(Q21173483)

Myocardin

1 reference

SAP domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

RPEL repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

transcription coactivator activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IZQ8&geneProductId=UniProtKB:Q8IZQ8

1 reference

24 April 2018

IBA

R-SMAD binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

DNA-binding transcription activator activity, RNA polymerase II-specific

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

8 April 2019

Leiomodin 1, a new serum response factor-dependent target gene expressed preferentially in differentiated smooth muscle cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

8 April 2019

miR-145 and miR-143 regulate smooth muscle cell fate and plasticity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

DNA-binding transcription activator activity, RNA polymerase II-specific

1 reference

10 September 2018

Leiomodin 1, a new serum response factor-dependent target gene expressed preferentially in differentiated smooth muscle cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IZQ8&geneProductId=UniProtKB:Q8IZQ8

transcription factor binding

1 reference

8 April 2019

Phenotypic modulation of smooth muscle cells through interaction of Foxo4 and myocardin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

histone deacetylase binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

core promoter sequence-specific DNA binding

1 reference

24 April 2018

Myocardin-dependent activation of the CArG box-rich smooth muscle gamma-actin gene: preferential utilization of a single CArG element through functional association with the NKX3.1 homeodomain protein

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IZQ8&geneProductId=UniProtKB:Q8IZQ8

protein binding

4 references

8 April 2019

Myocardin-dependent activation of the CArG box-rich smooth muscle gamma-actin gene: preferential utilization of a single CArG element through functional association with the NKX3.1 homeodomain protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

8 April 2019

Potentiation of serum response factor activity by a family of myocardin-related transcription factors

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

8 April 2019

Megakaryoblastic leukemia factor-1 transduces cytoskeletal signals and induces smooth muscle cell differentiation from undifferentiated embryonic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

histone acetyltransferase binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

cis-regulatory region sequence-specific DNA binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

RNA polymerase II cis-regulatory region sequence-specific DNA binding

1 reference

8 April 2019

Myocardin-dependent activation of the CArG box-rich smooth muscle gamma-actin gene: preferential utilization of a single CArG element through functional association with the NKX3.1 homeodomain protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

cell component

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

8 April 2019

Megakaryoblastic leukemia factor-1 transduces cytoskeletal signals and induces smooth muscle cell differentiation from undifferentiated embryonic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

cellular component maintenance

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

positive regulation of transforming growth factor beta receptor signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

response to hypoxia

IEP

1 reference

8 April 2019

SRF and myocardin regulate LRP-mediated amyloid-beta clearance in brain vascular cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

regulation of transcription, DNA-templated

IEP

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IZQ8&geneProductId=UniProtKB:Q8IZQ8

1 reference

5 June 2018

negative regulation of cyclin-dependent protein serine/threonine kinase activity

1 reference

8 April 2019

Myocardin is sufficient for a smooth muscle-like contractile phenotype

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

urinary bladder development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

regulation of transcription by RNA polymerase II

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

vascular associated smooth muscle cell differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

cardiac ventricle development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

regulation of cell growth by extracellular stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

negative regulation of transcription by RNA polymerase II

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IZQ8&geneProductId=UniProtKB:Q8IZQ8

1 reference

5 June 2018

regulation of phenotypic switching

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

vasculogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

positive regulation of transcription, DNA-templated

uterus development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

negative regulation of skeletal muscle cell differentiation

1 reference

8 April 2019

Myocardin is sufficient for a smooth muscle-like contractile phenotype

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

negative regulation of cardiac muscle cell apoptotic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

heart development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

muscle cell differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

negative regulation of amyloid-beta clearance

IMP

1 reference

8 April 2019

SRF and myocardin regulate LRP-mediated amyloid-beta clearance in brain vascular cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

positive regulation of smooth muscle cell differentiation

IMP

1 reference

8 April 2019

Myocardin is sufficient for a smooth muscle-like contractile phenotype

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

regulation of myoblast differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

positive regulation of cell population proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

negative regulation of myotube differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation

1 reference

8 April 2019

Activation of cardiac and smooth muscle-specific genes in primary human cells after forced expression of human myocardin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

positive regulation of cardiac vascular smooth muscle cell differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

ventricular cardiac muscle cell differentiation

ISS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

positive regulation of DNA binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

lung alveolus development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

digestive tract development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

positive regulation of smooth muscle contraction

1 reference

8 April 2019

Serum response factor and myocardin mediate arterial hypercontractility and cerebral blood flow dysregulation in Alzheimer's phenotype

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

cardiocyte differentiation

NAS

1 reference

8 April 2019

Myocardin is a critical serum response factor cofactor in the transcriptional program regulating smooth muscle cell differentiation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

ductus arteriosus closure

NAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

positive regulation of transcription by RNA polymerase II

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

8 April 2019

miR-145 and miR-143 regulate smooth muscle cell fate and plasticity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

8 April 2019

Megakaryoblastic leukemia factor-1 transduces cytoskeletal signals and induces smooth muscle cell differentiation from undifferentiated embryonic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

8 April 2019

Serum response factor and myocardin mediate arterial hypercontractility and cerebral blood flow dysregulation in Alzheimer's phenotype

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

negative regulation of cell population proliferation

1 reference

8 April 2019

Myocardin is sufficient for a smooth muscle-like contractile phenotype

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

regulation of smooth muscle cell differentiation

TAS

1 reference

8 April 2019

Serum response factor and myocardin mediate arterial hypercontractility and cerebral blood flow dysregulation in Alzheimer's phenotype

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

transcription by RNA polymerase II

TAS

1 reference

5 June 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IZQ8&geneProductId=UniProtKB:Q8IZQ8

positive regulation of gene expression

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

negative regulation of vascular associated smooth muscle cell proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

negative regulation of vascular associated smooth muscle cell migration

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

negative regulation of platelet-derived growth factor receptor-beta signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

positive regulation of DNA-binding transcription factor activity

1 reference

8 April 2019

SRF and myocardin regulate LRP-mediated amyloid-beta clearance in brain vascular cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

smooth muscle cell differentiation

Megakaryoblastic leukemia factor-1 transduces cytoskeletal signals and induces smooth muscle cell differentiation from undifferentiated embryonic stem cells

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

cardiac muscle cell differentiation

IBA

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IZQ8

1 reference

RPEL repeat

1 reference