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6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
mammalian protein found in Mus musculus
6PF-2-K/Fru-2,6-P2ase 2
PFK/FBPase 2
PFK-2/FBPase-2 gene B
Pfkfb2
6PF-2-K/Fru-2,6-P2ase heart-type isozyme
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2
In more languages
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No label defined
No description defined
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P70265
subclass of
protein
1 reference
stated in
UniProt
retrieved
19 January 2017
UniProt protein ID
P70265
part of
Histidine phosphatase superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P70265
6-phosphofructo-2-kinase (subset)
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P70265
P-loop containing nucleoside triphosphate hydrolase
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P70265
Phosphoglycerate/bisphosphoglycerate mutase, active site, protein family
1 reference
based on heuristic
inferred from protein domain or family
phosphofructokinase 2
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
house mouse
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P70265
encoded by
Pfkfb2
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P70265
molecular function
protein kinase binding
determination method or standard
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70265
determination method or standard
ISO
transferase activity
determination method or standard
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P70265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70265
determination method or standard
IEA
nucleotide binding
determination method or standard
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P70265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70265
determination method or standard
IEA
kinase activity
determination method or standard
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P70265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70265
determination method or standard
IEA
catalytic activity
determination method or standard
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P70265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70265
determination method or standard
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70265
determination method or standard
IEA
hydrolase activity
determination method or standard
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P70265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70265
determination method or standard
IEA
ATP binding
determination method or standard
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P70265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70265
determination method or standard
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70265
determination method or standard
IEA
6-phosphofructo-2-kinase activity
determination method or standard
IEA
ISS
ISO
4 references
retrieved
24 April 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P70265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70265&geneProductId=UniProtKB:P70265
determination method or standard
ISS
retrieved
24 April 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70265&geneProductId=UniProtKB:P70265
determination method or standard
ISO
retrieved
24 April 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P70265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70265&geneProductId=UniProtKB:P70265
determination method or standard
IEA
retrieved
24 April 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70265&geneProductId=UniProtKB:P70265
determination method or standard
IEA
fructose-2,6-bisphosphate 2-phosphatase activity
determination method or standard
IDA
IEA
ISO
3 references
retrieved
24 April 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70265&geneProductId=UniProtKB:P70265
determination method or standard
ISO
retrieved
24 April 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P70265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70265&geneProductId=UniProtKB:P70265
determination method or standard
IEA
retrieved
24 April 2018
stated in
A role for PFK-2/FBPase-2, as distinct from fructose 2,6-bisphosphate, in regulation of insulin secretion in pancreatic beta-cells
GOA
curator
Community Assessment of Community Annotation with Ontologies
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70265&geneProductId=UniProtKB:P70265
determination method or standard
IDA
kinase binding
determination method or standard
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70265
determination method or standard
ISO
6-phosphofructo-2-kinase activity
determination method or standard
IBA
IEA
ISO
ISS
5 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P70265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70265
determination method or standard
ISS
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70265
determination method or standard
ISO
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P70265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70265
determination method or standard
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70265
determination method or standard
IEA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70265
determination method or standard
IBA
fructose-2,6-bisphosphate 2-phosphatase activity
determination method or standard
IBA
IDA
IEA
ISO
4 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70265
determination method or standard
ISO
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P70265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70265
determination method or standard
IEA
retrieved
14 February 2019
stated in
A role for PFK-2/FBPase-2, as distinct from fructose 2,6-bisphosphate, in regulation of insulin secretion in pancreatic beta-cells
GOA
curator
Community Assessment of Community Annotation with Ontologies
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70265
determination method or standard
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70265
determination method or standard
IBA
cell component
nucleus
determination method or standard
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70265
determination method or standard
ISO
nucleoplasm
determination method or standard
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70265
determination method or standard
ISO
cytoplasm
determination method or standard
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70265
determination method or standard
ISO
cytosol
determination method or standard
IBA
1 reference
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70265
determination method or standard
IBA
biological process
glycolytic process
determination method or standard
ISS
ISO
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P70265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70265
determination method or standard
ISS
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70265
determination method or standard
ISO
phosphorylation
determination method or standard
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P70265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70265
determination method or standard
IEA
fructose metabolic process
determination method or standard
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70265
determination method or standard
IEA
fructose 2,6-bisphosphate metabolic process
determination method or standard
IEA
1 reference
retrieved
24 April 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P70265&geneProductId=UniProtKB:P70265
determination method or standard
IEA
metabolism
determination method or standard
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P70265
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70265
determination method or standard
IEA
carbohydrate phosphorylation
determination method or standard
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70265
determination method or standard
IEA
dephosphorylation
determination method or standard
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70265
determination method or standard
IEA
glucose catabolic process
determination method or standard
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70265
determination method or standard
ISO
lactate metabolic process
determination method or standard
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70265
determination method or standard
ISO
pyruvate metabolic process
determination method or standard
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70265
determination method or standard
ISO
response to glucose
determination method or standard
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70265
determination method or standard
ISO
positive regulation of insulin secretion
determination method or standard
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70265
determination method or standard
ISO
positive regulation of glucokinase activity
determination method or standard
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70265
determination method or standard
ISO
fructose 2,6-bisphosphate metabolic process
determination method or standard
IBA
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70265
determination method or standard
IEA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70265
determination method or standard
IBA
has part(s)
6-phosphofructo-2-kinase domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P70265
Phosphoglycerate/bisphosphoglycerate mutase, active site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P70265
Identifiers
RefSeq protein ID
NP_001155887
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
18640
NP_001155888
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
18640
NP_032851
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
18640
NP_001355772
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
18640
UniProt protein ID
P70265
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P70265
Ensembl protein ID
ENSMUSP00000066426
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000066426
ENSMUSP00000127587
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000127587
ENSMUSP00000129747
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000129747
ENSMUSP00000133073
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000133073
ENSMUSP00000140068
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000140068
ENSMUSP00000140355
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000140355
ENSMUSP00000140551
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000140551
ENSMUSP00000140612
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000140612
ENSMUSP00000140698
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000140698
ENSMUSP00000140799
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000140799
ENSMUSP00000140984
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000140984
ENSMUSP00000140995
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000140995
Sitelinks
Wikipedia
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Wikinews
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Wikiquote
(0 entries)
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Wikisource
(0 entries)
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Wikiversity
(0 entries)
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Wikivoyage
(0 entries)
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Wiktionary
(0 entries)
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Multilingual sites
(0 entries)
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