(Q21497411)

http://www.ebi.ac.uk/interpro/protein/Q8K0C4

cytochrome P450, E-class, group IV

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8K0C4

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

cytochrome P450, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K0C4

monooxygenase activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

2 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K0C4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K0C4

oxidoreductase activity

1 reference

14 February 2019

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K0C4

sterol 14-demethylase activity

5 references

24 April 2018

Characterization of the mouse lanosterol 14alpha-demethylase (CYP51), a new member of the evolutionarily most conserved cytochrome P450 family

GOA

curator

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K0C4&geneProductId=UniProtKB:Q8K0C4

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K0C4&geneProductId=UniProtKB:Q8K0C4

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K0C4&geneProductId=UniProtKB:Q8K0C4

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K0C4&geneProductId=UniProtKB:Q8K0C4

24 April 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K0C4&geneProductId=UniProtKB:Q8K0C4

3 references

sterol 14-demethylase activity

5 references

14 February 2019

Characterization of the mouse lanosterol 14alpha-demethylase (CYP51), a new member of the evolutionarily most conserved cytochrome P450 family

GOA

curator

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K0C4

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K0C4

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K0C4

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K0C4

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K0C4

integral component of membrane

IBA

cell component

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K0C4

endoplasmic reticulum membrane

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K0C4

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K0C4

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K0C4

endoplasmic reticulum

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K0C4

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K0C4

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K0C4

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K0C4

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K0C4

intracellular membrane-bounded organelle

3 references

steroid metabolic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K0C4

cholesterol metabolic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K0C4

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K0C4

sterol biosynthetic process

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8K0C4&geneProductId=UniProtKB:Q8K0C4

steroid biosynthetic process

3 references

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K0C4

cholesterol biosynthetic process via 24,25-dihydrolanosterol

3 references

sterol metabolic process

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K0C4

negative regulation of protein catabolic process

IBA

1 reference

14 February 2019

Statins promote the degradation of extracellular amyloid {beta}-peptide by microglia via stimulation of exosome-associated insulin-degrading enzyme (IDE) secretion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K0C4

negative regulation of protein secretion

IMP

1 reference

14 February 2019

Statins promote the degradation of extracellular amyloid {beta}-peptide by microglia via stimulation of exosome-associated insulin-degrading enzyme (IDE) secretion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K0C4

negative regulation of amyloid-beta clearance

IMP

1 reference

14 February 2019

Statins promote the degradation of extracellular amyloid {beta}-peptide by microglia via stimulation of exosome-associated insulin-degrading enzyme (IDE) secretion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8K0C4

cytochrome P450, conserved site

IMP

has part(s)

1 reference

stated in

InterPro Release 71.0