(Q21495981)

Homeobox domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Homeobox protein PKNOX/Meis, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Homeobox KN domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

9 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60954

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60954

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60954

14 February 2019

AbdB-like Hox proteins stabilize DNA binding by the Meis1 homeodomain proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60954

14 February 2019

The PDX1 homeodomain transcription factor negatively regulates the pancreatic ductal cell-specific keratin 19 promoter

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60954

14 February 2019

Hox/Pbx and Brn binding sites mediate Pax3 expression in vitro and in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60954

14 February 2019

Meis homeoproteins directly regulate Pax6 during vertebrate lens morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60954

14 February 2019

Meis proteins are major in vivo DNA binding partners for wild-type but not chimeric Pbx proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60954

14 February 2019

Meis1 and pKnox1 bind DNA cooperatively with Pbx1 utilizing an interaction surface disrupted in oncoprotein E2a-Pbx1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60954

DNA-binding transcription activator activity, RNA polymerase II-specific

2 references

24 April 2018

PBX1 and MEIS1 up-regulate SOX3 gene expression by direct interaction with a consensus binding site within the basal promoter region

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60954&geneProductId=UniProtKB:Q60954

14 February 2019

PBX1 and MEIS1 up-regulate SOX3 gene expression by direct interaction with a consensus binding site within the basal promoter region

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60954

1 reference

14 February 2019

Characterization of the murine Ephrin-B2 promoter

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60954

RNA polymerase II cis-regulatory region sequence-specific DNA binding

1 reference

14 February 2019

PBX1 and MEIS1 up-regulate SOX3 gene expression by direct interaction with a consensus binding site within the basal promoter region

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60954

transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding

1 reference

24 April 2018

Trimeric association of Hox and TALE homeodomain proteins mediates Hoxb2 hindbrain enhancer activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60954&geneProductId=UniProtKB:Q60954

DNA-binding transcription factor activity, RNA polymerase II-specific

1 reference

14 February 2019

Trimeric association of Hox and TALE homeodomain proteins mediates Hoxb2 hindbrain enhancer activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60954

transcription regulator complex

cell component

4 references

14 February 2019

Trimeric association of Hox and TALE homeodomain proteins mediates Hoxb2 hindbrain enhancer activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60954

14 February 2019

AbdB-like Hox proteins stabilize DNA binding by the Meis1 homeodomain proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60954

14 February 2019

Meis1 and pKnox1 bind DNA cooperatively with Pbx1 utilizing an interaction surface disrupted in oncoprotein E2a-Pbx1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60954

14 February 2019

Meis homeoproteins directly regulate Pax6 during vertebrate lens morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60954

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60954

7 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60954

14 February 2019

Three-amino-acid-loop-extension homeodomain factor Meis3 regulates cell survival via PDK1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60954

14 February 2019

Regulation of EphA8 gene expression by TALE homeobox transcription factors during development of the mesencephalon

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60954

14 February 2019

Range of HOX/TALE superclass associations and protein domain requirements for HOXA13:MEIS interaction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60954

14 February 2019

Pax6 is regulated by Meis and Pbx homeoproteins during pancreatic development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60954

14 February 2019

Expression of Meis and Pbx genes and their protein products in the developing telencephalon: implications for regional differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60954

14 February 2019

Meis proteins are major in vivo DNA binding partners for wild-type but not chimeric Pbx proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60954

megakaryocyte development

biological process

1 reference

14 February 2019

Platelets play an essential role in separating the blood and lymphatic vasculatures during embryonic angiogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60954

blood vessel morphogenesis

1 reference

14 February 2019

The homeodomain protein Meis1 is essential for definitive hematopoiesis and vascular patterning in the mouse embryo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60954

negative regulation of neuron differentiation

1 reference

14 February 2019

Altered neuronal lineages in the facial ganglia of Hoxa2 mutant mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60954

1 reference

14 February 2019

Restless legs syndrome-associated intronic common variant in Meis1 alters enhancer function in the developing telencephalon

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60954

regulation of transcription by RNA polymerase II

1 reference

14 February 2019

Trimeric association of Hox and TALE homeodomain proteins mediates Hoxb2 hindbrain enhancer activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60954

transcription, DNA-templated

IC

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60954&geneProductId=UniProtKB:Q60954

multicellular organism development

IEA

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60954

lens morphogenesis in camera-type eye

IEA

1 reference

14 February 2019

Hematopoietic, angiogenic and eye defects in Meis1 mutant animals

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60954

1 reference

14 February 2019

Hematopoietic, angiogenic and eye defects in Meis1 mutant animals

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60954

The homeodomain protein Meis1 is essential for definitive hematopoiesis and vascular patterning in the mouse embryo

definitive hemopoiesis

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60954

negative regulation of myeloid cell differentiation

1 reference

14 February 2019

Inhibition of myeloid differentiation by Hoxa9, Hoxb8, and Meis homeobox genes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60954

positive regulation of transcription by RNA polymerase II

1 reference

14 February 2019

PBX1 and MEIS1 up-regulate SOX3 gene expression by direct interaction with a consensus binding site within the basal promoter region

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60954

transcription by RNA polymerase II

1 reference

24 April 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60954&geneProductId=UniProtKB:Q60954

1 reference

14 February 2019

Hematopoietic, angiogenic and eye defects in Meis1 mutant animals

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60954

1 reference

Homeobox KN domain

1 reference

stated in

Homeobox protein PKNOX/Meis, N-terminal

1 reference

stated in