(Q21495548)

English

Ephrin B2

mammalian protein found in Mus musculus

Efnb2
HTK-L
HTK ligand
ELF-2
EPH-related receptor tyrosine kinase ligand 5
ephrin-B2
LERK-5

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

signaling receptor binding

determination method

1 reference

14 February 2019

Crystal structure of an Eph receptor-ephrin complex

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

protein binding

determination method

3 references

14 February 2019

The amyotrophic lateral sclerosis 8 protein VAPB is cleaved, secreted, and acts as a ligand for Eph receptors

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

14 February 2019

Metalloproteinase/Presenilin1 processing of ephrinB regulates EphB-induced Src phosphorylation and signaling

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

14 February 2019

Spatial regulation of VEGF receptor endocytosis in angiogenesis

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

ephrin receptor binding

determination method

4 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

protein tyrosine kinase activity

determination method

1 reference

14 January 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P52800&geneProductId=UniProtKB:P52800

determination method

integral component of membrane

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

determination method

2 references

plasma membrane

determination method

4 references

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P52800&geneProductId=UniProtKB:P52800

determination method

31 January 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P52800&geneProductId=UniProtKB:P52800

determination method

31 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P52800&geneProductId=UniProtKB:P52800

determination method

31 January 2018

Bidirectional signaling mediated by ephrin-B2 and EphB2 controls urorectal development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P52800&geneProductId=UniProtKB:P52800

determination method

plasma membrane

determination method

3 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P52800&geneProductId=UniProtKB:P52800

determination method

21 June 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P52800&geneProductId=UniProtKB:P52800

determination method

21 June 2018

Bidirectional signaling mediated by ephrin-B2 and EphB2 controls urorectal development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P52800&geneProductId=UniProtKB:P52800

determination method

plasma membrane

determination method

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

14 February 2019

Bidirectional signaling mediated by ephrin-B2 and EphB2 controls urorectal development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

glutamatergic synapse

determination method

8 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

14 February 2019

Serine phosphorylation of ephrinB2 regulates trafficking of synaptic AMPA receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

14 February 2019

The receptor tyrosine kinase EphB2 regulates NMDA-dependent synaptic function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

14 February 2019

Serine phosphorylation of ephrinB2 regulates trafficking of synaptic AMPA receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

14 February 2019

Hippocampal plasticity requires postsynaptic ephrinBs.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

14 February 2019

The receptor tyrosine kinase EphB2 regulates NMDA-dependent synaptic function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

14 February 2019

Serine phosphorylation of ephrinB2 regulates trafficking of synaptic AMPA receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

integral component of postsynaptic density membrane

determination method

1 reference

14 February 2019

Hippocampal plasticity requires postsynaptic ephrinBs.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

biological process

positive regulation of aorta morphogenesis

determination method

1 reference

14 February 2019

Artery and vein size is balanced by Notch and ephrin B2/EphB4 during angiogenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

cell differentiation

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

blood vessel morphogenesis

determination method

1 reference

21 June 2018

Transient expression of ephrin b2 in perinatal skin is required for maintenance of keratinocyte homeostasis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P52800&geneProductId=UniProtKB:P52800

determination method

negative regulation of keratinocyte proliferation

determination method

1 reference

14 February 2019

Transient expression of ephrin b2 in perinatal skin is required for maintenance of keratinocyte homeostasis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

regulation of chemotaxis

determination method

3 references

venous blood vessel morphogenesis

determination method

1 reference

14 February 2019

Artery and vein size is balanced by Notch and ephrin B2/EphB4 during angiogenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

T cell costimulation

determination method

1 reference

14 February 2019

EphB6-null mutation results in compromised T cell function

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

lymph vessel development

determination method

1 reference

14 February 2019

PDZ interaction site in ephrinB2 is required for the remodeling of lymphatic vasculature

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

nervous system development

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

cell migration involved in sprouting angiogenesis

determination method

3 references

multicellular organism development

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

determination method

3 references

nephric duct morphogenesis

determination method

1 reference

14 February 2019

Nephric duct insertion requires EphA4/EphA7 signaling from the pericloacal mesenchyme

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

animal organ morphogenesis

determination method

1 reference

14 February 2019

Bidirectional signaling mediated by ephrin-B2 and EphB2 controls urorectal development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

positive regulation of cardiac muscle cell differentiation

determination method

1 reference

14 February 2019

Notch signaling is essential for ventricular chamber development

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

determination method

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P52800&geneProductId=UniProtKB:P52800

determination method

ephrin receptor signaling pathway

determination method

5 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

positive regulation of cell population proliferation

determination method

1 reference

21 June 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P52800&geneProductId=UniProtKB:P52800

determination method

negative regulation of neuron projection development

determination method

1 reference

21 June 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P52800&geneProductId=UniProtKB:P52800

determination method

peptidyl-tyrosine phosphorylation

determination method

1 reference

14 January 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P52800&geneProductId=UniProtKB:P52800

determination method

positive regulation of neuron death

determination method

1 reference

21 June 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P52800&geneProductId=UniProtKB:P52800

determination method

regulation of postsynaptic neurotransmitter receptor internalization

determination method

3 references

14 February 2019

Serine phosphorylation of ephrinB2 regulates trafficking of synaptic AMPA receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

14 February 2019

Serine phosphorylation of ephrinB2 regulates trafficking of synaptic AMPA receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

14 February 2019

Serine phosphorylation of ephrinB2 regulates trafficking of synaptic AMPA receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52800

determination method

Ephrin, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P52800

Ephrin receptor-binding domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P52800

Ephrin-B ectodomain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P52800

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000001319

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000001319

ENSMUSP00000116027

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000116027

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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