(Q21172781)

English

Ubiquitin conjugating enzyme E2 V1

mammalian protein found in Homo sapiens

TMEM189-UBE2V1
UBE2V1
CROC-1
ubiquitin-conjugating enzyme E2 variant 1
DNA-binding protein
TRAF6-regulated IKK activator 1 beta Uev1A
TMEM189-UBE2V1 fusion protein
transmembrane protein 189-ubiquitin-conjugating enzyme E2 variant 1 read-through
TMEM189-UBE2V1 readthrough transcript

In more languages

default for all languages

No label defined

No description defined

Statements

1 reference

13 November 2019

UniProt protein ID

1 reference

1 December 2016

UniProt protein ID

Ubiquitin-conjugating enzyme/RWD-like

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q13404

Ubiquitin-conjugating enzyme E2 family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

1 reference

26 February 2020

UniProt protein ID

molecular function

protein binding

determination method

5 references

8 April 2019

Chaperoned ubiquitylation--crystal structures of the CHIP U box E3 ubiquitin ligase and a CHIP-Ubc13-Uev1a complex

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13404

determination method

8 April 2019

Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13404

determination method

8 April 2019

The MEKK1 PHD ubiquitinates TAB1 to activate MAPKs in response to cytokines

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13404

determination method

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13404

determination method

8 April 2019

Distinct regulation of Ubc13 functions by the two ubiquitin-conjugating enzyme variants Mms2 and Uev1A

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13404

determination method

ubiquitin protein ligase activity

determination method

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13404&geneProductId=UniProtKB:Q13404

determination method

ubiquitin protein ligase binding

determination method

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13404&geneProductId=UniProtKB:Q13404

determination method

ubiquitin conjugating enzyme activity

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13404

determination method

determination method

1 reference

8 April 2019

Distinct regulation of Ubc13 functions by the two ubiquitin-conjugating enzyme variants Mms2 and Uev1A

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13404

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13404

determination method

ubiquitin conjugating enzyme complex

determination method

1 reference

8 April 2019

Distinct regulation of Ubc13 functions by the two ubiquitin-conjugating enzyme variants Mms2 and Uev1A

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13404

determination method

UBC13-UEV1A complex

determination method

1 reference

8 April 2019

Chaperoned ubiquitylation--crystal structures of the CHIP U box E3 ubiquitin ligase and a CHIP-Ubc13-Uev1a complex

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13404

determination method

ubiquitin ligase complex

determination method

1 reference

8 April 2019

Chaperoned ubiquitylation--crystal structures of the CHIP U box E3 ubiquitin ligase and a CHIP-Ubc13-Uev1a complex

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13404

determination method

extracellular exosome

determination method

3 references

17 October 2017

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13404&geneProductId=UniProtKB:Q13404

determination method

17 October 2017

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13404&geneProductId=UniProtKB:Q13404

determination method

17 October 2017

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13404&geneProductId=UniProtKB:Q13404

determination method

determination method

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13404

determination method

determination method

3 references

8 April 2019

CROC-1 encodes a protein which mediates transcriptional activation of the human FOS promoter

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13404

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13404

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13404

determination method

protein-containing complex

determination method

1 reference

8 April 2019

ZNRF2 is released from membranes by growth factors and, together with ZNRF1, regulates the Na+/K+ATPase

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13404

determination method

biological process

protein polyubiquitination

determination method

1 reference

8 April 2019

Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13404

determination method

Fc-epsilon receptor signaling pathway

determination method

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13404&geneProductId=UniProtKB:Q13404

determination method

protein K63-linked ubiquitination

determination method

nucleotide-binding oligomerization domain containing signaling pathway

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13404

determination method

positive regulation of transcription, DNA-templated

determination method

1 reference

8 April 2019

CROC-1 encodes a protein which mediates transcriptional activation of the human FOS promoter

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13404

determination method

stimulatory C-type lectin receptor signaling pathway

determination method

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13404&geneProductId=UniProtKB:Q13404

determination method

regulation of DNA repair

determination method

1 reference

8 April 2019

Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13404

determination method

regulation of transcription, DNA-templated

determination method

1 reference

8 April 2019

CROC-1 encodes a protein which mediates transcriptional activation of the human FOS promoter

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13404

determination method

T cell receptor signaling pathway

determination method

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13404&geneProductId=UniProtKB:Q13404

determination method

cell differentiation

determination method

1 reference

8 April 2019

Role of UEV-1, an inactive variant of the E2 ubiquitin-conjugating enzymes, in in vitro differentiation and cell cycle behavior of HT-29-M6 intestinal mucosecretory cells.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13404

determination method

postreplication repair

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13404

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13404

determination method

positive regulation of I-kappaB kinase/NF-kappaB signaling

determination method

1 reference

8 April 2019

Distinct regulation of Ubc13 functions by the two ubiquitin-conjugating enzyme variants Mms2 and Uev1A

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13404

determination method

interleukin-1-mediated signaling pathway

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13404

determination method

protein K63-linked ubiquitination

determination method

3 references

8 April 2019

Chaperoned ubiquitylation--crystal structures of the CHIP U box E3 ubiquitin ligase and a CHIP-Ubc13-Uev1a complex

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13404

determination method

8 April 2019

TRIM5 is an innate immune sensor for the retrovirus capsid lattice

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13404

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13404

determination method

Ubiquitin-conjugating enzyme E2

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q13404

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 June 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000407770

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000407770

ENSP00000360739

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000360739

ENSP00000395264

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000395264

ENSP00000360742

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000360742

ENSP00000340305

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000340305

ENSP00000484828

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000484828

ENSP00000485599

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000485599

ENSP00000450635

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000450635

ENSP00000421351

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000421351

ENSP00000360720

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000360720

ENSP00000344166

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000344166

PDB structure ID

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

1 reference

UniProt protein ID

30 June 2016

language of work or name

Sitelinks

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Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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