(Q21491063)

English

NudE neurodevelopment protein 1 like 1

mammalian protein found in Mus musculus

mNudE-L
nuclear distribution gene E-like homolog 1
Ndel1
nuclear distribution protein nudE-like 1
nuclear disribution gene E like
Protein mNudE-like
protein Nudel

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

Nuclear distribution protein nudE-like 1

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9ERR1

NUDE domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

microtubule binding

determination method

1 reference

24 April 2018

A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ERR1&geneProductId=UniProtKB:Q9ERR1

determination method

alpha-tubulin binding

determination method

1 reference

14 February 2019

Nudel binds Cdc42GAP to modulate Cdc42 activity at the leading edge of migrating cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

protein binding

determination method

10 references

14 February 2019

PLEKHM1/DEF8/RAB7 complex regulates lysosome positioning and bone homeostasis.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

14 February 2019

A NUDEL-dependent mechanism of neurofilament assembly regulates the integrity of CNS neurons

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

14 February 2019

DISC1, PDE4B, and NDE1 at the centrosome and synapse

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

14 February 2019

Nudel binds Cdc42GAP to modulate Cdc42 activity at the leading edge of migrating cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

14 February 2019

14-3-3epsilon is important for neuronal migration by binding to NUDEL: a molecular explanation for Miller-Dieker syndrome

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

14 February 2019

NDEL1 phosphorylation by Aurora-A kinase is essential for centrosomal maturation, separation, and TACC3 recruitment

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

14 February 2019

14-3-3epsilon is important for neuronal migration by binding to NUDEL: a molecular explanation for Miller-Dieker syndrome

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

14 February 2019

The structure of the coiled-coil domain of Ndel1 and the basis of its interaction with Lis1, the causal protein of Miller-Dieker lissencephaly

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

14 February 2019

NudE-L, a novel Lis1-interacting protein, belongs to a family of vertebrate coiled-coil proteins

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

14 February 2019

Dixdc1 is a critical regulator of DISC1 and embryonic cortical development

Developmental FunctionaL Annotation at Tufts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

beta-tubulin binding

determination method

1 reference

14 February 2019

Nudel binds Cdc42GAP to modulate Cdc42 activity at the leading edge of migrating cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

identical protein binding

determination method

3 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

14 February 2019

The structure of the coiled-coil domain of Ndel1 and the basis of its interaction with Lis1, the causal protein of Miller-Dieker lissencephaly

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

neurofilament cytoskeleton

determination method

1 reference

14 February 2019

A NUDEL-dependent mechanism of neurofilament assembly regulates the integrity of CNS neurons

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

synaptic vesicle

determination method

1 reference

14 February 2019

DISC1, PDE4B, and NDE1 at the centrosome and synapse

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

microtubule associated complex

determination method

1 reference

14 February 2019

A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

cell leading edge

determination method

1 reference

14 February 2019

Nudel binds Cdc42GAP to modulate Cdc42 activity at the leading edge of migrating cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

determination method

1 reference

14 February 2019

An essential role of the aPKC-Aurora A-NDEL1 pathway in neurite elongation by modulation of microtubule dynamics

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

chromosome, centromeric region

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

determination method

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

determination method

4 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

determination method

3 references

determination method

8 references

24 April 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ERR1&geneProductId=UniProtKB:Q9ERR1

determination method

24 April 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ERR1&geneProductId=UniProtKB:Q9ERR1

determination method

24 April 2018

DISC1, PDE4B, and NDE1 at the centrosome and synapse

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ERR1&geneProductId=UniProtKB:Q9ERR1

determination method

24 April 2018

NUDEL is a novel Cdk5 substrate that associates with LIS1 and cytoplasmic dynein

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ERR1&geneProductId=UniProtKB:Q9ERR1

determination method

24 April 2018

Recruitment of katanin p60 by phosphorylated NDEL1, an LIS1 interacting protein, is essential for mitotic cell division and neuronal migration

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ERR1&geneProductId=UniProtKB:Q9ERR1

determination method

24 April 2018

A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ERR1&geneProductId=UniProtKB:Q9ERR1

determination method

24 April 2018

NDEL1 phosphorylation by Aurora-A kinase is essential for centrosomal maturation, separation, and TACC3 recruitment

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ERR1&geneProductId=UniProtKB:Q9ERR1

determination method

24 April 2018

Insulin signaling regulates a functional interaction between adenomatous polyposis coli and cytoplasmic dynein

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ERR1&geneProductId=UniProtKB:Q9ERR1

determination method

determination method

2 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

kinesin complex

determination method

3 references

determination method

3 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

14 February 2019

Recruitment of katanin p60 by phosphorylated NDEL1, an LIS1 interacting protein, is essential for mitotic cell division and neuronal migration

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

determination method

2 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

determination method

9 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

14 February 2019

Recruitment of katanin p60 by phosphorylated NDEL1, an LIS1 interacting protein, is essential for mitotic cell division and neuronal migration

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

14 February 2019

DISC1, PDE4B, and NDE1 at the centrosome and synapse

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

14 February 2019

NUDEL is a novel Cdk5 substrate that associates with LIS1 and cytoplasmic dynein

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

14 February 2019

NDEL1 phosphorylation by Aurora-A kinase is essential for centrosomal maturation, separation, and TACC3 recruitment

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

14 February 2019

A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

14 February 2019

Insulin signaling regulates a functional interaction between adenomatous polyposis coli and cytoplasmic dynein

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

biological process

retrograde axonal transport

determination method

1 reference

14 February 2019

A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

cell differentiation

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

vesicle transport along microtubule

determination method

1 reference

24 April 2018

Complete loss of Ndel1 results in neuronal migration defects and early embryonic lethality

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ERR1&geneProductId=UniProtKB:Q9ERR1

determination method

activation of GTPase activity

determination method

1 reference

14 February 2019

Nudel binds Cdc42GAP to modulate Cdc42 activity at the leading edge of migrating cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

centrosome localization

determination method

1 reference

24 April 2018

Nudel binds Cdc42GAP to modulate Cdc42 activity at the leading edge of migrating cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ERR1&geneProductId=UniProtKB:Q9ERR1

determination method

neuron migration

determination method

1 reference

14 February 2019

Complete loss of Ndel1 results in neuronal migration defects and early embryonic lethality

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

nervous system development

determination method

2 references

neuron projection extension

determination method

1 reference

14 February 2019

An essential role of the aPKC-Aurora A-NDEL1 pathway in neurite elongation by modulation of microtubule dynamics

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

inner cell mass cell proliferation

determination method

1 reference

14 February 2019

Complete loss of Ndel1 results in neuronal migration defects and early embryonic lethality

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

multicellular organism development

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

canonical Wnt signaling pathway

determination method

1 reference

14 February 2019

Dixdc1 is a critical regulator of DISC1 and embryonic cortical development

Developmental FunctionaL Annotation at Tufts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

cerebral cortex radially oriented cell migration

determination method

1 reference

14 February 2019

Dixdc1 is a critical regulator of DISC1 and embryonic cortical development

Developmental FunctionaL Annotation at Tufts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

determination method

1 reference

24 April 2018

Nudel binds Cdc42GAP to modulate Cdc42 activity at the leading edge of migrating cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ERR1&geneProductId=UniProtKB:Q9ERR1

determination method

central nervous system neuron axonogenesis

determination method

1 reference

14 February 2019

A NUDEL-dependent mechanism of neurofilament assembly regulates the integrity of CNS neurons

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

mitotic centrosome separation

determination method

3 references

24 April 2018

NDEL1 phosphorylation by Aurora-A kinase is essential for centrosomal maturation, separation, and TACC3 recruitment

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ERR1&geneProductId=UniProtKB:Q9ERR1

determination method

24 April 2018

NDEL1 phosphorylation by Aurora-A kinase is essential for centrosomal maturation, separation, and TACC3 recruitment

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ERR1&geneProductId=UniProtKB:Q9ERR1

determination method

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ERR1&geneProductId=UniProtKB:Q9ERR1

determination method

determination method

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

establishment of mitotic spindle orientation

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

microtubule nucleation

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

chromosome segregation

determination method

3 references

insulin receptor signaling pathway

determination method

1 reference

14 February 2019

Insulin signaling regulates a functional interaction between adenomatous polyposis coli and cytoplasmic dynein

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

establishment of chromosome localization

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

lysosome localization

determination method

1 reference

14 February 2019

PLEKHM1/DEF8/RAB7 complex regulates lysosome positioning and bone homeostasis.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

positive regulation of ruffle assembly

determination method

1 reference

14 February 2019

PLEKHM1/DEF8/RAB7 complex regulates lysosome positioning and bone homeostasis.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

regulation of neuron projection development

determination method

3 references

24 April 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ERR1&geneProductId=UniProtKB:Q9ERR1

determination method

24 April 2018

Disrupted-In-Schizophrenia 1 regulates integration of newly generated neurons in the adult brain

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ERR1&geneProductId=UniProtKB:Q9ERR1

determination method

24 April 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ERR1&geneProductId=UniProtKB:Q9ERR1

determination method

mitotic centrosome separation

determination method

4 references

14 February 2019

NDEL1 phosphorylation by Aurora-A kinase is essential for centrosomal maturation, separation, and TACC3 recruitment

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

14 February 2019

NDEL1 phosphorylation by Aurora-A kinase is essential for centrosomal maturation, separation, and TACC3 recruitment

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

regulation of neuron projection development

determination method

4 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

14 February 2019

Disrupted-In-Schizophrenia 1 regulates integration of newly generated neurons in the adult brain

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERR1

determination method

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9ERR1

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000018880

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000018880

ENSMUSP00000098579

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000098579

ENSMUSP00000104312

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000104312

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q21491063&oldid=2023101306"