Wikidata

(Q21171851)

English

WD repeat domain 5

mammalian protein found in Homo sapiens

  • BMP2-induced 3-kb gene protein
  • WD repeat-containing protein 5
  • SWD3, Set1c WD40 repeat protein, homolog
  • WDR5
  • cilia and flagella associated protein 89
In more languages

Statements

molecular function
protein binding
determination method
IPI
29 references
retrieved
8 April 2019
stated in
CHD8 is an ATP-dependent chromatin remodeling factor that regulates beta-catenin target genes
GOA
curator
UniProt
UniProt protein ID
P61964
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964
determination method
IPI
retrieved
8 April 2019
stated in
Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1
GOA
curator
UniProt
UniProt protein ID
P61964
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964
determination method
IPI
retrieved
8 April 2019
stated in
On the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complex
GOA
curator
UniProt
UniProt protein ID
P61964
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964
determination method
IPI
retrieved
8 April 2019
stated in
Wdr82 is a C-terminal domain-binding protein that recruits the Setd1A Histone H3-Lys4 methyltransferase complex to transcription start sites of transcribed human genes
GOA
curator
UniProt
UniProt protein ID
P61964
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964
determination method
IPI
retrieved
8 April 2019
stated in
Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964
determination method
IPI
retrieved
8 April 2019
stated in
PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964
determination method
IPI
retrieved
8 April 2019
stated in
CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964
determination method
IPI
retrieved
8 April 2019
stated in
Structural analysis of the KANSL1/WDR5/KANSL2 complex reveals that WDR5 is required for efficient assembly and chromatin targeting of the NSL complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964
determination method
IPI
retrieved
8 April 2019
stated in
Knockdown of ALR (MLL2) reveals ALR target genes and leads to alterations in cell adhesion and growth
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964
determination method
IPI
retrieved
8 April 2019
stated in
WDR5 is essential for assembly of the VISA-associated signaling complex and virus-triggered IRF3 and NF-kappaB activation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964
determination method
IPI
retrieved
8 April 2019
stated in
The BRCT-domain containing protein PTIP links PAX2 to a histone H3, lysine 4 methyltransferase complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964
determination method
IPI
retrieved
8 April 2019
stated in
SET1 and p300 act synergistically, through coupled histone modifications, in transcriptional activation by p53
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964
determination method
IPI
retrieved
8 April 2019
stated in
A tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964
determination method
IPI
retrieved
8 April 2019
stated in
Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964
determination method
IPI
retrieved
8 April 2019
stated in
WDR5 interacts with mixed lineage leukemia (MLL) protein via the histone H3-binding pocket
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964
determination method
IPI
retrieved
8 April 2019
stated in
Structural basis for molecular recognition and presentation of histone H3 by WDR5
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964
determination method
IPI
retrieved
8 April 2019
stated in
Towards a proteome-scale map of the human protein–protein interaction network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964
determination method
IPI
retrieved
8 April 2019
stated in
Regulation of transcription by the MLL2 complex and MLL complex-associated AKAP95.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964
determination method
IPI
retrieved
8 April 2019
stated in
Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964
determination method
IPI
retrieved
8 April 2019
stated in
Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964
determination method
IPI
retrieved
8 April 2019
stated in
On the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964
determination method
IPI
retrieved
8 April 2019
stated in
Regulation of HOXA2 gene expression by the ATP-dependent chromatin remodeling enzyme CHD8
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964
determination method
IPI
retrieved
8 April 2019
stated in
Phosphorylation of MLL by ATR is required for execution of mammalian S-phase checkpoint
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964
determination method
IPI
retrieved
8 April 2019
stated in
Coactivator as a target gene specificity determinant for histone H3 lysine 4 methyltransferases
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964
determination method
IPI
retrieved
8 April 2019
stated in
Structural and biochemical insights into MLL1 core complex assembly
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964
determination method
IPI
retrieved
8 April 2019
stated in
A High-Density Map for Navigating the Human Polycomb Complexome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964
determination method
IPI
retrieved
8 April 2019
stated in
Dynamic circadian protein-protein interaction networks predict temporal organization of cellular functions
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964
determination method
IPI
retrieved
8 April 2019
stated in
Crosstalk between leukemia-associated proteins MOZ and MLL regulates HOX gene expression in human cord blood CD34+ cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964
determination method
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61964
determination method
IPI
cell component
biological process

Identifiers

PDB structure ID
 
edit
    edit
      edit
        edit
          edit
            edit
              edit
                edit
                  edit
                    Retrieved from "https://www.wikidata.org/w/index.php?title=Q21171851&oldid=2023034501"