(Q21495895)

Ribosomal protein S5 domain 2-type fold

1 reference

Impact family

1 reference

Ubiquitin-conjugating enzyme/RWD-like

1 reference

RWD domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Impact, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Uncharacterised protein family UPF0029, Impact, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

12 September 2018

1 reference

12 September 2018

1 reference

14 February 2019

Evidence that Yih1 resides in a complex with ribosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55091

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55091

1 reference

14 February 2019

IMPACT is a developmentally regulated protein in neurons that opposes the eukaryotic initiation factor 2α kinase GCN2 in the modulation of neurite outgrowth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55091

negative regulation of transcription from RNA polymerase II promoter in response to stress

biological process

1 reference

14 February 2019

Evolutionarily conserved IMPACT impairs various stress responses that require GCN1 for activating the eIF2 kinase GCN2.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55091

negative regulation of protein phosphorylation

3 references

14 February 2019

IMPACT is a developmentally regulated protein in neurons that opposes the eukaryotic initiation factor 2α kinase GCN2 in the modulation of neurite outgrowth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55091

14 February 2019

Evolutionarily conserved IMPACT impairs various stress responses that require GCN1 for activating the eIF2 kinase GCN2.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55091

14 February 2019

IMPACT, a protein preferentially expressed in the mouse brain, binds GCN1 and inhibits GCN2 activation

GOA

curator

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55091

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55091

positive regulation of translational initiation in response to starvation

IEA

1 reference

14 February 2019

IMPACT is a developmentally regulated protein in neurons that opposes the eukaryotic initiation factor 2α kinase GCN2 in the modulation of neurite outgrowth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55091

cellular response to glucose starvation

1 reference

14 February 2019

Evolutionarily conserved IMPACT impairs various stress responses that require GCN1 for activating the eIF2 kinase GCN2.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55091

negative regulation of protein autophosphorylation

negative regulation of protein-containing complex assembly

1 reference

14 February 2019

Evolutionarily conserved IMPACT impairs various stress responses that require GCN1 for activating the eIF2 kinase GCN2.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55091

cellular response to amino acid starvation

1 reference

14 February 2019

Evolutionarily conserved IMPACT impairs various stress responses that require GCN1 for activating the eIF2 kinase GCN2.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55091

cellular response to acidic pH

1 reference

14 February 2019

Evolutionarily conserved IMPACT impairs various stress responses that require GCN1 for activating the eIF2 kinase GCN2.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55091

cellular response to benomyl

1 reference

14 February 2019

Evolutionarily conserved IMPACT impairs various stress responses that require GCN1 for activating the eIF2 kinase GCN2.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55091

negative regulation of transcription by RNA polymerase II

1 reference

14 February 2019

IMPACT is a developmentally regulated protein in neurons that opposes the eukaryotic initiation factor 2α kinase GCN2 in the modulation of neurite outgrowth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55091

negative regulation of cell death

1 reference

14 February 2019

Evolutionarily conserved IMPACT impairs various stress responses that require GCN1 for activating the eIF2 kinase GCN2.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55091

nervous system development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55091

neuron projection extension

IEA

1 reference

14 February 2019

IMPACT is a developmentally regulated protein in neurons that opposes the eukaryotic initiation factor 2α kinase GCN2 in the modulation of neurite outgrowth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55091

cellular response to leucine starvation

1 reference

14 February 2019

IMPACT is a developmentally regulated protein in neurons that opposes the eukaryotic initiation factor 2α kinase GCN2 in the modulation of neurite outgrowth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55091

positive regulation of neuron differentiation

1 reference

14 February 2019

IMPACT is a developmentally regulated protein in neurons that opposes the eukaryotic initiation factor 2α kinase GCN2 in the modulation of neurite outgrowth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55091

cellular response to UV-C

1 reference

14 February 2019

Evolutionarily conserved IMPACT impairs various stress responses that require GCN1 for activating the eIF2 kinase GCN2.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55091

regulation of translation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55091

regulation of translational initiation

IEA

1 reference

14 February 2019

IMPACT, a protein preferentially expressed in the mouse brain, binds GCN1 and inhibits GCN2 activation

GOA

curator

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55091

cellular response to hydrogen peroxide

1 reference

14 February 2019

Evolutionarily conserved IMPACT impairs various stress responses that require GCN1 for activating the eIF2 kinase GCN2.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55091

Uncharacterised protein family UPF0029, Impact, conserved site

has part(s)

1 reference

RWD domain

1 reference

Impact, N-terminal

1 reference