Wikidata

(Q21494909)

English

Toll-like receptor adaptor molecule 1

mammalian protein found in Mus musculus

  • TIR domain-containing adapter molecule 1
  • TIR domain-containing adapter protein inducing IFN-beta
  • TIR domain-containing adaptor inducing interferon-beta
  • Ticam1
  • toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta
In more languages

Statements

molecular function
protein binding
determination method
IPI
12 references
stated in
UniProt
UniProt protein ID
Q80UF7
retrieved
9 August 2016
language of work or name
English
retrieved
14 February 2019
stated in
FLN29 deficiency reveals its negative regulatory role in the Toll-like receptor (TLR) and retinoic acid-inducible gene I (RIG-I)-like helicase signaling pathway
GOA
curator
UniProt
UniProt protein ID
Q80UF7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80UF7
determination method
IPI
retrieved
14 February 2019
stated in
WDFY1 mediates TLR3/4 signaling by recruiting TRIF
GOA
curator
UniProt
UniProt protein ID
Q80UF7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80UF7
determination method
IPI
retrieved
14 February 2019
stated in
Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6
GOA
curator
UniProt
UniProt protein ID
Q80UF7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80UF7
determination method
IPI
retrieved
14 February 2019
stated in
DDX1, DDX21, and DHX36 helicases form a complex with the adaptor molecule TRIF to sense dsRNA in dendritic cells
GOA
curator
UniProt
UniProt protein ID
Q80UF7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80UF7
determination method
IPI
retrieved
14 February 2019
stated in
Peli1 facilitates TRIF-dependent Toll-like receptor signaling and proinflammatory cytokine production
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80UF7
determination method
IPI
retrieved
14 February 2019
stated in
Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80UF7
determination method
IPI
retrieved
14 February 2019
stated in
Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80UF7
determination method
IPI
retrieved
14 February 2019
stated in
Integrin CD11b negatively regulates TLR-triggered inflammatory responses by activating Syk and promoting degradation of MyD88 and TRIF via Cbl-b
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80UF7
determination method
IPI
retrieved
14 February 2019
stated in
Intracellular MHC class II molecules promote TLR-triggered innate immune responses by maintaining activation of the kinase Btk
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80UF7
determination method
IPI
retrieved
14 February 2019
stated in
Bruton's tyrosine kinase phosphorylates Toll-like receptor 3 to initiate antiviral response
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80UF7
determination method
IPI
retrieved
14 February 2019
stated in
LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80UF7
determination method
IPI
cell component
biological process
response to exogenous dsRNA
determination method
IDA
IEA
IMP
ISO
8 references
stated in
UniProt
UniProt protein ID
Q80UF7
retrieved
9 August 2016
language of work or name
English
retrieved
14 February 2019
stated in
Raftlin is involved in the nucleocapture complex to induce poly(I:C)-mediated TLR3 activation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80UF7
determination method
ISO
retrieved
14 February 2019
stated in
DDX1, DDX21, and DHX36 helicases form a complex with the adaptor molecule TRIF to sense dsRNA in dendritic cells
GOA
curator
UniProt
UniProt protein ID
Q80UF7
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80UF7
determination method
IMP
retrieved
14 February 2019
stated in
DDX1, DDX21, and DHX36 helicases form a complex with the adaptor molecule TRIF to sense dsRNA in dendritic cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80UF7
determination method
IMP
retrieved
14 February 2019
stated in
Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80UF7
determination method
IMP
retrieved
14 February 2019
stated in
Identification of Lps2 as a key transducer of MyD88-independent TIR signalling
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80UF7
determination method
IMP
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80UF7
determination method
IEA
retrieved
14 February 2019
stated in
Identification of Lps2 as a key transducer of MyD88-independent TIR signalling
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80UF7
determination method
IDA

Identifiers

 
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