(Q21173833)

English

Spartin

mammalian protein found in Homo sapiens

spastic paraplegia 20 (Troyer syndrome)
trans-activated by hepatitis C virus core protein 1
spartin
SPART
Spastic paraplegia 20 protein
SPG20

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Statements

1 reference

13 November 2019

1 reference

1 December 2016

MIT domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q8N0X7

MIT domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Senescence/spartin-associated domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

SPG20 protein spartin is recruited to midbodies by ESCRT-III protein Ist1 and participates in cytokinesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0X7

determination method

IPI

ubiquitin protein ligase binding

1 reference

8 April 2019

Endogenous spartin (SPG20) is recruited to endosomes and lipid droplets and interacts with the ubiquitin E3 ligases AIP4 and AIP5

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0X7

determination method

IPI

cell component

mitochondrial outer membrane

1 reference

8 April 2019

SPG20 protein spartin associates with cardiolipin via its plant-related senescence domain and regulates mitochondrial Ca2+ homeostasis

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0X7

1 reference

8 April 2019

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0X7

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N0X7&geneProductId=UniProtKB:Q8N0X7

1 reference

8 April 2019

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0X7

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0X7

1 reference

16 July 2018

SPG20 protein spartin is recruited to midbodies by ESCRT-III protein Ist1 and participates in cytokinesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N0X7&geneProductId=UniProtKB:Q8N0X7

determination method

IMP

regulation of mitochondrial membrane potential

1 reference

8 April 2019

SPG20 protein spartin associates with cardiolipin via its plant-related senescence domain and regulates mitochondrial Ca2+ homeostasis

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0X7

determination method

IMP

negative regulation of collateral sprouting in absence of injury

1 reference

8 April 2019

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0X7

determination method

IEA

adipose tissue development

1 reference

8 April 2019

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0X7

determination method

IEA

neuromuscular process

1 reference

8 April 2019

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0X7

1 reference

8 April 2019

SPG20 protein spartin is recruited to midbodies by ESCRT-III protein Ist1 and participates in cytokinesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0X7

determination method

IMP

lipid droplet organization

1 reference

8 April 2019

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N0X7

determination method

IEA

negative regulation of BMP signaling pathway

1 reference

16 July 2018

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N0X7&geneProductId=UniProtKB:Q8N0X7

1 reference

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q8N0X7

Senescence/spartin-associated

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q8N0X7

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

30 June 2016

language of work or name

1 reference

30 June 2016

language of work or name

English

(Q21173833)

Spartin

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Identifiers

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