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Transcription factor EB
mammalian protein found in Homo sapiens
TFEB
bHLHe35
transcription factor EB
T-cell transcription factor EB
class E basic helix-loop-helix protein 35
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P19484
subclass of
protein
1 reference
stated in
UniProt
retrieved
1 December 2016
UniProt protein ID
P19484
part of
Transcription factor EB
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P19484
Helix-loop-helix DNA-binding domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P19484
MiT/TFE transcription factors, C-terminal domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Myc-type, basic helix-loop-helix (bHLH) domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
MiT/TFE transcription factors, N-terminal domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P19484
encoded by
TFEB
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P19484
molecular function
DNA binding
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P19484
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19484
determination method
IEA
protein dimerization activity
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19484
determination method
IEA
DNA-binding transcription factor activity
determination method
IDA
NAS
2 references
retrieved
9 May 2019
stated in
A helix-loop-helix protein related to the immunoglobulin E box-binding proteins
GOA
curator
UniProt
UniProt protein ID
P19484
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19484
determination method
NAS
retrieved
9 May 2019
stated in
A gene network regulating lysosomal biogenesis and function
GOA
curator
UniProt
UniProt protein ID
P19484
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19484
determination method
IDA
DNA-binding transcription factor activity, RNA polymerase II-specific
determination method
ISA
ISM
NAS
3 references
retrieved
9 May 2019
stated in
A census of human transcription factors: function, expression and evolution
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19484
determination method
NAS
retrieved
9 May 2019
stated in
A census of human transcription factors: function, expression and evolution
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19484
determination method
ISM
retrieved
9 May 2019
stated in
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19484
determination method
ISA
cell component
cytoplasm
determination method
IEA
IDA
2 references
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P19484
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19484
determination method
IEA
retrieved
9 May 2019
stated in
A gene network regulating lysosomal biogenesis and function
GOA
curator
UniProt
UniProt protein ID
P19484
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19484
determination method
IDA
nucleus
determination method
IEA
IDA
NAS
3 references
retrieved
9 May 2019
stated in
A helix-loop-helix protein related to the immunoglobulin E box-binding proteins
GOA
curator
UniProt
UniProt protein ID
P19484
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19484
determination method
NAS
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P19484
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19484
determination method
IEA
retrieved
9 May 2019
stated in
A gene network regulating lysosomal biogenesis and function
GOA
curator
UniProt
UniProt protein ID
P19484
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19484
determination method
IDA
biological process
autophagy
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P19484
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19484
determination method
IEA
positive regulation of transcription, DNA-templated
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19484
determination method
IEA
embryonic placenta development
determination method
ISS
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P19484
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19484
determination method
ISS
lysosome organization
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
ZKSCAN3 is a master transcriptional repressor of autophagy
GOA
curator
UniProt
UniProt protein ID
P19484
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19484
determination method
IMP
adaptive immune response
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P19484
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19484
determination method
IEA
transcription, DNA-templated
determination method
IEA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P19484
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19484&geneProductId=UniProtKB:P19484
determination method
IEA
positive regulation of autophagy
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
ZKSCAN3 is a master transcriptional repressor of autophagy
GOA
curator
UniProt
UniProt protein ID
P19484
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19484
determination method
IMP
positive regulation of transcription by RNA polymerase II
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
A gene network regulating lysosomal biogenesis and function
GOA
curator
UniProt
UniProt protein ID
P19484
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19484
determination method
IDA
immune system process
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P19484
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19484
determination method
IEA
humoral immune response
determination method
IEA
ISS
2 references
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P19484
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19484
determination method
ISS
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19484
determination method
IEA
regulation of transcription, DNA-templated
determination method
IEA
NAS
2 references
retrieved
9 May 2019
stated in
A helix-loop-helix protein related to the immunoglobulin E box-binding proteins
GOA
curator
UniProt
UniProt protein ID
P19484
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19484
determination method
NAS
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19484
determination method
IEA
lysosome localization
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
TFEB regulates lysosomal positioning by modulating TMEM55B expression and JIP4 recruitment to lysosomes.
GOA
curator
UniProt
UniProt protein ID
P19484
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19484
determination method
IMP
positive regulation of transcription, DNA-templated
determination method
IDA
IEA
2 references
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19484
determination method
IEA
retrieved
9 May 2019
stated in
TFEB regulates lysosomal positioning by modulating TMEM55B expression and JIP4 recruitment to lysosomes.
GOA
curator
UniProt
UniProt protein ID
P19484
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19484
determination method
IDA
has part(s)
MiT/TFE transcription factors, N-terminal
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P19484
Myc-type, basic helix-loop-helix (bHLH) domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P19484
MiT/TFE transcription factors, C-terminal
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P19484
Identifiers
RefSeq protein ID
NP_001161299
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
7942
NP_001258872
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
7942
NP_001258873
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
7942
NP_001258874
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
7942
NP_009093
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
7942
XP_005249468
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
7942
XP_005249469
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
7942
XP_006715275
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
7942
XP_011513217
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
7942
XP_011513218
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
7942
UniProt protein ID
P19484
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P19484
Ensembl protein ID
ENSP00000230323
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000230323
ENSP00000362124
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000362124
ENSP00000384203
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000384203
ENSP00000412551
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000412551
ENSP00000343948
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000343948
ENSP00000351742
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000351742
ENSP00000377824
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000377824
ENSP00000383998
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000383998
ENSP00000393874
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000393874
ENSP00000395208
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000395208
ENSP00000396168
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000396168
ENSP00000400276
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000400276
ENSP00000406491
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000406491
ENSP00000410391
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000410391
ENSP00000415035
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000415035
ENSP00000415946
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000415946
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