Wikidata

(Q21172231)

English

Serine and arginine rich splicing factor 1

mammalian protein found in Homo sapiens

  • SRSF1
  • ASF-1
  • SR splicing factor 1
  • alternative-splicing factor 1
  • pre-mRNA-splicing factor SF2, P33 subunit
  • Splicing factor, arginine/serine-rich 1
  • serine/arginine-rich splicing factor 1
  • splicing factor, arginine/serine-rich, 30-KD, A
  • splicing factor 2
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No label defined

No description defined

Statements

molecular function
protein binding
determination method
IPI
15 references
retrieved
8 April 2019
stated in
A novel SR-related protein is required for the second step of Pre-mRNA splicing
GOA
curator
UniProt
UniProt protein ID
Q07955
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07955
determination method
IPI
retrieved
8 April 2019
stated in
A protein related to splicing factor U2AF35 that interacts with U2AF65 and SR proteins in splicing of pre-mRNA
GOA
curator
UniProt
UniProt protein ID
Q07955
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07955
determination method
IPI
retrieved
8 April 2019
stated in
NSrp70 is a novel nuclear speckle-related protein that modulates alternative pre-mRNA splicing in vivo
GOA
curator
UniProt
UniProt protein ID
Q07955
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07955
determination method
IPI
retrieved
8 April 2019
stated in
A novel transcriptional coactivator, p52, functionally interacts with the essential splicing factor ASF/SF2
GOA
curator
UniProt
UniProt protein ID
Q07955
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07955
determination method
IPI
retrieved
8 April 2019
stated in
The protein interaction landscape of the human CMGC kinase group
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07955
determination method
IPI
retrieved
8 April 2019
stated in
Spatial mapping of splicing factor complexes involved in exon and intron definition
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07955
determination method
IPI
retrieved
8 April 2019
stated in
CIR, a corepressor of CBF1, binds to PAP-1 and effects alternative splicing
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07955
determination method
IPI
retrieved
8 April 2019
stated in
The subcellular localization of SF2/ASF is regulated by direct interaction with SR protein kinases (SRPKs)
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07955
determination method
IPI
retrieved
8 April 2019
stated in
Hypophosphorylated ASF/SF2 binds TAP and is present in messenger ribonucleoproteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07955
determination method
IPI
retrieved
8 April 2019
stated in
The DEAD-box RNA helicase DDX3 associates with export messenger ribonucleoproteins as well as tip-associated protein and participates in translational control
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07955
determination method
IPI
retrieved
8 April 2019
stated in
RRP1B is a metastasis modifier that regulates the expression of alternative mRNA isoforms through interactions with SRSF1.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07955
determination method
IPI
retrieved
8 April 2019
stated in
Toward an understanding of the protein interaction network of the human liver
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07955
determination method
IPI
retrieved
8 April 2019
stated in
Treatment with IL-17 prolongs the half-life of chemokine CXCL1 mRNA via the adaptor TRAF5 and the splicing-regulatory factor SF2 (ASF)
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07955
determination method
IPI
retrieved
8 April 2019
stated in
Human p32, interacts with B subunit of the CCAAT-binding factor, CBF/NF-Y, and inhibits CBF-mediated transcription activation in vitro
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07955
determination method
IPI
retrieved
8 April 2019
stated in
RRP1B targets PP1 to mammalian cell nucleoli and is associated with Pre-60S ribosomal subunits
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07955
determination method
IPI
RNA binding
determination method
IDA
IEA
IPI
6 references
retrieved
26 September 2017
stated in
The Nuclear-Retained Noncoding RNA MALAT1 Regulates Alternative Splicing by Modulating SR Splicing Factor Phosphorylation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07955&geneProductId=UniProtKB:Q07955
determination method
IPI
retrieved
26 September 2017
stated in
GOA
curator
UniProt
UniProt protein ID
Q07955
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07955&geneProductId=UniProtKB:Q07955
determination method
IEA
retrieved
26 September 2017
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07955&geneProductId=UniProtKB:Q07955
determination method
IEA
retrieved
26 September 2017
stated in
Rapid and systematic analysis of the RNA recognition specificities of RNA-binding proteins
GOA
curator
UniProt
UniProt protein ID
Q07955
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07955&geneProductId=UniProtKB:Q07955
determination method
IDA
retrieved
26 September 2017
stated in
The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts
GOA
curator
UniProt
UniProt protein ID
Q07955
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07955&geneProductId=UniProtKB:Q07955
determination method
IDA
retrieved
26 September 2017
stated in
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins
GOA
curator
UniProt
UniProt protein ID
Q07955
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07955&geneProductId=UniProtKB:Q07955
determination method
IDA
RNA binding
determination method
HDA
IBA
IDA
IEA
IPI
7 references
retrieved
8 April 2019
stated in
The Nuclear-Retained Noncoding RNA MALAT1 Regulates Alternative Splicing by Modulating SR Splicing Factor Phosphorylation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07955
determination method
IPI
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q07955
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07955
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07955
determination method
IEA
retrieved
8 April 2019
stated in
Rapid and systematic analysis of the RNA recognition specificities of RNA-binding proteins
GOA
curator
UniProt
UniProt protein ID
Q07955
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07955
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07955
determination method
IBA
retrieved
8 April 2019
stated in
The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts
GOA
curator
UniProt
UniProt protein ID
Q07955
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07955
determination method
HDA
retrieved
8 April 2019
stated in
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins
GOA
curator
UniProt
UniProt protein ID
Q07955
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07955
determination method
HDA
cell component
biological process

Identifiers

 
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