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(Q21495047)
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Cyclin dependent kinase inhibitor 2C
mammalian protein found in Mus musculus
Cdkn2c
p18-INK4c
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
cyclin-dependent kinase 6 inhibitor
p18-INK6
cyclin-dependent kinase 4 inhibitor C
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q60772
subclass of
protein
1 reference
stated in
UniProt
retrieved
19 January 2017
UniProt protein ID
Q60772
part of
Ankyrin repeat-containing domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q60772
Ankyrin repeat-containing domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Ankyrin repeat, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
house mouse
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q60772
encoded by
Cdkn2c
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q60772
molecular function
cyclin-dependent protein serine/threonine kinase inhibitor activity
determination method
IEA
ISO
IDA
3 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60772
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60772
determination method
IEA
retrieved
14 February 2019
stated in
Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60772
determination method
IDA
protein kinase binding
determination method
IEA
ISO
IPI
3 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60772
determination method
ISO
retrieved
14 February 2019
stated in
Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60772
determination method
IPI
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60772
determination method
IEA
cell component
cytoplasm
determination method
IEA
ISO
2 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60772
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60772
determination method
IEA
nucleus
determination method
IEA
ISO
2 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60772
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60772
determination method
IEA
biological process
cell cycle
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q60772
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60772
determination method
IEA
regulation of cyclin-dependent protein serine/threonine kinase activity
determination method
IEA
ISO
2 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60772
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60772
determination method
IEA
negative regulation of phosphorylation
determination method
IEA
ISO
2 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60772
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60772
determination method
IEA
oligodendrocyte differentiation
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60772
determination method
IEA
negative regulation of cell growth
determination method
IEA
ISO
2 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60772
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60772
determination method
IEA
negative regulation of cell population proliferation
determination method
IGI
IEA
ISO
3 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60772
determination method
ISO
retrieved
14 February 2019
stated in
p18Ink4c collaborates with Men1 to constrain lung stem cell expansion and suppress non-small-cell lung cancers
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60772
determination method
IGI
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60772
determination method
IEA
negative regulation of cyclin-dependent protein serine/threonine kinase activity
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60772
determination method
IDA
G1/S transition of mitotic cell cycle
determination method
IEA
ISO
2 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60772
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60772
determination method
IEA
has part(s)
ankyrin repeat-containing domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q60772
ankyrin repeat
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q60772
Identifiers
RefSeq protein ID
NP_001288297
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
12580
NP_031697
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
12580
UniProt protein ID
Q60772
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q60772
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