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(Q21493965)
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Basic helix-loop-helix family, member e22
mammalian protein found in Mus musculus
Bhlhe22
basic helix-loop-helix (bHLH) gene, class B, beta3
class B basic helix-loop-helix protein 5
class E basic helix-loop-helix protein 22
Protein BETA3
bHLHb5
basic helix-loop-helix domain containing, class B5
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q8C6A8
subclass of
protein
1 reference
stated in
UniProt
retrieved
19 January 2017
UniProt protein ID
Q8C6A8
part of
Class E basic helix-loop-helix protein 22
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8C6A8
Helix-loop-helix DNA-binding domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8C6A8
Myc-type, basic helix-loop-helix (bHLH) domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
house mouse
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q8C6A8
encoded by
Bhlhe22
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q8C6A8
molecular function
DNA-binding transcription factor activity, RNA polymerase II-specific
determination method
IEA
IMP
2 references
retrieved
14 February 2019
stated in
Bhlhb5 and Prdm8 form a repressor complex involved in neuronal circuit assembly
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C6A8
determination method
IMP
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C6A8
determination method
IEA
chromatin binding
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
Bhlhb5 and Prdm8 form a repressor complex involved in neuronal circuit assembly
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C6A8
determination method
IDA
protein binding
determination method
IPI
1 reference
retrieved
14 February 2019
stated in
Bhlhb5 and Prdm8 form a repressor complex involved in neuronal circuit assembly
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C6A8
determination method
IPI
protein homodimerization activity
determination method
IPI
1 reference
retrieved
14 February 2019
stated in
Bhlhb5 and Prdm8 form a repressor complex involved in neuronal circuit assembly
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C6A8
determination method
IPI
protein dimerization activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C6A8
determination method
IEA
cell component
nucleus
determination method
IDA
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8C6A8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C6A8
determination method
IEA
retrieved
14 February 2019
stated in
Bhlhb5 and Prdm8 form a repressor complex involved in neuronal circuit assembly
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C6A8
determination method
IDA
biological process
anterior commissure morphogenesis
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Bhlhb5 and Prdm8 form a repressor complex involved in neuronal circuit assembly
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C6A8
determination method
IMP
corpus callosum morphogenesis
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Bhlhb5 and Prdm8 form a repressor complex involved in neuronal circuit assembly
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C6A8
determination method
IMP
corticospinal tract morphogenesis
determination method
IGI
IMP
2 references
retrieved
14 February 2019
stated in
Bhlhb5 and Prdm8 form a repressor complex involved in neuronal circuit assembly
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C6A8
determination method
IMP
retrieved
14 February 2019
stated in
Bhlhb5 and Prdm8 form a repressor complex involved in neuronal circuit assembly
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C6A8
determination method
IGI
neurogenesis
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C6A8
determination method
IEA
retina morphogenesis in camera-type eye
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Requirement for Bhlhb5 in the specification of amacrine and cone bipolar subtypes in mouse retina
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C6A8
determination method
IMP
negative regulation of transcription, DNA-templated
determination method
IDA
IMP
2 references
retrieved
14 February 2019
stated in
Bhlhb5 and Prdm8 form a repressor complex involved in neuronal circuit assembly
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C6A8
determination method
IMP
retrieved
14 February 2019
stated in
Functional and structural characterization of the human gene BHLHB5, encoding a basic helix-loop-helix transcription factor
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C6A8
determination method
IDA
regulation of transcription, DNA-templated
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C6A8
determination method
IEA
central nervous system projection neuron axonogenesis
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Bhlhb5 and Prdm8 form a repressor complex involved in neuronal circuit assembly
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C6A8
determination method
IMP
cerebral cortex regionalization
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
The protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C6A8
determination method
IMP
transcription, DNA-templated
determination method
IEA
1 reference
retrieved
27 March 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q8C6A8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8C6A8&geneProductId=UniProtKB:Q8C6A8
determination method
IEA
nervous system development
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8C6A8
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C6A8
determination method
IEA
neuron differentiation
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Requirement for Bhlhb5 in the specification of amacrine and cone bipolar subtypes in mouse retina
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C6A8
determination method
IMP
retinal bipolar neuron differentiation
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Requirement for Bhlhb5 in the specification of amacrine and cone bipolar subtypes in mouse retina
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C6A8
determination method
IMP
regulation of transcription by RNA polymerase II
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C6A8
determination method
IEA
has part(s)
Myc-type, basic helix-loop-helix (bHLH) domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8C6A8
Identifiers
RefSeq protein ID
NP_067535
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
59058
UniProt protein ID
Q8C6A8
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q8C6A8
Ensembl protein ID
ENSMUSP00000026120
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000026120
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