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Prolactin family 2, subfamily c, member 2
mammalian protein found in Mus musculus
growth hormone d2
prolactin-2C2
proliferin-1
proliferin
Prl2c2
mitogen-regulated protein 1
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P04095
subclass of
protein
1 reference
stated in
UniProt
retrieved
19 January 2017
UniProt protein ID
P04095
part of
Somatotropin/prolactin
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P04095
four-helical cytokine-like, core
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P04095
Somatotropin hormone, conserved site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
house mouse
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P04095
encoded by
Prl2c2
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P04095
molecular function
growth factor activity
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Stimulation and inhibition of angiogenesis by placental proliferin and proliferin-related protein
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04095
determination method
IDA
protein binding
determination method
IPI
1 reference
retrieved
9 May 2019
stated in
Proliferin secreted by cultured cells binds to mannose 6-phosphate receptors
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04095
determination method
IPI
hormone activity
determination method
IDA
IEA
3 references
retrieved
24 April 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P04095
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P04095&geneProductId=UniProtKB:P04095
determination method
IEA
retrieved
24 April 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P04095&geneProductId=UniProtKB:P04095
determination method
IEA
retrieved
24 April 2018
stated in
Stimulation and inhibition of angiogenesis by placental proliferin and proliferin-related protein
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P04095&geneProductId=UniProtKB:P04095
determination method
IDA
prolactin receptor binding
determination method
IBA
1 reference
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04095
determination method
IBA
hormone activity
determination method
IBA
IDA
IEA
4 references
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P04095
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04095
determination method
IEA
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04095
determination method
IEA
retrieved
9 May 2019
stated in
Stimulation and inhibition of angiogenesis by placental proliferin and proliferin-related protein
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04095
determination method
IDA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04095
determination method
IBA
cell component
extracellular region
determination method
IEA
2 references
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P04095
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04095
determination method
IEA
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04095
determination method
IEA
endoplasmic reticulum
determination method
IDA
IEA
2 references
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P04095
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04095
determination method
IEA
retrieved
9 May 2019
stated in
Proliferin enhances microvilli formation and cell growth of neuroblastoma cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04095
determination method
IDA
extracellular space
determination method
IDA
4 references
retrieved
24 April 2018
stated in
Secretion of proliferin
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P04095&geneProductId=UniProtKB:P04095
determination method
IDA
retrieved
24 April 2018
stated in
Stimulation and inhibition of angiogenesis by placental proliferin and proliferin-related protein
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P04095&geneProductId=UniProtKB:P04095
determination method
IDA
retrieved
24 April 2018
stated in
Proliferin secreted by cultured cells binds to mannose 6-phosphate receptors
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P04095&geneProductId=UniProtKB:P04095
determination method
IDA
retrieved
24 April 2018
stated in
Mrp4, a new mitogen-regulated protein/proliferin gene; unique in this gene family for its expression in the adult mouse tail and ear
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P04095&geneProductId=UniProtKB:P04095
determination method
IDA
extracellular space
determination method
IBA
IDA
5 references
retrieved
9 May 2019
stated in
Secretion of proliferin
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04095
determination method
IDA
retrieved
9 May 2019
stated in
Proliferin secreted by cultured cells binds to mannose 6-phosphate receptors
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04095
determination method
IDA
retrieved
9 May 2019
stated in
Mrp4, a new mitogen-regulated protein/proliferin gene; unique in this gene family for its expression in the adult mouse tail and ear
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04095
determination method
IDA
retrieved
9 May 2019
stated in
Stimulation and inhibition of angiogenesis by placental proliferin and proliferin-related protein
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04095
determination method
IDA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04095
determination method
IBA
biological process
positive regulation of neuroblast proliferation
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Proliferin enhances microvilli formation and cell growth of neuroblastoma cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04095
determination method
IDA
regulation of microvillus assembly
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Proliferin enhances microvilli formation and cell growth of neuroblastoma cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04095
determination method
IDA
negative regulation of myoblast differentiation
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Participation of multiple factors, including proliferin, in the inhibition of myogenic differentiation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04095
determination method
IDA
positive regulation of cell projection organization
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Proliferin enhances microvilli formation and cell growth of neuroblastoma cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04095
determination method
IDA
sprouting angiogenesis
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Stimulation and inhibition of angiogenesis by placental proliferin and proliferin-related protein
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04095
determination method
IDA
positive regulation of blood vessel endothelial cell migration
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Stimulation and inhibition of angiogenesis by placental proliferin and proliferin-related protein
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04095
determination method
IDA
positive regulation of angiogenesis
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Stimulation and inhibition of angiogenesis by placental proliferin and proliferin-related protein
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04095
determination method
IDA
positive regulation of transcription by RNA polymerase II
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Participation of multiple factors, including proliferin, in the inhibition of myogenic differentiation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04095
determination method
IDA
regulation of signaling receptor activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04095
determination method
IEA
female pregnancy
determination method
IBA
1 reference
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04095
determination method
IBA
positive regulation of cell population proliferation
determination method
IBA
1 reference
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04095
determination method
IBA
mammary gland development
determination method
IBA
1 reference
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04095
determination method
IBA
response to nutrient levels
determination method
IBA
1 reference
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04095
determination method
IBA
positive regulation of receptor signaling pathway via JAK-STAT
determination method
IBA
1 reference
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04095
determination method
IBA
positive regulation of lactation
determination method
IBA
1 reference
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04095
determination method
IBA
signal transduction
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04095
determination method
IEA
has part(s)
Somatotropin hormone, conserved site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P04095
Identifiers
RefSeq protein ID
NP_112468
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
18811
XP_006516640
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
18811
XP_017170910
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
18811
UniProt protein ID
P04095
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P04095
Ensembl protein ID
ENSMUSP00000106224
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000106224
ENSMUSP00000152202
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000152202
ENSMUSP00000152254
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000152254
ENSMUSP00000152538
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000152538
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