(Q21495127)

http://www.ebi.ac.uk/interpro/protein/O89098

cystatins

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

peptidase inhibitor activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89098

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O89098&geneProductId=UniProtKB:O89098

cysteine-type endopeptidase inhibitor activity

IBA

IBA

cysteine-type endopeptidase inhibitor activity

3 references

9 May 2019

The balance between cathepsin C and cystatin F controls remyelination in the brain of Plp1-overexpressing mouse, a chronic demyelinating disease model.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89098

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89098

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89098

peptidase inhibitor activity

IDA

protein homodimerization activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89098

peptidase inhibitor activity

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89098

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89098

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89098

9 May 2019

Cystatin F is a cathepsin C-directed protease inhibitor regulated by proteolysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89098

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89098

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O89098&geneProductId=UniProtKB:O89098

1 reference

14 February 2019

Cystatin F is a biomarker of prion pathogenesis in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89098

1 reference

9 May 2019

The balance between cathepsin C and cystatin F controls remyelination in the brain of Plp1-overexpressing mouse, a chronic demyelinating disease model.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89098

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89098

1 reference

9 May 2019

Cystatin F is secreted, but artificial modification of its C-terminus can induce its endocytic targeting

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89098

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89098

endoplasmic reticulum

negative regulation of peptidase activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89098

negative regulation of cysteine-type endopeptidase activity

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O89098&geneProductId=UniProtKB:O89098

negative regulation of endopeptidase activity

IBA

1 reference

14 January 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=O89098&geneProductId=UniProtKB:O89098

positive regulation of myelination

1 reference

9 May 2019

The balance between cathepsin C and cystatin F controls remyelination in the brain of Plp1-overexpressing mouse, a chronic demyelinating disease model.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89098

inhibition of cysteine-type endopeptidase activity

IMP

1 reference

9 May 2019

The balance between cathepsin C and cystatin F controls remyelination in the brain of Plp1-overexpressing mouse, a chronic demyelinating disease model.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89098

negative regulation of microglial cell activation

IMP

1 reference

9 May 2019

The balance between cathepsin C and cystatin F controls remyelination in the brain of Plp1-overexpressing mouse, a chronic demyelinating disease model.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89098

negative regulation of peptidase activity

IMP

IDA

negative regulation of peptidase activity

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89098

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89098

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89098

9 May 2019

Cystatin F is a cathepsin C-directed protease inhibitor regulated by proteolysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89098

1 reference

InterPro Release 71.0