Wikidata

(Q21172844)

English

THAP domain containing 1

mammalian protein found in Homo sapiens

  • THAP domain containing, apoptosis associated protein 1
  • THAP domain-containing protein 1
  • nuclear proapoptotic factor
  • THAP domain protein 1
  • 4833431A01Rik
  • THAP1
In more languages

Statements

molecular function
sequence-specific DNA binding
determination method
IDA
IMP
5 references
retrieved
8 April 2019
stated in
Mutations in the THAP1 gene are responsible for DYT6 primary torsion dystonia
GOA
curator
UniProt
UniProt protein ID
Q9NVV9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NVV9
determination method
IMP
retrieved
8 April 2019
stated in
The THAP domain of THAP1 is a large C2CH module with zinc-dependent sequence-specific DNA-binding activity
GOA
curator
UniProt
UniProt protein ID
Q9NVV9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NVV9
determination method
IDA
retrieved
8 April 2019
stated in
Structure-function analysis of the THAP zinc finger of THAP1, a large C2CH DNA-binding module linked to Rb/E2F pathways
GOA
curator
UniProt
UniProt protein ID
Q9NVV9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NVV9
determination method
IDA
retrieved
8 April 2019
stated in
THAP proteins target specific DNA sites through bipartite recognition of adjacent major and minor grooves
GOA
curator
UniProt
UniProt protein ID
Q9NVV9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NVV9
determination method
IDA
retrieved
8 April 2019
stated in
The THAP-zinc finger protein THAP1 regulates endothelial cell proliferation through modulation of pRB/E2F cell-cycle target genes
GOA
curator
UniProt
UniProt protein ID
Q9NVV9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NVV9
determination method
IDA
protein binding
determination method
IPI
6 references
retrieved
8 April 2019
stated in
The THAP-zinc finger protein THAP1 associates with coactivator HCF-1 and O-GlcNAc transferase: a link between DYT6 and DYT3 dystonias
GOA
curator
UniProt
UniProt protein ID
Q9NVV9
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NVV9
determination method
IPI
retrieved
8 April 2019
stated in
Next-generation sequencing to generate interactome datasets
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NVV9
determination method
IPI
retrieved
8 April 2019
stated in
Towards a proteome-scale map of the human protein–protein interaction network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NVV9
determination method
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NVV9
determination method
IPI
retrieved
8 April 2019
stated in
Widespread macromolecular interaction perturbations in human genetic disorders
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NVV9
determination method
IPI
retrieved
8 April 2019
stated in
Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NVV9
determination method
IPI
cell component
biological process

Identifiers

 
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