(Q35793534)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26114487%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

title

Atypical Cadherin Fat1 Is Required for Lens Epithelial Cell Polarity and Proliferation but Not for Fiber Differentiation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26114487%20AND%20SRC:MED&resulttype=core&format=json

Scribbled planar cell polarity

18 February 2020

main subject

1 reference

GOA release 2020-03-11

author

Helen McNeill

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26114487%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

author name string

Yuki Sugiyama

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26114487%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

Elizabeth J Shelley

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26114487%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

Caroline Badouel

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26114487%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

John W McAvoy

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26114487%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

language of work or name

English

0 references

publication date

1 June 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26114487%20AND%20SRC:MED&resulttype=core&format=json

Investigative Ophthalmology Visual Science

18 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26114487%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

volume

56

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26114487%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26114487%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

page(s)

4099-4107

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26114487%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

18 February 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4484397/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Dual function of Yap in the regulation of lens progenitor cells and cellular polarity.

1 reference

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Sfrp1 and Sfrp2 are not involved in Wnt/β-catenin signal silencing during lens induction but are required for maintenance of Wnt/β-catenin signaling in lens epithelial cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484397

Scrib is required for epithelial cell identity and prevents epithelial to mesenchymal transition in the mouse

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484397

Deregulation of the protocadherin gene FAT1 alters muscle shapes: implications for the pathogenesis of facioscapulohumeral dystrophy

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484397

Sleeping giants: emerging roles for the fat cadherins in health and disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484397

Notch2 regulates BMP signaling and epithelial morphogenesis in the ciliary body of the mouse eye

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484397

Fat and Dachsous cadherins

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484397

Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484397

Scribble acts in the Drosophila fat-hippo pathway to regulate warts activity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484397

Functional interactions between Fat family cadherins in tissue morphogenesis and planar polarity.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484397

Control of neuronal morphology by the atypical cadherin Fat3

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484397

Dual processing of FAT1 cadherin protein by human melanoma cells generates distinct protein products

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484397

Characterization of a Dchs1 mutant mouse reveals requirements for Dchs1-Fat4 signaling during mammalian development

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484397

The lens epithelium in ocular health and disease.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484397

The tumor suppressor merlin is required for cell cycle exit, terminal differentiation, and cell polarity in the developing murine lens

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484397

Lens gap junctions in growth, differentiation, and homeostasis.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484397

Pax6-dependent Shroom3 expression regulates apical constriction during lens placode invagination

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484397

Secreted frizzled-related protein disrupts PCP in eye lens fiber cells that have polarised primary cilia

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484397

A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q- syndrome

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484397

A cell polarity protein aPKClambda is required for eye lens formation and growth

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484397

Scribble participates in Hippo signaling and is required for normal zebrafish pronephros development

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484397

Differential requirement for beta-catenin in epithelial and fiber cells during lens development

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484397

Lens ion transport: from basic concepts to regulation of Na,K-ATPase activity.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484397

Mitochondrial function and redox control in the aging eye: role of MsrA and other repair systems in cataract and macular degenerations

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484397

The Notch signaling pathway controls the size of the ocular lens by directly suppressing p57Kip2 expression

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484397

Protocadherin FAT1 binds Ena/VASP proteins and is necessary for actin dynamics and cell polarization.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484397

Mammalian Fat1 cadherin regulates actin dynamics and cell-cell contact

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484397

Mice lacking the giant protocadherin mFAT1 exhibit renal slit junction abnormalities and a partially penetrant cyclopia and anophthalmia phenotype.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484397

The fat tumor suppressor gene in Drosophila encodes a novel member of the cadherin gene superfamily

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484397

The atypical cadherin fat directly regulates mitochondrial function and metabolic state

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484397

Conditional mutations of beta-catenin and APC reveal roles for canonical Wnt signaling in lens differentiation.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484397

Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484397

Localization of PDZ domain containing proteins Discs Large-1 and Scribble in the mouse eye.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4484397

A role for Wnt/beta-catenin signaling in lens epithelial differentiation

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26114487

12 December 2020

inferred from PubMed ID database lookup

Cell division, cell elongation and distribution of alpha-, beta- and gamma-crystallins in the rat lens

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26114487

12 December 2020

inferred from PubMed ID database lookup

Appearance of alpha-smooth muscle actin in human eye lens cells of anterior capsular cataract and in cultured bovine lens-forming cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26114487

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1167/IOVS.15-17008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26114487%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26114487%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

PubMed publication ID

26114487

1 reference