(Q21496809)

English

Regulatory factor X, 3 (influences HLA class II expression)

mammalian protein found in Mus musculus

Rfx3
transcription factor RFX3
regulatory factor X 3

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Statements

1 reference

25 May 2022

1 reference

19 January 2017

1 reference

25 May 2022

1 reference

25 May 2022

sequence-specific DNA binding

1 reference

9 May 2019

Evolutionarily dynamic alternative splicing of GPR56 regulates regional cerebral cortical patterning

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48381

determination method

IDA

DNA-binding transcription factor activity

1 reference

27 March 2018

The transcription factor Rfx3 regulates beta-cell differentiation, function, and glucokinase expression

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48381&geneProductId=UniProtKB:P48381

determination method

IDA

RNA polymerase II cis-regulatory region sequence-specific DNA binding

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48381

1 reference

9 May 2019

Rfx6 directs islet formation and insulin production in mice and humans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48381

determination method

IPI

DNA-binding transcription factor activity

determination method

IBA

IDA

DNA-binding transcription factor activity

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48381

9 May 2019

The transcription factor Rfx3 regulates beta-cell differentiation, function, and glucokinase expression

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48381

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48381

determination method

IBA

cell component

transcription regulator complex

1 reference

9 May 2019

The transcription factor Rfx3 regulates beta-cell differentiation, function, and glucokinase expression

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48381

1 reference

9 May 2019

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48381

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48381

determination method

IEA

regulation of transcription, DNA-templated

3 references

9 May 2019

RFX3 governs growth and beating efficiency of motile cilia in mouse and controls the expression of genes involved in human ciliopathies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48381

9 May 2019

The transcription factor RFX3 directs nodal cilium development and left-right asymmetry specification

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48381

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48381

determination method

IEA

positive regulation of type B pancreatic cell development

1 reference

9 May 2019

The transcription factor Rfx3 regulates beta-cell differentiation, function, and glucokinase expression

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48381

determination method

IMP

epithelial cilium movement involved in determination of left/right asymmetry

1 reference

9 May 2019

The transcription factor RFX3 directs nodal cilium development and left-right asymmetry specification

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48381

1 reference

9 May 2019

The transcription factor Rfx3 regulates beta-cell differentiation, function, and glucokinase expression

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48381

determination method

IMP

multicellular organism development

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48381

determination method

IEA

positive regulation of transcription, DNA-templated

3 references

determination of left/right symmetry

1 reference

9 May 2019

The transcription factor RFX3 directs nodal cilium development and left-right asymmetry specification

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48381

determination method

IMP

type B pancreatic cell maturation

1 reference

9 May 2019

The transcription factor Rfx3 regulates beta-cell differentiation, function, and glucokinase expression

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48381

determination method

IMP

negative regulation of transcription, DNA-templated

cilium-dependent cell motility

1 reference

9 May 2019

RFX3 governs growth and beating efficiency of motile cilia in mouse and controls the expression of genes involved in human ciliopathies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48381

determination method

IMP

endocrine pancreas development

1 reference

9 May 2019

Novel function of the ciliogenic transcription factor RFX3 in development of the endocrine pancreas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48381

determination method

IMP

positive regulation of transcription by RNA polymerase II

1 reference

9 May 2019

The transcription factor Rfx3 regulates beta-cell differentiation, function, and glucokinase expression

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48381

1 reference

9 May 2019

The transcription factor Rfx3 regulates beta-cell differentiation, function, and glucokinase expression

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48381

determination method

IMP

transcription, DNA-templated

1 reference

9 May 2019

RFX3 governs growth and beating efficiency of motile cilia in mouse and controls the expression of genes involved in human ciliopathies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48381

determination method

IMP

regulation of transcription by RNA polymerase II

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48381

determination method

IBA

Identifiers

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

(Q21496809)

Regulatory factor X, 3 (influences HLA class II expression)

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