(Q21494990)

English

Cyclin E1

mammalian protein found in Mus musculus

G1/S-specific cyclin-E1
Ccne1

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

kinase activity

determination method

1 reference

9 May 2019

GADD45b and GADD45g are cdc2/cyclinB1 kinase inhibitors with a role in S and G2/M cell cycle checkpoints induced by genotoxic stress

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

cyclin-dependent protein serine/threonine kinase regulator activity

determination method

1 reference

24 April 2018

Deletion of Mnt leads to disrupted cell cycle control and tumorigenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61457&geneProductId=UniProtKB:Q61457

determination method

protein binding

determination method

6 references

9 May 2019

Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

9 May 2019

Ciz1 cooperates with cyclin-A-CDK2 to activate mammalian DNA replication in vitro

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

9 May 2019

Caspase-3 regulates cell cycle in B cells: a consequence of substrate specificity

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

9 May 2019

Genetic analysis of Ras signalling pathways in cell proliferation, migration and survival.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

9 May 2019

Cyclin A is redundant in fibroblasts but essential in hematopoietic and embryonic stem cells

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

9 May 2019

Cdk1 is sufficient to drive the mammalian cell cycle

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

protein-containing complex binding

determination method

1 reference

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

protein kinase activity

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

protein kinase binding

determination method

3 references

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

9 May 2019

The p21(Cip1) protein, a cyclin inhibitor, regulates the levels and the intracellular localization of CDC25A in mice regenerating livers

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

cyclin-dependent protein kinase holoenzyme complex

determination method

1 reference

24 April 2018

Caspase-3 regulates cell cycle in B cells: a consequence of substrate specificity

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61457&geneProductId=UniProtKB:Q61457

determination method

cyclin E1-CDK2 complex

determination method

1 reference

24 April 2018

Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61457&geneProductId=UniProtKB:Q61457

determination method

determination method

6 references

24 April 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61457&geneProductId=UniProtKB:Q61457

determination method

24 April 2018

The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61457&geneProductId=UniProtKB:Q61457

determination method

24 April 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61457&geneProductId=UniProtKB:Q61457

determination method

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61457&geneProductId=UniProtKB:Q61457

determination method

24 April 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61457&geneProductId=UniProtKB:Q61457

determination method

24 April 2018

Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61457&geneProductId=UniProtKB:Q61457

determination method

determination method

1 reference

24 April 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61457&geneProductId=UniProtKB:Q61457

determination method

determination method

1 reference

24 April 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61457&geneProductId=UniProtKB:Q61457

determination method

determination method

7 references

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

9 May 2019

The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

9 May 2019

Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

cyclin E1-CDK2 complex

determination method

3 references

7 November 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61457&geneProductId=UniProtKB:Q61457

determination method

7 November 2018

Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61457&geneProductId=UniProtKB:Q61457

determination method

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61457&geneProductId=UniProtKB:Q61457

determination method

cyclin E1-CDK2 complex

determination method

4 references

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

9 May 2019

Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

biological process

Wnt signaling pathway

determination method

1 reference

9 May 2019

A functional link between Wnt signaling and SKP2-independent p27 turnover in mammary tumors

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

DNA replication initiation

determination method

1 reference

9 May 2019

Cyclin E ablation in the mouse

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

protein phosphorylation

determination method

3 references

9 May 2019

Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

9 May 2019

GADD45b and GADD45g are cdc2/cyclinB1 kinase inhibitors with a role in S and G2/M cell cycle checkpoints induced by genotoxic stress

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

telomere maintenance

determination method

1 reference

9 May 2019

Mammalian E-type cyclins control chromosome pairing, telomere stability and CDK2 localization in male meiosis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

regulation of protein kinase activity

determination method

1 reference

24 April 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61457&geneProductId=UniProtKB:Q61457

determination method

chromosome organization involved in meiotic cell cycle

determination method

1 reference

9 May 2019

Mammalian E-type cyclins control chromosome pairing, telomere stability and CDK2 localization in male meiosis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

homologous chromosome pairing at meiosis

determination method

1 reference

9 May 2019

Mammalian E-type cyclins control chromosome pairing, telomere stability and CDK2 localization in male meiosis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

negative regulation of transcription by RNA polymerase II

determination method

1 reference

9 May 2019

Regulation of the retinoblastoma protein-related p107 by G1 cyclin complexes

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

G1/S transition of mitotic cell cycle

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

positive regulation of cell differentiation

determination method

1 reference

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

regulation of cyclin-dependent protein serine/threonine kinase activity

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

mitotic cell cycle

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

regulation of mitotic nuclear division

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

positive regulation of cell population proliferation

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

positive regulation of cell cycle

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

positive regulation of G1/S transition of mitotic cell cycle

determination method

1 reference

7 November 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61457&geneProductId=UniProtKB:Q61457

determination method

mitotic cell cycle phase transition

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61457

determination method

Cyclin, C-terminal domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61457

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61457

Cyclin, N-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q61457

Identifiers

RefSeq protein ID

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000103658

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000103658

ENSMUSP00000117662

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000117662

ENSMUSP00000145532

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000145532

Sitelinks

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Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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