(Q21195877)

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Chloroquine treatment of ARPE-19 cells leads to lysosome dilation and intracellular lipid accumulation: possible implications of lysosomal dysfunction in macular degeneration

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scholarly article

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Chloroquine treatment of ARPE-19 cells leads to lysosome dilation and intracellular lipid accumulation: possible implications of lysosomal dysfunction in macular degeneration (English)

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macular degeneration

1 reference

based on heuristic

inferred from title

author name string

Patrick M Chen

1

author given names

Patrick M

author last names

Chen

1 reference

Dimensions Publication ID

18 August 2022

Zoë J Gombart

2

author given names

Zoë J

author last names

Gombart

1 reference

Dimensions Publication ID

18 August 2022

Jeff W Chen

3

author given names

Jeff W

author last names

Chen

1 reference

Dimensions Publication ID

18 August 2022

language of work or name

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publication date

2011

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Cell & Bioscience

1 reference

1

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1

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10

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describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3125200/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

https://scigraph.springernature.com/pub.10.1186/2045-3701-1-10

0 references

Roles of LAMP-1 and LAMP-2 in lysosome biogenesis and autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125200

19 March 2017

Affordable image analysis using NIH Image/ImageJ

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125200

19 March 2017

Participation of the retinal pigment epithelium in the rod outer segment renewal process

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125200

19 March 2017

Accumulation of autophagic vacuoles and cardiomyopathy in LAMP-2-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125200

28 May 2017

Lipid peroxidation products reduce lysosomal protease activities in human retinal pigment epithelial cells via two different mechanisms of action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125200

12 September 2017

Lack of Niemann-Pick type C1 induces age-related degeneration in the mouse retina

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125200

12 September 2017

Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125200

12 September 2017

Heat shock proteins as gatekeepers of proteolytic pathways-Implications for age-related macular degeneration (AMD).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125200

12 September 2017

The role of the photoreceptor ABC transporter ABCA4 in lipid transport and Stargardt macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125200

12 September 2017

Restoration of lysosomal pH in RPE cells from cultured human and ABCA4(-/-) mice: pharmacologic approaches and functional recovery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125200

12 September 2017

Overview of progress in the epidemiology of age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125200

12 September 2017

Lysosomes: fusion and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125200

12 September 2017

The lysosomal-mitochondrial axis theory of postmitotic aging and cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125200

12 September 2017

The retinal pigment epithelium in visual function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125200

12 September 2017

Age-Related Macular Degeneration: Etiology, Pathogenesis, and Therapeutic Strategies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125200

12 September 2017

Progressive age-related changes similar to age-related macular degeneration in a transgenic mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125200

12 September 2017

Age-related macular degeneration: epidemiology and optimal treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125200

12 September 2017

The lipofuscin component A2E selectively inhibits phagolysosomal degradation of photoreceptor phospholipid by the retinal pigment epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125200

12 September 2017

Effect of weak bases on the intralysosomal pH in mouse peritoneal macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125200

12 September 2017

Dysfunction of the retinal pigment epithelium with age: increased iron decreases phagocytosis and lysosomal activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125200

27 September 2017

Prematurely senescent ARPE-19 cells display features of age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125200

27 September 2017

Oxidative stress in ARPE-19 cultures: do melanosomes confer cytoprotection?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125200

27 September 2017

Asparagine-linked oligosaccharides protect Lamp-1 and Lamp-2 from intracellular proteolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125200

27 September 2017

Chloroquine retinopathy in the rhesus monkey

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125200

27 September 2017

Induction of lysosomal dilatation, arrested autophagy, and cell death by chloroquine in cultured ARPE-19 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125200

30 May 2018

LAMP proteins are required for fusion of lysosomes with phagosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125200

30 May 2018

Chloroquine causes lysosomal dysfunction in neural retina and RPE: implications for retinopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125200

30 May 2018

Different effects of chloroquine and hydroxychloroquine on lysosomal function in cultured retinal pigment epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125200

30 May 2018

Distribution of cathepsin D in human eyes with or without age-related maculopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125200

30 May 2018

Lysosomal enzyme cytochemistry of human RPE, Bruch's membrane and drusen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125200

30 May 2018

The blood-retinal barrier in chloroquine retinopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125200

30 May 2018

Age-Related Macular Degeneration

1 reference

https://api.crossref.org/works/10.1186%2F2045-3701-1-10

21 January 2018

Autophagy, exosomes and drusen formation in age-related macular degeneration

1 reference

https://api.crossref.org/works/10.1186%2F2045-3701-1-10

21 January 2018

Cystatin C in macular and neuronal degenerations: implications for mechanism(s) of age-related macular degeneration

1 reference

https://api.crossref.org/works/10.1186%2F2045-3701-1-10

21 January 2018

Nuclear gene expression changes due to mitochondrial dysfunction in ARPE-19 cells: implications for age-related macular degeneration

1 reference

https://api.crossref.org/works/10.1186%2F2045-3701-1-10

21 January 2018

Accumulation of oxidized lipid-protein complexes alters phagosome maturation in retinal pigment epithelium

1 reference

https://api.crossref.org/works/10.1186%2F2045-3701-1-10

21 January 2018

Inhibition of the ATP-driven proton pump in RPE lysosomes by the major lipofuscin fluorophore A2-E may contribute to the pathogenesis of age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125200

29 November 2018

Lamp-1 is upregulated in human glioblastoma cell lines induced to undergo apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125200

29 November 2018

Age-related macular degeneration: review of pathogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125200

29 November 2018

Age-related changes of glycosidases in human retinal pigment epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125200

29 November 2018

Postfixation detergent treatment for immunofluorescence suppresses localization of some integral membrane proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/21711726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fourteen-year incidence of age-related maculopathy and cause-specific prevalence of visual impairment and blindness in a Caucasian population: the Copenhagen City Eye Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/21711726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of Lipid Peroxidation-Related Protein Modifications on RPE Lysosomal Functions and POS Phagocytosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21711726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LAMP-2: a control step for phagosome and autophagosome maturation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21711726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Shedding of discs from rod outer segments in the rhesus monkey

1 reference

https://pubmed.ncbi.nlm.nih.gov/21711726

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/2045-3701-1-10

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release_kvnbxxkmifgjxcr654g5nznkle

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