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Lebercilin LCA5
mammalian protein found in Homo sapiens
epididymis secretory sperm binding protein
lebercilin
LCA5, lebercilin
LCA5
leber congenital amaurosis 5 protein
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q86VQ0
subclass of
protein
1 reference
stated in
UniProt
retrieved
1 December 2016
UniProt protein ID
Q86VQ0
part of
Lebercilin
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q86VQ0
Lebercilin domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q86VQ0
encoded by
LCA5
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q86VQ0
molecular function
protein binding
determination method
IPI
5 references
retrieved
8 April 2019
stated in
FAM161A, associated with retinitis pigmentosa, is a component of the cilia-basal body complex and interacts with proteins involved in ciliopathies
GOA
curator
UniProt
UniProt protein ID
Q86VQ0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VQ0
determination method
IPI
retrieved
8 April 2019
stated in
OFD1 is mutated in X-linked Joubert syndrome and interacts with LCA5-encoded lebercilin
GOA
curator
UniProt
UniProt protein ID
Q86VQ0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VQ0
determination method
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VQ0
determination method
IPI
retrieved
8 April 2019
stated in
An organelle-specific protein landscape identifies novel diseases and molecular mechanisms
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VQ0
determination method
IPI
retrieved
8 April 2019
stated in
A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VQ0
determination method
IPI
protein-containing complex binding
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Disruption of intraflagellar protein transport in photoreceptor cilia causes Leber congenital amaurosis in humans and mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VQ0
determination method
IDA
cell component
cytoplasm
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q86VQ0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VQ0
determination method
IEA
cell projection
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q86VQ0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VQ0
determination method
IEA
cilium
determination method
IDA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q86VQ0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VQ0
determination method
IEA
retrieved
8 April 2019
stated in
Disruption of intraflagellar protein transport in photoreceptor cilia causes Leber congenital amaurosis in humans and mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VQ0
determination method
IDA
cytoskeleton
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q86VQ0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VQ0
determination method
IEA
microtubule organizing center
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q86VQ0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VQ0
determination method
IEA
axoneme
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VQ0
determination method
IBA
photoreceptor connecting cilium
determination method
IDA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VQ0
determination method
IEA
retrieved
8 April 2019
stated in
Disruption of intraflagellar protein transport in photoreceptor cilia causes Leber congenital amaurosis in humans and mice
GOA
curator
UniProt
UniProt protein ID
Q86VQ0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VQ0
determination method
IDA
ciliary basal body
determination method
IEA
ISS
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q86VQ0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VQ0
determination method
ISS
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VQ0
determination method
IEA
biological process
protein transport
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q86VQ0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VQ0
determination method
IEA
intraciliary transport
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VQ0
determination method
IBA
photoreceptor cell maintenance
determination method
ISS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q86VQ0
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86VQ0
determination method
ISS
has part(s)
Lebercilin domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q86VQ0
Identifiers
RefSeq protein ID
NP_001116241
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
167691
NP_859065
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
167691
XP_005248722
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
167691
XP_011533806
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
167691
UniProt protein ID
Q86VQ0
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q86VQ0
Ensembl protein ID
ENSP00000358861
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000358861
ENSP00000376686
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000376686
ENSP00000474463
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000474463
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