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English
Egl-9 family hypoxia-inducible factor 3
mammalian protein found in Mus musculus
HIF-prolyl hydroxylase 3
HIF-PH3
PHD3
SM-20
hypoxia-inducible factor prolyl hydroxylase 3
prolyl hydroxylase EGLN3
Egln3
prolyl hydroxylase domain-containing protein 3
egl nine homolog 3
HPH-3
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q91UZ4
subclass of
protein
1 reference
stated in
UniProt
retrieved
19 January 2017
UniProt protein ID
Q91UZ4
part of
Prolyl 4-hydroxylase, alpha subunit, protein family
1 reference
based on heuristic
inferred from protein domain or family
Oxoglutarate/iron-dependent dioxygenase family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
house mouse
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q91UZ4
encoded by
Egln3
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q91UZ4
molecular function
2-oxoglutarate-dependent dioxygenase activity
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91UZ4
determination method
ISO
iron ion binding
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91UZ4
determination method
IEA
L-ascorbic acid binding
determination method
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q91UZ4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91UZ4
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91UZ4
determination method
IEA
dioxygenase activity
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q91UZ4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91UZ4
determination method
IEA
metal ion binding
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q91UZ4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91UZ4
determination method
IEA
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91UZ4
determination method
IEA
oxidoreductase activity
determination method
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q91UZ4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91UZ4
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91UZ4
determination method
IEA
peptidyl-proline 4-dioxygenase activity
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91UZ4
determination method
ISO
peptidyl-proline dioxygenase activity
determination method
IDA
1 reference
retrieved
14 February 2019
stated in
Advanced glycated end-products affect HIF-transcriptional activity in renal cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91UZ4
determination method
IDA
cell component
cytoplasm
determination method
ISS
IEA
ISO
3 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q91UZ4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91UZ4
determination method
ISS
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91UZ4
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q91UZ4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91UZ4
determination method
IEA
nucleus
determination method
ISS
IEA
ISO
3 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q91UZ4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91UZ4
determination method
ISS
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91UZ4
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q91UZ4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91UZ4
determination method
IEA
cytosol
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91UZ4
determination method
ISO
biological process
regulation of neuron apoptotic process
determination method
IMP
1 reference
retrieved
14 February 2019
stated in
Abnormal sympathoadrenal development and systemic hypotension in PHD3-/- mice
GOA
curator
UniProt
UniProt protein ID
Q91UZ4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91UZ4
determination method
IMP
peptidyl-proline hydroxylation to 4-hydroxy-L-proline
determination method
ISO
1 reference
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91UZ4
determination method
ISO
cellular response to DNA damage stimulus
determination method
IEA
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q91UZ4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91UZ4
determination method
IEA
activation of cysteine-type endopeptidase activity involved in apoptotic process
determination method
ISS
1 reference
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q91UZ4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91UZ4
determination method
ISS
protein hydroxylation
determination method
ISS
ISO
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q91UZ4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91UZ4
determination method
ISS
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91UZ4
determination method
ISO
apoptotic process
determination method
ISS
IEA
2 references
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q91UZ4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91UZ4
determination method
ISS
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q91UZ4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91UZ4
determination method
IEA
cellular response to leukemia inhibitory factor
determination method
IEP
1 reference
retrieved
14 February 2019
stated in
miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic stem cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91UZ4
determination method
IEP
regulation of cell population proliferation
determination method
IMP
ISO
2 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91UZ4
determination method
ISO
retrieved
14 February 2019
stated in
Abnormal sympathoadrenal development and systemic hypotension in PHD3-/- mice
GOA
curator
UniProt
UniProt protein ID
Q91UZ4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91UZ4
determination method
IMP
has part(s)
Oxoglutarate/iron-dependent dioxygenase
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q91UZ4
Prolyl 4-hydroxylase, alpha subunit
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q91UZ4
Identifiers
RefSeq protein ID
NP_082409
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
112407
XP_036013061
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
112407
UniProt protein ID
Q91UZ4
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q91UZ4
Ensembl protein ID
ENSMUSP00000041874
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000041874
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Multilingual sites
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