(Q21498176)

PDZ superfamily

1 reference

membrane protein

1 reference

inferred from GOA cell component → membrane

PDZ domain, protein family

1 reference

inferred from protein domain or family

Leucine-rich repeat, typical subtype, protein family

1 reference

inferred from protein domain or family

Leucine-rich repeat, protein family

1 reference

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

6 references

9 May 2019

Human scribble, a novel tumor suppressor identified as a target of high-risk HPV E6 for ubiquitin-mediated degradation, interacts with adenomatous polyposis coli

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

9 May 2019

Scrib regulates PAK activity during the cell migration process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

9 May 2019

Asymmetric localization of Vangl2 and Fz3 indicate novel mechanisms for planar cell polarity in mammals

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

9 May 2019

Scribble interacts with beta-catenin to localize synaptic vesicles to synapses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

9 May 2019

Regulation of a late phase of T cell polarity and effector functions by Crtam

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

9 May 2019

Scribble-mediated membrane targeting of PHLPP1 is required for its negative regulation of Akt

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

guanylate kinase activity

IPI

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q80U72&geneProductId=UniProtKB:Q80U72

ionotropic glutamate receptor binding

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q80U72&geneProductId=UniProtKB:Q80U72

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

myelin sheath abaxonal region

1 reference

9 May 2019

Pals1 is a major regulator of the epithelial-like polarization and the extension of the myelin sheath in peripheral nerves

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

Nuclear localization of Prickle2 is required to establish cell polarity during early mouse embryogenesis

cell-cell contact zone

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

ionotropic glutamate receptor complex

IDA

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

postsynaptic membrane

4 references

9 May 2019

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

apical plasma membrane

1 reference

9 May 2019

Atypical Cadherin Fat1 Is Required for Lens Epithelial Cell Polarity and Proliferation but Not for Fiber Differentiation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

basolateral plasma membrane

3 references

9 May 2019

Asymmetric localization of Vangl2 and Fz3 indicate novel mechanisms for planar cell polarity in mammals

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

9 May 2019

Nuclear localization of Prickle2 is required to establish cell polarity during early mouse embryogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

establishment of apical/basal cell polarity

synaptic vesicle targeting

1 reference

9 May 2019

Scribble interacts with beta-catenin to localize synaptic vesicles to synapses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

activation of GTPase activity

apoptotic process involved in morphogenesis

1 reference

9 May 2019

Epidermal wound repair is regulated by the planar cell polarity signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

auditory receptor cell morphogenesis

IGI

1 reference

9 May 2019

Planar cell polarity defects and defective Vangl2 trafficking in mutants for the COPII gene Sec24b

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

mammary gland duct morphogenesis

IGI

1 reference

9 May 2019

Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

multicellular organism development

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

auditory receptor cell stereocilium organization

1 reference

9 May 2019

Planar cell polarity defects and defective Vangl2 trafficking in mutants for the COPII gene Sec24b

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

synaptic vesicle endocytosis

1 reference

21 June 2018

Scribble interacts with beta-catenin to localize synaptic vesicles to synapses

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q80U72&geneProductId=UniProtKB:Q80U72

positive regulation of apoptotic process

morphogenesis of embryonic epithelium

1 reference

9 May 2019

Disruption of scribble (Scrb1) causes severe neural tube defects in the circletail mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

cell population proliferation

cochlear nucleus development

1 reference

9 May 2019

Planar cell polarity defects and defective Vangl2 trafficking in mutants for the COPII gene Sec24b

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

negative regulation of mitotic cell cycle

IGI

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

GMP metabolic process

1 reference

21 June 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q80U72&geneProductId=UniProtKB:Q80U72

GDP metabolic process

1 reference

21 June 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q80U72&geneProductId=UniProtKB:Q80U72

receptor localization to synapse

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

1 reference

9 May 2019

Asymmetric localization of Vangl2 and Fz3 indicate novel mechanisms for planar cell polarity in mammals

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

epithelial cell morphogenesis

1 reference

9 May 2019

Atypical Cadherin Fat1 Is Required for Lens Epithelial Cell Polarity and Proliferation but Not for Fiber Differentiation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

establishment or maintenance of epithelial cell apical/basal polarity

1 reference

21 June 2018

Atypical Cadherin Fat1 Is Required for Lens Epithelial Cell Polarity and Proliferation but Not for Fiber Differentiation.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q80U72&geneProductId=UniProtKB:Q80U72

camera-type eye morphogenesis

1 reference

9 May 2019

Atypical Cadherin Fat1 Is Required for Lens Epithelial Cell Polarity and Proliferation but Not for Fiber Differentiation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

establishment or maintenance of epithelial cell apical/basal polarity

synaptic vesicle endocytosis

3 references

9 May 2019

Scribble interacts with beta-catenin to localize synaptic vesicles to synapses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

9 May 2019

Scribble interacts with beta-catenin to localize synaptic vesicles to synapses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

9 May 2019

Scribble interacts with beta-catenin to localize synaptic vesicles to synapses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

neurotransmitter receptor transport, endosome to postsynaptic membrane

neurotransmitter receptor transport postsynaptic membrane to endosome

establishment or maintenance of epithelial cell apical/basal polarity

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

5 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

9 May 2019

Epidermal wound repair is regulated by the planar cell polarity signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

9 May 2019

Focusing forward genetics: a tripartite ENU screen for neurodevelopmental mutations in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

9 May 2019

Focusing forward genetics: a tripartite ENU screen for neurodevelopmental mutations in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

inner ear receptor cell stereocilium organization

1 reference

9 May 2019

Focusing forward genetics: a tripartite ENU screen for neurodevelopmental mutations in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U72

leucine-rich repeat, typical subtype

has part(s)

1 reference

Leucine-rich repeat

1 reference

PDZ domain

1 reference