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(Q21421153)
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Defensin, alpha 1
mammalian protein found in Mus musculus
defensin-related cryptdin peptide
defensin-1
alpha-defensin 1
defensin related cryptdin peptide 1
Defa1
cryptdin-1
In more languages
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P11477
subclass of
protein
1 reference
stated in
UniProt
retrieved
19 January 2017
UniProt protein ID
P11477
part of
Alpha-defensin propeptide
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P11477
Beta/alpha defensin, protein family
1 reference
based on heuristic
inferred from protein domain or family
Defensin propeptide family
1 reference
based on heuristic
inferred from protein domain or family
alpha defensin
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
house mouse
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P11477
encoded by
Defa1
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P11477
cell component
extracellular region
determination method
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P11477
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11477
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11477
determination method
IEA
extracellular space
determination method
IDA
IEA
2 references
retrieved
27 March 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11477&geneProductId=UniProtKB:P11477
determination method
IEA
retrieved
27 March 2018
stated in
Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11477&geneProductId=UniProtKB:P11477
determination method
IDA
extracellular space
determination method
IBA
IDA
IEA
3 references
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11477
determination method
IEA
retrieved
14 February 2019
stated in
Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11477
determination method
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11477
determination method
IBA
biological process
defense response
determination method
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P11477
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11477
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11477
determination method
IEA
cellular response to lipopolysaccharide
determination method
IGI
1 reference
retrieved
27 March 2018
stated in
Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11477&geneProductId=UniProtKB:P11477
determination method
IGI
defense response to bacterium
determination method
IDA
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P11477
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11477
determination method
IEA
retrieved
14 February 2019
stated in
Mouse Paneth cell defensins: primary structures and antibacterial activities of numerous cryptdin isoforms
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11477
determination method
IDA
defense response to Gram-negative bacterium
determination method
IGI
1 reference
retrieved
27 March 2018
stated in
Elevated sensitivity to diet-induced obesity and insulin resistance in mice lacking 4E-BP1 and 4E-BP2
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11477&geneProductId=UniProtKB:P11477
determination method
IGI
defense response to Gram-positive bacterium
determination method
IGI
1 reference
retrieved
27 March 2018
stated in
Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P11477&geneProductId=UniProtKB:P11477
determination method
IGI
innate immune response in mucosa
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11477
determination method
IBA
antibacterial humoral response
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11477
determination method
IBA
defense response to Gram-negative bacterium
determination method
IBA
IGI
2 references
retrieved
14 February 2019
stated in
Elevated sensitivity to diet-induced obesity and insulin resistance in mice lacking 4E-BP1 and 4E-BP2
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11477
determination method
IGI
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11477
determination method
IBA
defense response to Gram-positive bacterium
determination method
IBA
IGI
2 references
retrieved
14 February 2019
stated in
Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11477
determination method
IGI
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11477
determination method
IBA
membrane disruption in other organism
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11477
determination method
IBA
antimicrobial humoral immune response mediated by antimicrobial peptide
determination method
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11477
determination method
IBA
cellular response to lipopolysaccharide
determination method
IBA
IGI
2 references
retrieved
14 February 2019
stated in
Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11477
determination method
IGI
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11477
determination method
IBA
has part(s)
Alpha defensin
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P11477
Defensin propeptide
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P11477
Beta/alpha defensin
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P11477
Identifiers
RefSeq protein ID
NP_034161
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
13216
UniProt protein ID
P11477
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P11477
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