ca2+-dependent Phosphorylation of Syntaxin-1A by the Death-associated Protein (DAP) Kinase Regulates Its Interaction with Munc18

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

8 April 2019

Vesicle-associated membrane protein 3 (VAMP-3) and VAMP-8 are present in human platelets and are required for granule secretion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

8 April 2019

The dysbindin-containing complex (BLOC-1) in brain: developmental regulation, interaction with SNARE proteins and role in neurite outgrowth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex

IDA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

voltage-gated potassium channel complex

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

1 reference

8 April 2019

WD-repeat-propeller-FYVE protein, ProF, binds VAMP2 and protein kinase Czeta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

perinuclear region of cytoplasm

IDA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

neuron projection terminus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

clathrin-coated vesicle membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

natural killer cell degranulation

biological process

1 reference

8 April 2019

Vesicle-associated membrane protein 7 (VAMP-7) is essential for target cell killing in a natural killer cell line

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

1 reference

8 April 2019

VAMP8 is a vesicle SNARE that regulates mucin secretion in airway goblet cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

regulation of histamine secretion by mast cell

IMP

1 reference

8 April 2019

Vesicle associated membrane protein (VAMP)-7 and VAMP-8, but not VAMP-2 or VAMP-3, are required for activation-induced degranulation of mature human mast cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

A critical role for vesicle-associated membrane protein-7 in exocytosis from human eosinophils and neutrophils

IMP

neutrophil degranulation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P63027&geneProductId=UniProtKB:P63027

A critical role for vesicle-associated membrane protein-7 in exocytosis from human eosinophils and neutrophils

IBA

eosinophil degranulation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

1 reference

8 April 2019

Genetics of synaptic vesicle function: toward the complete functional anatomy of an organelle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

regulation of delayed rectifier potassium channel activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

calcium-ion regulated exocytosis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

regulation of exocytosis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

positive regulation of intracellular protein transport

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

Golgi to plasma membrane protein transport

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

cellular response to insulin stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

long-term potentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

regulation of vesicle-mediated transport

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

membrane organization

1 reference

8 April 2019

protein-containing complex assembly

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

post-Golgi vesicle-mediated transport

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

neurotransmitter secretion

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63027

physically interacts with

botulinum toxin Type B

object has role

reaction inhibitor

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1201569

has part(s)

Synaptobrevin domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P63027

Commons category

Vesicle-associated membrane protein 2

0 references

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

1 reference

4 August 2016

Transporter Classification Database ID

English

1.F.1.1.1

2 references

Transporter Classification database

13 March 2020

Transporter Classification database