(Q21159914)

Tissue inhibitor of metalloproteinases-like, OB-fold

1 reference

Secreted frizzled-related protein 4

1 reference

Frizzled domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Netrin module, non-TIMP type, protein family

1 reference

based on heuristic

inferred from protein domain or family

Netrin domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

Systematic identification of hepatocellular proteins interacting with NS5A of the hepatitis C virus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6FHJ7

3 references

27 March 2018

Wnt signaling in midbrain dopaminergic neuron development and regenerative medicine for Parkinson's disease

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6FHJ7&geneProductId=UniProtKB:Q6FHJ7

27 March 2018

Wnt3a binds to several sFRPs in the nanomolar range

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6FHJ7&geneProductId=UniProtKB:Q6FHJ7

27 March 2018

Wnt3a binds to several sFRPs in the nanomolar range

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6FHJ7&geneProductId=UniProtKB:Q6FHJ7

G protein-coupled receptor activity

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6FHJ7&geneProductId=UniProtKB:Q6FHJ7

Wnt-activated receptor activity

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6FHJ7&geneProductId=UniProtKB:Q6FHJ7

4 references

8 April 2019

Wnt signaling in midbrain dopaminergic neuron development and regenerative medicine for Parkinson's disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6FHJ7

8 April 2019

Wnt3a binds to several sFRPs in the nanomolar range

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6FHJ7

8 April 2019

Wnt3a binds to several sFRPs in the nanomolar range

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6FHJ7

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6FHJ7

3 references

27 March 2018

Expression of frizzled-related protein and Wnt-signalling molecules in invasive human breast tumours

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6FHJ7&geneProductId=UniProtKB:Q6FHJ7

27 March 2018

Membranous expression of secreted frizzled-related protein 4 predicts for good prognosis in localized prostate cancer and inhibits PC3 cellular proliferation in vitro

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6FHJ7&geneProductId=UniProtKB:Q6FHJ7

27 March 2018

Secreted Frizzled related protein-4 (sFRP4) promotes epidermal differentiation and apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6FHJ7&geneProductId=UniProtKB:Q6FHJ7

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6FHJ7

1 reference

8 April 2019

Membranous expression of secreted frizzled-related protein 4 predicts for good prognosis in localized prostate cancer and inhibits PC3 cellular proliferation in vitro

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6FHJ7

1 reference

8 April 2019

Secreted Frizzled related protein-4 (sFRP4) promotes epidermal differentiation and apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6FHJ7

1 reference

27 March 2018

Membranous expression of secreted frizzled-related protein 4 predicts for good prognosis in localized prostate cancer and inhibits PC3 cellular proliferation in vitro

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6FHJ7&geneProductId=UniProtKB:Q6FHJ7

integral component of membrane

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6FHJ7&geneProductId=UniProtKB:Q6FHJ7

4 references

8 April 2019

Expression of frizzled-related protein and Wnt-signalling molecules in invasive human breast tumours

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6FHJ7

8 April 2019

Membranous expression of secreted frizzled-related protein 4 predicts for good prognosis in localized prostate cancer and inhibits PC3 cellular proliferation in vitro

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6FHJ7

8 April 2019

Secreted Frizzled related protein-4 (sFRP4) promotes epidermal differentiation and apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6FHJ7

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6FHJ7

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6FHJ7

positive regulation of keratinocyte apoptotic process

1 reference

8 April 2019

Secreted Frizzled related protein-4 (sFRP4) promotes epidermal differentiation and apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6FHJ7

positive regulation of receptor internalization

1 reference

8 April 2019

Secreted frizzled-related protein-4 reduces sodium-phosphate co-transporter abundance and activity in proximal tubule cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6FHJ7

positive regulation of canonical Wnt signaling pathway

1 reference

8 April 2019

Differential effects of secreted frizzled-related proteins (sFRPs) on osteoblastic differentiation of mouse mesenchymal cells and apoptosis of osteoblasts

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6FHJ7

negative regulation of Wnt signaling pathway

IGI

1 reference

8 April 2019

Wnt signaling in midbrain dopaminergic neuron development and regenerative medicine for Parkinson's disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6FHJ7

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6FHJ7

NAS

Wnt signaling pathway

1 reference

8 April 2019

negative regulation of DNA-binding transcription factor activity

1 reference

8 April 2019

Increased expression of secreted frizzled-related protein 4 in polycystic kidneys

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6FHJ7

multicellular organism development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6FHJ7

positive regulation of gene expression

1 reference

8 April 2019

Secreted Frizzled related protein-4 (sFRP4) promotes epidermal differentiation and apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6FHJ7

positive regulation of apoptotic process

1 reference

8 April 2019

Secreted frizzled-related protein 4 is silenced by hypermethylation and induces apoptosis in beta-catenin-deficient human mesothelioma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6FHJ7

1 reference

8 April 2019

Differential expression of frpHE: a novel human stromal protein of the secreted frizzled gene family, during the endometrial cycle and malignancy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6FHJ7

positive regulation of epidermal cell differentiation

NAS

1 reference

8 April 2019

Secreted Frizzled related protein-4 (sFRP4) promotes epidermal differentiation and apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6FHJ7

negative regulation of cell population proliferation

2 references

8 April 2019

Membranous expression of secreted frizzled-related protein 4 predicts for good prognosis in localized prostate cancer and inhibits PC3 cellular proliferation in vitro

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6FHJ7

8 April 2019

Secreted frizzled-related protein 4 is silenced by hypermethylation and induces apoptosis in beta-catenin-deficient human mesothelioma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6FHJ7

negative regulation of canonical Wnt signaling pathway

IMP

4 references

27 March 2018

Membranous expression of secreted frizzled-related protein 4 predicts for good prognosis in localized prostate cancer and inhibits PC3 cellular proliferation in vitro

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6FHJ7&geneProductId=UniProtKB:Q6FHJ7

27 March 2018

Secreted frizzled-related protein 4 is silenced by hypermethylation and induces apoptosis in beta-catenin-deficient human mesothelioma cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6FHJ7&geneProductId=UniProtKB:Q6FHJ7

27 March 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6FHJ7&geneProductId=UniProtKB:Q6FHJ7

27 March 2018

Increased expression of secreted frizzled-related protein 4 in polycystic kidneys

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6FHJ7&geneProductId=UniProtKB:Q6FHJ7

G protein-coupled receptor signaling pathway

1 reference

27 March 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6FHJ7&geneProductId=UniProtKB:Q6FHJ7

non-canonical Wnt signaling pathway

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6FHJ7

canonical Wnt signaling pathway

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6FHJ7

negative regulation of canonical Wnt signaling pathway

5 references

8 April 2019

Membranous expression of secreted frizzled-related protein 4 predicts for good prognosis in localized prostate cancer and inhibits PC3 cellular proliferation in vitro

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6FHJ7

8 April 2019

Secreted frizzled-related protein 4 is silenced by hypermethylation and induces apoptosis in beta-catenin-deficient human mesothelioma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6FHJ7

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6FHJ7

8 April 2019

Increased expression of secreted frizzled-related protein 4 in polycystic kidneys

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6FHJ7

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6FHJ7

Netrin module, non-TIMP type

has part(s)

1 reference

Netrin domain

1 reference

frizzled domain

1 reference