(Q21173746)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q01726

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

GPCR, rhodopsin-like, 7TM, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

G protein-coupled peptide receptor activity

1 reference

8 April 2019

Melanocortin-1 receptor signaling markedly induces the expression of the NR4A nuclear receptor subgroup in melanocytic cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01726

signal transducer activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01726&geneProductId=UniProtKB:Q01726

1 reference

1 January 2018

melanocyte-stimulating hormone receptor activity

protein binding

3 references

8 April 2019

MRAP and MRAP2 are bidirectional regulators of the melanocortin receptor family

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01726

8 April 2019

MRAP and MRAP2 are bidirectional regulators of the melanocortin receptor family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01726

8 April 2019

Novel binding motif of ACTH analogues at the melanocortin receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01726

melanocortin receptor activity

ubiquitin protein ligase binding

3 references

1 reference

8 April 2019

Mahogunin ring finger-1 (MGRN1) E3 ubiquitin ligase inhibits signaling from melanocortin receptor by competition with Galphas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01726

cell component

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01726

1 reference

8 April 2019

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01726

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01726

8 April 2019

8 April 2019

Aberrant trafficking of human melanocortin 1 receptor variants associated with red hair and skin cancer: Steady-state retention of mutant forms in the proximal golgi

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01726

integral component of plasma membrane

IDA

1 reference

8 April 2019

Human pigmentation phenotype: a point mutation generates nonfunctional MSH receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01726

intracellular anatomical structure

1 reference

10 September 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01726&geneProductId=UniProtKB:Q01726

G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

biological process

1 reference

8 April 2019

Human pigmentation phenotype: a point mutation generates nonfunctional MSH receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01726

multicellular organism development

1 reference

8 April 2019

Variants of the melanocyte-stimulating hormone receptor gene are associated with red hair and fair skin in humans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01726

UV protection

1 reference

8 April 2019

Variants of the melanocyte-stimulating hormone receptor gene are associated with red hair and fair skin in humans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01726

negative regulation of tumor necrosis factor production

IMP

1 reference

8 April 2019

alpha-MSH and its receptors in regulation of tumor necrosis factor-alpha production by human monocyte/macrophages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01726

UV-damage excision repair

IMP

IDA

1 reference

8 April 2019

Melanocortin-1 receptor signaling markedly induces the expression of the NR4A nuclear receptor subgroup in melanocytic cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01726

IDA

signal transduction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01726

1 reference

8 April 2019

positive regulation of protein kinase A signaling

1 reference

16 July 2018

Melanocortin-1 receptor signaling markedly induces the expression of the NR4A nuclear receptor subgroup in melanocytic cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01726&geneProductId=UniProtKB:Q01726

intracellular signal transduction

1 reference

16 July 2018

Melanocortin-1 receptor signaling markedly induces the expression of the NR4A nuclear receptor subgroup in melanocytic cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01726&geneProductId=UniProtKB:Q01726

pigmentation

1 reference

16 July 2018

Melanocortin-1 receptor signaling markedly induces the expression of the NR4A nuclear receptor subgroup in melanocytic cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01726&geneProductId=UniProtKB:Q01726

positive regulation of transcription by RNA polymerase II

1 reference

16 July 2018

Melanocortin-1 receptor signaling markedly induces the expression of the NR4A nuclear receptor subgroup in melanocytic cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01726&geneProductId=UniProtKB:Q01726

positive regulation of protein kinase B signaling

1 reference

16 July 2018

Melanocortin-1 receptor signaling markedly induces the expression of the NR4A nuclear receptor subgroup in melanocytic cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01726&geneProductId=UniProtKB:Q01726

positive regulation of protein kinase C signaling

1 reference

16 July 2018

Melanocortin-1 receptor signaling markedly induces the expression of the NR4A nuclear receptor subgroup in melanocytic cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01726&geneProductId=UniProtKB:Q01726

G protein-coupled receptor signaling pathway

sensory perception of pain

Ensembl genome database project

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01726

melanin biosynthetic process

Ensembl genome database project

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01726

physically interacts with

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

1324

language of work or name

17 August 2016

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

1323

language of work or name

English

GPCR, rhodopsin-like, 7TM

17 August 2016

has part(s)

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q01726

Identifiers

MeSH descriptor ID

D044102

subject named as

Receptor, Melanocortin, Type 1

0 references

MeSH tree code

D12.776.543.750.695.430.500

0 references

D12.776.543.750.720.600.285.500.500

0 references

D12.776.543.750.750.555.285.500.500

0 references

D12.776.543.750.750.660.285.500.500

0 references

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

0 references

Microsoft Academic ID

0 references

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

UMLS CUI

C0753910

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

UMLS 2023