(Q21433084)

P-loop containing nucleoside triphosphate hydrolase

1 reference

Winged helix-like DNA-binding domain superfamily

1 reference

Winged helix DNA-binding domain superfamily

1 reference

HRDC-like superfamily

1 reference

Helicase superfamily 1/2, ATP-binding domain, protein family

1 reference

ATP-dependent DNA helicase RecQ, zinc-binding domain, protein family

1 reference

Helicase, C-terminal domain, protein family

1 reference

DEAD/DEAH box helicase

1 reference

HRDC domain, protein family

1 reference

RQC domain, protein family

1 reference

Bloom syndrome protein, BDHCT-box associated domain, protein family

1 reference

BDHCT, protein family

1 reference

DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site, protein family

1 reference

Bloom syndrome protein, N-terminal domain, protein family

1 reference

ATP-dependent DNA/DNA annealing activity

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

G-quadruplex DNA binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

1 reference

9 May 2019

Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

DNA helicase activity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

telomeric D-loop binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

8-hydroxy-2'-deoxyguanosine DNA binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

four-way junction helicase activity

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

ATP-dependent activity, acting on DNA

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

four-way junction DNA binding

3 references

single-stranded DNA binding

3 references

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

3 references

protein homodimerization activity

3 references

3'-5' DNA helicase activity

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

9 May 2019

Point mutations causing Bloom's syndrome abolish ATPase and DNA helicase activities of the BLM protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

forked DNA-dependent helicase activity

3 references

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

Mouse pachytene checkpoint 2 (trip13) is required for completing meiotic recombination but not synapsis

male germ cell nucleus

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

intracellular anatomical structure

IDA

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O88700&geneProductId=UniProtKB:O88700

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

1 reference

9 May 2019

Telomere lengthening early in development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

1 reference

27 March 2018

Telomere lengthening early in development

http://www.ebi.ac.uk/QuickGO/annotations?protein=O88700&geneProductId=UniProtKB:O88700

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

3 references

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

14 February 2019

BLM helicase facilitates telomere replication during leading strand synthesis of telomeres

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

3 references

14 February 2019

BLM helicase facilitates telomere replication during leading strand synthesis of telomeres

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

14 February 2019

Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O88700&geneProductId=UniProtKB:O88700

regulation of cyclin-dependent protein serine/threonine kinase activity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

negative regulation of thymocyte apoptotic process

positive regulation of transcription, DNA-templated

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

negative regulation of cell division

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

positive regulation of alpha-beta T cell proliferation

1 reference

9 May 2019

The Bloom's syndrome helicase is critical for development and function of the alphabeta T-cell lineage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

replication fork processing

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

negative regulation of DNA recombination

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest

regulation of binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

alpha-beta T cell differentiation

IDA

1 reference

9 May 2019

The Bloom's syndrome helicase is critical for development and function of the alphabeta T-cell lineage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

mitotic G2 DNA damage checkpoint signaling

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

1 reference

14 February 2019

Telomere shortening exposes functions for the mouse Werner and Bloom syndrome genes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

3 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O88700&geneProductId=UniProtKB:O88700

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O88700&geneProductId=UniProtKB:O88700

27 March 2018

Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest

http://www.ebi.ac.uk/QuickGO/annotations?protein=O88700&geneProductId=UniProtKB:O88700

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

positive regulation of double-strand break repair via homologous recombination

1 reference

9 May 2019

RECQL5 and BLM exhibit divergent functions in cells defective for the Fanconi anemia pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

replication-born double-strand break repair via sister chromatid exchange

1 reference

9 May 2019

Desialylation of airway epithelial cells during influenza virus infection enhances pneumococcal adhesion via galectin binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

negative regulation of mitotic recombination

6 references

9 May 2019

The GIY-YIG Type Endonuclease Ankyrin Repeat and LEM Domain-Containing Protein 1 (ANKLE1) Is Dispensable for Mouse Hematopoiesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

9 May 2019

Mutation of the murine Bloom's syndrome gene produces global genome destabilization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

9 May 2019

The Bloom's syndrome helicase is critical for development and function of the alphabeta T-cell lineage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

9 May 2019

Stage-specific apoptosis, developmental delay, and embryonic lethality in mice homozygous for a targeted disruption in the murine Bloom's syndrome gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

9 May 2019

Cancer predisposition caused by elevated mitotic recombination in Bloom mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

9 May 2019

The GIY-YIG Type Endonuclease Ankyrin Repeat and LEM Domain-Containing Protein 1 (ANKLE1) Is Dispensable for Mouse Hematopoiesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

4 references

9 May 2019

BLM helicase facilitates telomere replication during leading strand synthesis of telomeres

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

9 May 2019

BLM helicase facilitates telomere replication during leading strand synthesis of telomeres

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O88700&geneProductId=UniProtKB:O88700

G-quadruplex DNA unwinding

3 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O88700&geneProductId=UniProtKB:O88700

27 March 2018

BLM helicase facilitates telomere replication during leading strand synthesis of telomeres

http://www.ebi.ac.uk/QuickGO/annotations?protein=O88700&geneProductId=UniProtKB:O88700

27 March 2018

BLM helicase facilitates telomere replication during leading strand synthesis of telomeres

http://www.ebi.ac.uk/QuickGO/annotations?protein=O88700&geneProductId=UniProtKB:O88700

telomeric D-loop disassembly

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

cellular response to DNA damage stimulus

resolution of meiotic recombination intermediates

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

double-strand break repair via homologous recombination

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

DNA synthesis involved in DNA repair

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

9 May 2019

Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

double-strand break repair via nonhomologous end joining

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

meiotic DNA double-strand break processing involved in reciprocal meiotic recombination

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

negative regulation of apoptotic process

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

G-quadruplex DNA unwinding

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

9 May 2019

BLM helicase facilitates telomere replication during leading strand synthesis of telomeres

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

9 May 2019

BLM helicase facilitates telomere replication during leading strand synthesis of telomeres

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

double-strand break repair via synthesis-dependent strand annealing

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

negative regulation of mitotic recombination

7 references

14 February 2019

The GIY-YIG Type Endonuclease Ankyrin Repeat and LEM Domain-Containing Protein 1 (ANKLE1) Is Dispensable for Mouse Hematopoiesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

14 February 2019

The Bloom's syndrome helicase is critical for development and function of the alphabeta T-cell lineage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

14 February 2019

Stage-specific apoptosis, developmental delay, and embryonic lethality in mice homozygous for a targeted disruption in the murine Bloom's syndrome gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

14 February 2019

Mutation of the murine Bloom's syndrome gene produces global genome destabilization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

14 February 2019

Cancer predisposition caused by elevated mitotic recombination in Bloom mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

14 February 2019

The GIY-YIG Type Endonuclease Ankyrin Repeat and LEM Domain-Containing Protein 1 (ANKLE1) Is Dispensable for Mouse Hematopoiesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

protein complex oligomerization

3 references

protein homooligomerization

3 references

meiotic chromosome separation

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

negative regulation of thymocyte apoptotic process

3 references

14 February 2019

MHC class Ib-restricted CTL provide protection against primary and secondary Listeria monocytogenes infection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

14 February 2019

MHC class Ib-restricted CTL provide protection against primary and secondary Listeria monocytogenes infection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

resolution of recombination intermediates

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

cellular response to ionizing radiation

3 references

cellular response to hydroxyurea

3 references

regulation of DNA-dependent DNA replication

3 references

negative regulation of double-strand break repair via single-strand annealing

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

positive regulation of double-strand break repair via homologous recombination

DNA unwinding involved in DNA replication

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88700

DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site

has part(s)

1 reference

RQC domain

1 reference

Helicase superfamily 1/2, ATP-binding domain

1 reference

DEAD/DEAH box helicase domain

1 reference

ATP-dependent DNA helicase RecQ, zinc-binding domain

1 reference

HRDC domain

1 reference

Bloom syndrome protein, N-terminal domain

1 reference

Bloom syndrome protein, BDHCT-box associated domain

1 reference

Helicase, C-terminal

1 reference

BDHCT

1 reference