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Multiple EGF-like-domains 8
mammalian protein found in Mus musculus
EGF-like-domain, multiple 4
Megf8
multiple EGF-like domains protein 8
EGF-like protein 4
epidermal growth factor-like protein 4
multiple epidermal growth factor-like domains protein 8
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P60882
part of
Spermadhesin, CUB domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P60882
Kelch-type beta propeller
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P60882
membrane protein
1 reference
based on heuristic
inferred from GOA cell component → membrane
CUB domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Laminin EGF domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
EGF-like calcium-binding domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
PSI domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
EGF domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
EGF-like domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
EGF-like, conserved site, protein family
1 reference
based on heuristic
inferred from protein domain or family
Plexin repeat, protein family
1 reference
based on heuristic
inferred from protein domain or family
EGF-like calcium-binding, conserved site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
house mouse
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P60882
encoded by
Megf8
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P60882
molecular function
calcium ion binding
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
IEA
molecular function
determination method
ND
1 reference
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
ND
cell component
integral component of membrane
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P60882
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
IEA
nucleus
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Massively parallel sequencing identifies the gene Megf8 with ENU-induced mutation causing heterotaxy
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
IDA
membrane
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P60882
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
IEA
biological process
embryonic skeletal system morphogenesis
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
MEGF8 is a modifier of BMP signaling in trigeminal sensory neurons
GOA
curator
UniProt
UniProt protein ID
P60882
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
IMP
epiboly involved in gastrulation with mouth forming second
determination method
IEA
ISO
2 references
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
ISO
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
IEA
determination of heart left/right asymmetry
determination method
IEA
IMP
ISO
3 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
ISO
retrieved
14 February 2019
stated in
Mouse model of heterotaxy with single ventricle spectrum of cardiac anomalies
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
IMP
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
IEA
limb morphogenesis
determination method
IEA
ISO
2 references
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
ISO
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
IEA
embryonic heart tube left/right pattern formation
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
MEGF8 is a modifier of BMP signaling in trigeminal sensory neurons
GOA
curator
UniProt
UniProt protein ID
P60882
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
IMP
positive regulation of axon extension involved in axon guidance
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
MEGF8 is a modifier of BMP signaling in trigeminal sensory neurons
GOA
curator
UniProt
UniProt protein ID
P60882
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
IMP
coronary vasculature development
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
Global genetic analysis in mice unveils central role for cilia in congenital heart disease
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
IMP
BMP signaling pathway
determination method
IGI
1 reference
retrieved
9 May 2019
stated in
MEGF8 is a modifier of BMP signaling in trigeminal sensory neurons
GOA
curator
UniProt
UniProt protein ID
P60882
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
IGI
craniofacial suture morphogenesis
determination method
IEA
ISO
2 references
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
ISO
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
IEA
determination of left/right symmetry
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
Global genetic analysis in mice unveils central role for cilia in congenital heart disease
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
IMP
embryonic limb morphogenesis
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
MEGF8 is a modifier of BMP signaling in trigeminal sensory neurons
GOA
curator
UniProt
UniProt protein ID
P60882
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
IMP
embryonic heart tube morphogenesis
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
MEGF8 is a modifier of BMP signaling in trigeminal sensory neurons
GOA
curator
UniProt
UniProt protein ID
P60882
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
IMP
regulation of gene expression
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
MEGF8 is a modifier of BMP signaling in trigeminal sensory neurons
GOA
curator
UniProt
UniProt protein ID
P60882
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
IMP
left/right pattern formation
determination method
IEA
IMP
ISO
3 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
ISO
retrieved
14 February 2019
stated in
MEGF8 is a modifier of BMP signaling in trigeminal sensory neurons
GOA
curator
UniProt
UniProt protein ID
P60882
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
IMP
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
IEA
cell migration involved in gastrulation
determination method
IEA
ISO
2 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
IEA
fasciculation of sensory neuron axon
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
MEGF8 is a modifier of BMP signaling in trigeminal sensory neurons
GOA
curator
UniProt
UniProt protein ID
P60882
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
IMP
determination of digestive tract left/right asymmetry
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
Mouse model of heterotaxy with single ventricle spectrum of cardiac anomalies
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
IMP
negative regulation of smoothened signaling pathway
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
CRISPR Screens Uncover Genes that Regulate Target Cell Sensitivity to the Morphogen Sonic Hedgehog
GOA
curator
UniProt
UniProt protein ID
P60882
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
IMP
animal organ morphogenesis
determination method
IBA
1 reference
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
IBA
tissue development
determination method
IBA
1 reference
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
IBA
cell migration involved in gastrulation
determination method
IBA
IEA
ISO
3 references
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
ISO
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
IEA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
IBA
embryonic skeletal system morphogenesis
determination method
IBA
IMP
2 references
retrieved
9 May 2019
stated in
MEGF8 is a modifier of BMP signaling in trigeminal sensory neurons
GOA
curator
UniProt
UniProt protein ID
P60882
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
IMP
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
IBA
left/right pattern formation
determination method
IBA
IEA
IMP
ISO
4 references
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
ISO
retrieved
9 May 2019
stated in
MEGF8 is a modifier of BMP signaling in trigeminal sensory neurons
GOA
curator
UniProt
UniProt protein ID
P60882
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
IMP
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
IEA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
IBA
determination of heart left/right asymmetry
determination method
IBA
IEA
IMP
ISO
4 references
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
ISO
retrieved
9 May 2019
stated in
Mouse model of heterotaxy with single ventricle spectrum of cardiac anomalies
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
IMP
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
IEA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60882
determination method
IBA
has part(s)
CUB domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P60882
EGF-like calcium-binding, conserved site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P60882
Plexin repeat
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P60882
EGF-like calcium-binding domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P60882
EGF domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P60882
EGF-like, conserved site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P60882
EGF-type aspartate/asparagine hydroxylation site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P60882
PSI domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P60882
EGF-like domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P60882
Laminin EGF domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P60882
Identifiers
RefSeq protein ID
NP_001153872
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
269878
UniProt protein ID
P60882
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P60882
Ensembl protein ID
ENSMUSP00000122192
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000122192
Sitelinks
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Wikinews
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Wikiquote
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Wikisource
(0 entries)
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Wikiversity
(0 entries)
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Wikivoyage
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Multilingual sites
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