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NLR family, apoptosis inhibitory protein 5
mammalian protein found in Mus musculus
Legionella, susceptiblility 1
baculoviral IAP repeat-containing 1e
neuronal apoptosis inhibitory protein, related sequence 3
Naip5
baculoviral IAP repeat-containing protein 1e
neuronal apoptosis inhibitory protein 5
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9R016
subclass of
protein
1 reference
stated in
UniProt
retrieved
19 January 2017
UniProt protein ID
Q9R016
part of
Leucine-rich repeat domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9R016
Baculoviral IAP repeat-containing protein 1
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9R016
P-loop containing nucleoside triphosphate hydrolase
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9R016
NACHT nucleoside triphosphatase family
1 reference
based on heuristic
inferred from protein domain or family
BIR repeat domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
house mouse
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9R016
encoded by
Naip5
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9R016
molecular function
ubiquitin-protein transferase activity
determination method
IBA
1 reference
retrieved
24 April 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9R016&geneProductId=UniProtKB:Q9R016
determination method
IBA
nucleotide binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9R016
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R016
determination method
IEA
metal ion binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9R016
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R016
determination method
IEA
cysteine-type endopeptidase inhibitor activity involved in apoptotic process
determination method
IBA
IEA
2 references
retrieved
24 April 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9R016&geneProductId=UniProtKB:Q9R016
determination method
IEA
retrieved
24 April 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9R016&geneProductId=UniProtKB:Q9R016
determination method
IBA
protein binding
determination method
IPI
5 references
retrieved
8 April 2019
stated in
Cryoelectron Tomography of the NAIP5/NLRC4 Inflammasome: Implications for NLR Activation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R016
determination method
IPI
retrieved
8 April 2019
stated in
Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R016
determination method
IPI
retrieved
8 April 2019
stated in
Crystal structure of NLRC4 reveals its autoinhibition mechanism
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R016
determination method
IPI
retrieved
8 April 2019
stated in
The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R016
determination method
IPI
retrieved
8 April 2019
stated in
Structural and biochemical basis for induced self-propagation of NLRC4.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R016
determination method
IPI
ATP binding
determination method
IDA
IEA
ISS
3 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9R016
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R016
determination method
ISS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9R016
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R016
determination method
IEA
retrieved
8 April 2019
stated in
Structural basis for specific flagellin recognition by the NLR protein NAIP5.
GOA
curator
UniProt
UniProt protein ID
Q9R016
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R016
determination method
IDA
cysteine-type endopeptidase inhibitor activity involved in apoptotic process
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R016
determination method
IEA
cell component
IPAF inflammasome complex
determination method
IDA
2 references
retrieved
8 April 2019
stated in
Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity
GOA
curator
UniProt
UniProt protein ID
Q9R016
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R016
determination method
IDA
retrieved
8 April 2019
stated in
Structural basis for specific flagellin recognition by the NLR protein NAIP5.
GOA
curator
UniProt
UniProt protein ID
Q9R016
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R016
determination method
IDA
nucleus
determination method
IBA
1 reference
retrieved
24 April 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9R016&geneProductId=UniProtKB:Q9R016
determination method
IBA
cytoplasm
determination method
ISO
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R016
determination method
ISO
neuron projection
determination method
ISO
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R016
determination method
ISO
neuronal cell body
determination method
ISO
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R016
determination method
ISO
perikaryon
determination method
ISO
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R016
determination method
ISO
biological process
innate immune response
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9R016
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R016
determination method
IEA
inflammatory response
determination method
IEA
IMP
2 references
retrieved
8 April 2019
stated in
Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity
GOA
curator
UniProt
UniProt protein ID
Q9R016
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R016
determination method
IMP
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9R016
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R016
determination method
IEA
defense response to bacterium
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity
GOA
curator
UniProt
UniProt protein ID
Q9R016
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R016
determination method
IMP
pyroptosis
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity
GOA
curator
UniProt
UniProt protein ID
Q9R016
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R016
determination method
IMP
detection of bacterium
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity
GOA
curator
UniProt
UniProt protein ID
Q9R016
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R016
determination method
IMP
immune system process
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9R016
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R016
determination method
IEA
apoptotic process
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9R016
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R016
determination method
IEA
protein ubiquitination
determination method
IEA
1 reference
retrieved
24 April 2018
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9R016&geneProductId=UniProtKB:Q9R016
determination method
IEA
positive regulation of canonical Wnt signaling pathway
determination method
IBA
1 reference
retrieved
24 April 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9R016&geneProductId=UniProtKB:Q9R016
determination method
IBA
mitotic spindle assembly
determination method
IBA
1 reference
retrieved
24 April 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9R016&geneProductId=UniProtKB:Q9R016
determination method
IBA
inhibition of cysteine-type endopeptidase activity involved in apoptotic process
determination method
IBA
1 reference
retrieved
24 April 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9R016&geneProductId=UniProtKB:Q9R016
determination method
IBA
negative regulation of apoptotic process
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R016
determination method
IEA
positive regulation of interleukin-1 beta production
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Structural basis for specific flagellin recognition by the NLR protein NAIP5.
GOA
curator
UniProt
UniProt protein ID
Q9R016
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R016
determination method
IDA
defense response to Gram-negative bacterium
determination method
IMP
TAS
2 references
retrieved
8 April 2019
stated in
IAPs: more than just inhibitors of apoptosis proteins
GOA
curator
UniProt
UniProt protein ID
Q9R016
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R016
determination method
TAS
retrieved
8 April 2019
stated in
Structural basis for specific flagellin recognition by the NLR protein NAIP5.
GOA
curator
UniProt
UniProt protein ID
Q9R016
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R016
determination method
IMP
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R016
determination method
IEA
entry of bacterium into host cell
determination method
IDA
IMP
2 references
retrieved
8 April 2019
stated in
Naip5 affects host susceptibility to the intracellular pathogen Legionella pneumophila.
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R016
determination method
IMP
retrieved
8 April 2019
stated in
Naip5 affects host susceptibility to the intracellular pathogen Legionella pneumophila.
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R016
determination method
IDA
has part(s)
BIR repeat
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9R016
NACHT nucleoside triphosphatase domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9R016
Identifiers
RefSeq protein ID
NP_035000
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
17951
XP_011242930
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
17951
XP_011242933
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
17951
XP_011242935
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
17951
XP_017170904
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
17951
XP_017170905
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
17951
XP_017170906
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
17951
XP_036013792
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
17951
UniProt protein ID
Q9R016
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9R016
Ensembl protein ID
ENSMUSP00000058611
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000058611
Sitelinks
Wikipedia
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Wikibooks
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Wikinews
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Wikiquote
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Wikisource
(0 entries)
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Wikiversity
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Multilingual sites
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